ChemicalBook > CAS DataBase List > 3,5-Dimethyl-4-nitro-1H-pyrazole

3,5-Dimethyl-4-nitro-1H-pyrazole

Product Name
3,5-Dimethyl-4-nitro-1H-pyrazole
CAS No.
14531-55-6
Chemical Name
3,5-Dimethyl-4-nitro-1H-pyrazole
Synonyms
AKOS 90439;AKOS B001468;ART-CHEM-BB B001468;TIMTEC-BB SBB009217;3,5-DiMethyl-4-nitro;3,5-Dimethyl-4-nitropyrazole>3,5-DIMETHYL-4-NITRO-1H-PYRAZOLE;4-NITRO-3,5-DIMETHYL-1H-PYRAZOLE;1H-Pyrazole, 3,5-dimethyl-4-nitro-;1H-Pyrazole,3,5-dimethyl-4-nitro-(9CI)
CBNumber
CB3198467
Molecular Formula
C5H7N3O2
Formula Weight
141.13
MOL File
14531-55-6.mol
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3,5-Dimethyl-4-nitro-1H-pyrazole Property

Melting point:
125.0 to 129.0 °C
Boiling point:
325°C(lit.)
Density 
1.339±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
10.75±0.50(Predicted)
color 
White to Almost white
λmax
274nm(CHCl3)(lit.)
InChI
InChI=1S/C5H7N3O2/c1-3-5(8(9)10)4(2)7-6-3/h1-2H3,(H,6,7)
InChIKey
OFQCJVVJRNPSET-UHFFFAOYSA-N
SMILES
N1C(C)=C([N+]([O-])=O)C(C)=N1
CAS DataBase Reference
14531-55-6(CAS DataBase Reference)
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Safety

RTECS 
UQ6585000
HazardClass 
IRRITANT
HS Code 
2933199090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
D4425
Product name
3,5-Dimethyl-4-nitropyrazole
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$40
Updated
2025/07/31
TCI Chemical
Product number
D4425
Product name
3,5-Dimethyl-4-nitropyrazole
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$194
Updated
2025/07/31
TRC
Product number
D480550
Product name
3,5-Dimethyl-4-nitro-1H-pyrazole
Packaging
250mg
Price
$45
Updated
2021/12/16
Chem-Impex
Product number
43650
Product name
3,5-Dimethyl-4-nitropyrazole,≥98%(GC)
Purity
≥98%(GC)
Packaging
5G
Price
$48.54
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD40735
Product name
3,5-Dimethyl-4-nitRopyRazole
Packaging
10g
Price
$107
Updated
2021/12/16
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3,5-Dimethyl-4-nitro-1H-pyrazole Chemical Properties,Usage,Production

Uses

As Pyrazoles compound, 3,5-Dimethyl-4-nitro-1H-pyrazole has the key structures in numerous compounds of therapeutic importance. Compounds containing this ring system are known to display diverse pharmacological activities, for example as antimalarial agents , anti-inflammatory agents, and against cardiovascular disease.[1]

Synthesis

2033-45-6

14531-55-6

General procedure for the synthesis of 3,5-dimethyl-4-nitropyrazole from 3,5-dimethyl-4-iodopyrazole: 1. 3,5-dimethyl-4-iodopyrazole (1 mmol) was dissolved in tetrahydrofuran (THF, 10 mL). 2. Add Fuajasite catalyst (250 mg) to the above solution. 3. Concentrated nitric acid (density 1.52 g/cm3, 10 mL) was added slowly. 4. Stir the reaction mixture at room temperature until the reaction is complete. 5. 5. Upon completion of the reaction, the catalyst was filtered to recover the catalyst. 6. 6. The filtrate was extracted several times with dichloromethane. 7. 7. The organic phases were combined and concentrated in vacuum to remove the solvent to give 3,5-dimethyl-4-nitropyrazole.

References

[1] Edward R T Tiekink,  James L Wardell,  Solange M S V Wardell. “3,5-Dimethyl-1-(4-nitro-phen-yl)-1H-pyrazole.” Acta crystallographica. Section E, Structure reports online 68 Pt 4 (2012): o1018.

3,5-Dimethyl-4-nitro-1H-pyrazole Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-Dimethyl-4-nitro-1H-pyrazole Suppliers

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View Lastest Price from 3,5-Dimethyl-4-nitro-1H-pyrazole manufacturers

Honest Joy Holdings Limited
Product
3,5-Dimethyl-4-nitro-1H-pyrazole 14531-55-6
Price
US $0.00/KG
Min. Order
1KG
Purity
97.1%
Supply Ability
100 tons
Release date
2022-01-26
Career Henan Chemical Co
Product
3,5-Dimethyl-4-nitro-1H-pyrazole 14531-55-6
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
500kg/month
Release date
2019-08-01

14531-55-6, 3,5-Dimethyl-4-nitro-1H-pyrazoleRelated Search:

Dacthal 3,5-Dimethylpyrazole Dimethyl carbonate N,N-Dimethylformamide Dimethyl sulfoxide Pyraclostrobin Dimethyl ether Pyrazole Dimethyl fumarate ETHANE Dimethyl sulfate Dimethyl disulfide Zolpidem tartrate Zolpidem 2,5-dimethyl-4-nitro-2H-pyrazole-3- 5-CHLORO-1,3-DIMETHYL-4-NITRO-1H-PYRAZOLE 4-Nitropyrazole 1-ACETYL-3(5)-(HEPTAFLUORO-1-PROPYL)-5(3)-METHYL-4-(NITRO)PYRAZOLE

  • ART-CHEM-BB B001468
  • AKOS 90439
  • AKOS B001468
  • 4-NITRO-3,5-DIMETHYL-1H-PYRAZOLE
  • 3,5-DIMETHYL-4-NITRO-1H-PYRAZOLE
  • TIMTEC-BB SBB009217
  • 5-23-05-00160 (Beilstein Handbook Reference)
  • 1H-Pyrazole,3,5-dimethyl-4-nitro-(9CI)
  • 3,5-dimethyl-4-nitro-1H-pyrazole(SALTDATA: FREE)
  • 3,5-DiMethyl-4-nitro
  • 3,5-Dimethyl-4-nitropyrazole&gt
  • 1H-Pyrazole, 3,5-dimethyl-4-nitro-
  • 14531-55-6
  • NITRO