H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2
- Product Name
- H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2
- CAS No.
- 208041-90-1
- Chemical Name
- H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2
- Synonyms
- HEMOKININ-1;HK-1, MOUSE;HEK-1, MOUSE;HK-1 (MOUSE, RAT);HEK-1 (MOUSE, RAT);HEMOKININ 1 (MOUSE);H2N-RSRTRQFYGLM-AMIDE;HEMOKININ 1 (MOUSE, RAT);HEMOKININ 1 MOUSE?, >98%;Hemokinin 1 mouse,RSRTRQFYGLM, >98%
- CBNumber
- CB3195426
- Molecular Formula
- C61H100N22O15S
- Formula Weight
- 1413.65
- MOL File
- 208041-90-1.mol
H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Property
- Density
- 1.48±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- H2O: soluble
- pka
- 9.82±0.15(Predicted)
- form
- powder
- color
- white
- Water Solubility
- Soluble to 2 mg/ml in water
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- CS-7597
- Product name
- Hemokinin1mouse
- Purity
- 98.41%
- Packaging
- 1mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- orb372368
- Product name
- Hemokinin 1
- Purity
- > 95%
- Packaging
- 1mg
- Price
- $353.6
- Updated
- 2021/12/16
- Product number
- orb372369
- Product name
- Hemokinin 1
- Purity
- > 95%
- Packaging
- 1mg
- Price
- $353.6
- Updated
- 2021/12/16
- Product number
- CS-7597
- Product name
- Hemokinin1mouse
- Purity
- 98.41%
- Packaging
- 5mg
- Price
- $540
- Updated
- 2021/12/16
- Product number
- orb372369
- Product name
- Hemokinin 1
- Purity
- > 95%
- Packaging
- 5mg
- Price
- $688.5
- Updated
- 2021/12/16
H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Chemical Properties,Usage,Production
Uses
Hemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively.
in vivo
Hemokinin 1 (mouse) (0.01-100 nmol/kg i.v., n=10) induces a dose-related hypotension that is maximal at the dose of 10 nmol/kg. For systolic blood pressure (SBP), the ED50 value is 0.2 nmol/kg (0.1-0.4 nmol/kg) for Hemokinin 1 (mouse). For diastolic blood pressure (DBP), the ED50 value is 0.1 nmol/kg (0.07-0.2 nmol/kg) for Hemokinin 1 (mouse). Hemokinin 1 (mouse) (0.1-100 nmol/kg, i.v.) induces a dose-related salivary secretion in atropine-pretreated rats[1].
IC 50
NK1
References
[1] Francesca Bellucci, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol. 2002 Jan; 135(1): 266-274
H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Preparation Products And Raw materials
Raw materials
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View Lastest Price from H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 manufacturers
- Product
- H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 208041-90-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-03-05