ChemicalBook > CAS DataBase List > 2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER

2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER

Product Name
2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER
CAS No.
193537-14-3
Chemical Name
2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER
Synonyms
6-(TERT-BUTYL) 3-ETHYL 2-AMINO-4,7-DIHYDROTHIENO[2,3-C]PYRIDINE-3,6(5H)-DICARBOXYLATE;Ethyl 6-Boc-2-amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3-carboxylate;106278;ST5408868;ZINC04287569;BUTTPARK 75\08-01;Ethyl 2-aMino-6-Boc-4,7-d...;2-Amino-4,7-Dihydro-5H-Thieno[2,3-C]Pyridine-3,6-Dicarboxyli...;Ethyl 2-amino-6-Boc-4,7-dihydro-5H-thieno[2,3-c]pyridine-3-carboxylate;Ethyl 2-aMino-6-Boc-4,7-dihydro-5H-thieno[3,2-c]pyridine-3-carboxylate
CBNumber
CB3198472
Molecular Formula
C15H22N2O4S
Formula Weight
326.41
MOL File
193537-14-3.mol
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2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER Property

Melting point:
153 °C
Boiling point:
492.5±45.0 °C(Predicted)
Density 
1.252±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
0.40±0.20(Predicted)
Appearance
Light yellow to yellow Solid
CAS DataBase Reference
193537-14-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/39
Hazard Note 
Irritant
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T141453
Product name
6-tert-Butyl 3-ethyl 2-amino-4,7-dihydrothieno[2,3-c]pyridine-3,6(5H)-dicarboxylate
Purity
AldrichCPR
Packaging
5MG
Price
$30.7
Updated
2025/07/31
TRC
Product number
E900148
Product name
Ethyl6-Boc-2-amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3-carboxylate
Packaging
100mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
8H58-1-35
Product name
Ethyl 2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate, N-Boc protected
Purity
95%
Packaging
250mg
Price
$38
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB135848
Product name
6-tert-Butyl 3-ethyl 2-amino-4,7-dihydrothieno[2,3-c]pyridine-3,6(5H)-dicarboxylate
Packaging
500mg
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
OR14010
Product name
Ethyl2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate,N-BOCprotected
Packaging
1g
Price
$87
Updated
2021/12/16
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2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER Chemical Properties,Usage,Production

Synthesis

79099-07-3

105-56-6

193537-14-3

General Steps: Step a. Synthesis of 2-amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3,6-dicarboxylic acid 6-tert-butyl 3-ethyl ester In anhydrous ethanol (50 mL), N-tert-butoxycarbonyl-4-piperidone (12.9 g), ethyl cyanoacetate (7.345 g), and sulfur powder (2.080 g) were mixed, followed by the addition of triethylamine (9 mL). The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the precipitate was collected by filtration and washed with ethanol to afford 2-amino-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylic acid-6-tert-butyl ester (18.7 g, 88% yield). Product characterization data: 1H NMR (300 MHz, CDCl3): δ 6.02 (s, 2H), 4.31 (s, 2H), 4.23 (q, 2H, J = 7.2 Hz), 3.58 (t, 2H, J = 6.0 Hz), 2.72-2.80 (br s, 2H), 1.44 (s, 9H), 1.30 (t, 3H, J = 7.2 Hz). LC-MS (ESI) m/z: 327.0 (M + H)+.

References

[1] Synlett, 2010, # 9, p. 1351 - 1354
[2] Patent: US2010/120805, 2010, A1. Location in patent: Page/Page column 44
[3] Journal of Medicinal Chemistry, 2010, vol. 53, # 20, p. 7316 - 7326
[4] Patent: WO2009/33581, 2009, A1. Location in patent: Page/Page column 62
[5] Journal of Medicinal Chemistry, 2012, vol. 55, # 7, p. 3101 - 3112

2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER Suppliers

Belgium 1 China 89 Germany 2 India 3 United Kingdom 9 United States 19 Global 123
Maybridge Chemical Co., Ltd.
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Country
Belgium
ProdList
6293
Advantage
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View Lastest Price from 2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
6-tert-butyl 3-ethyl 2-amino-4H,5H,6H,7H-thieno[2,3-c]pyridine-3,6-dicarboxylate 193537-14-3
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-04-30
Career Henan Chemical Co
Product
2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER 193537-14-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2019-07-11

193537-14-3, 2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTERRelated Search:

Ethyl oxazole-4-carboxylate ethyl 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)acetate ETHYL 2 3-BUTADIENOATE 95 Ethyl 2-(hydroxymethyl)acrylate ethyl 2-((ethoxycarbonyl)amino)-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate ETHYL 2,3-EPOXYPROPANOATE ethyl 6-(trifluoromethyl)tetrahydro-2H-pyran-3-carboxylate Ethyl 6-oxohexanoate ETHYL 2-(BROMOMETHYL)ACRYLATE ETHYL 2,3,4-TRI-O-BENZYL-1-THIO-BETA-L-FUCOPYRANOSIDE ETHYL 2-OXAZOLECARBOXYLATE 2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER TERT-BUTYL FORMATE 6-BOC-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID (2-THIOPHEN-3-YL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER BUTTPARK 93\08-100 BUTTPARK 77\08-23 BUTTPARK 77\08-24

  • Ethyl2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate,N-BOCprotected95%
  • Ethyl 2-amino-6-Boc-4,7-dihydro-5H-thieno[2,3-c]pyridine-3-carboxylate
  • 6-O-tert-butyl 3-O-ethyl 2-amino-5,7-dihydro-4H-thieno[2,3-c]pyridine-3,6-dicarboxylate
  • 2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER
  • 6-TERT-BUTYL 3-ETHYL-2-AMINO-4,5-DIHYDRO-THIENO[2,3-C]PYRIDINE-3,6(7H)-DICARBOXYLATE
  • 6-(TERT-BUTYL) 3-ETHYL 2-AMINO-4,7-DIHYDROTHIENO[2,3-C]PYRIDINE-3,6(5H)-DICARBOXYLATE
  • BUTTPARK 75\08-01
  • Ethyl 2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate, N-BOC protected
  • Ethyl 2-amino-6-tertbutoxycarbonyl-4,5,6,7-tetrahydrothieno[2.3-c]pyridine-3-carboxylate
  • Thieno[2,3-c]pyridine-3,6(5H)-dicarboxylic acid, 2-amino-4,7-dihydro-, 6-(1,1-dimethylethyl) 3-ethyl ester
  • 2-AMINO-6-BOC-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER
  • BOC-ETHYL 2-AMINO- 4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBOXYLATE
  • Ethyl 2-aMino-6-Boc-4,7-d...
  • 2-AMino-6-Boc-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxylic acid ethyl e
  • Ethyl 2-aMino-6-Boc-4,7-dihydro-5H-thieno[3,2-c]pyridine-3-carboxylate
  • Ethyl 6-Boc-2-amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3-carboxylate
  • 2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3,6-dicarboxylic acid 6-tert-butyl 3-ethyl ester
  • 2-amino-4,7-dihydro-5h-thieno(2,3-c)pyridine-3,6-dicarboxylic acid 6-tert-butyl 3-ethyl
  • 106278
  • 2-amino-5,7-dihydro-4H-thieno[2,3-c]pyridine-3,6-dicarboxylic acid O6-tert-butyl ester O3-ethyl ester
  • 6-tert-butyl 3-ethyl 2-aMino-4H,5H,6H,7H-thieno[2,3-c]pyridine-3,6-dicarboxylate
  • 2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTE
  • 2-amino-5,7-dihydro-4H-thieno[5,4-c]pyridine-3,6-dicarboxylic acid O6-tert-butyl O3-ethyl ester
  • O6-tert-butyl O3-ethyl 2-amino-5,7-dihydro-4H-thieno[5,4-c]pyridine-3,6-dicarboxylate
  • ST5408868
  • ZINC04287569
  • Ethyl 2-aMino-6-boc-4,7-dihydrothieno[2,3-c]pyridine-3(5H)-carboxylate, 97%
  • Ethyl2-amino-6-Boc-4,7-dihydrothieno[2,3-c]pyridine-3(5H)-carboxylate,97%
  • 2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER ISO 9001：2015 REACH
  • 2-Amino-4,7-Dihydro-5H-Thieno[2,3-C]Pyridine-3,6-Dicarboxyli...
  • 6-(tert-butyl) 3-ethyl 2-amino-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-3,6-dicarboxylate
  • 193537-14-3
  • C15H22N2O4S
  • CHIRAL CHEMICALS
  • Esters
  • Fused Ring Systems