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CARYOPHYLLENE OXIDE

Product Name
CARYOPHYLLENE OXIDE
CAS No.
1139-30-6
Chemical Name
CARYOPHYLLENE OXIDE
Synonyms
(-)-CARYOPHYLLENE OXIDE;(-)-EPOXYCARYOPHYLLENE;Caryophylene oxide;Caryophyllene epoxide;Caryophyllene oxyde;(-)-beta-Caryophyllene epoxide;caryophyleneoxide;CARYOPHYLLENEPOXID;5-oxatricyclo(8.20.0(4,6))dodecane,4,12,12-trimethyl-9-methylene-,(1r,4r,6r,1;0s)-
CBNumber
CB3199893
Molecular Formula
C15H24O
Formula Weight
220.35
MOL File
1139-30-6.mol
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CARYOPHYLLENE OXIDE Property

Melting point:
62-63 °C(lit.)
Boiling point:
301.3°C (rough estimate)
Density 
0.96
refractive index 
1.4956
FEMA 
4085 | BETA-CARYOPHYLLENE OXIDE
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Crystalline Powder
color 
White
Odor
at 100.00 %. sweet fresh dry woody spicy
Odor Type
woody
optical activity
[α]20/D 71±1°, c = 2% in chloroform
Water Solubility 
insoluble in water
JECFA Number
1575
BRN 
148213
LogP
4.57
EPA Substance Registry System
5-Oxatricyclo[8.2.0.04,6]dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)- (1139-30-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
26
WGK Germany 
2
RTECS 
RP5530000
1-10
HS Code 
29109000
Hazardous Substances Data
1139-30-6(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
91034
Product name
(?)-Caryophyllene oxide
Purity
analytical standard
Packaging
100mg
Price
$100
Updated
2024/03/01
Sigma-Aldrich
Product number
22076
Product name
(?)-Caryophyllene oxide
Purity
≥99.0% (sum of enantiomers, GC)
Packaging
1g
Price
$104
Updated
2024/03/01
Sigma-Aldrich
Product number
W408588
Product name
(−)-Caryophyllene oxide
Purity
natural (US), ≥95%, FG
Packaging
SAMPLE-K
Price
$56.2
Updated
2023/06/20
Sigma-Aldrich
Product number
W408588
Product name
(−)-Caryophyllene oxide
Purity
natural (US), ≥95%, FG
Packaging
100G
Price
$292
Updated
2023/06/20
Sigma-Aldrich
Product number
W408588
Product name
(−)-Caryophyllene oxide
Purity
natural (US), ≥95%, FG
Packaging
1KG
Price
$1010
Updated
2023/06/20
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CARYOPHYLLENE OXIDE Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Chemical Properties

Caryophyllene oxide which has a woody, slightly ambergris-like odor, can be prepared by treatment of ??-caryophyllene with organic peracids.

Chemical Properties

Colorless solid; sweet fruity aroma.

Occurrence

Reported found in Nepeta betonicifolia C.A. Meyer oil Turkey (39.20%), geranium rose-scented oil (Pelargonium spp.) Cuba (14.70%), melissa oil (9.99%), guava leaf oil Cuba (8.20%), etc.

Uses

β-Caryophyllene Epoxide, and its derivatives has shown to have microbial transformation and butyrylcholinesterase inhibitory activity. It is also the main active constituent of essential oils obtained from various plants, used for flavoring and fragrances.

Definition

ChEBI: A natural product found in Cupania cinerea.

Aroma threshold values

Medium strength odor, woody type.

Safety Profile

Low toxicity by ingestion and skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

Purify the oxide by TLC on silica gel with EtOAc/pet ether (b 60-80o) (15:85), and recrystallise it from MeOH or *C6H6. [NMR: Warnhoff Can J Chem 42 1664 1964, Ramage & Whitehead J Chem Soc 4336 1954, Beilstein 17 IV 392.]

CARYOPHYLLENE OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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CARYOPHYLLENE OXIDE Suppliers

Shanghai Luofa Biochemical Technology Co., Ltd.
Tel
021-51111890 15317326293
Email
sales@molnova.com
Country
China
ProdList
4195
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
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View Lastest Price from CARYOPHYLLENE OXIDE manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Caryophyllene Oxide 1139-30-6
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-12-02
Hebei Weibang Biotechnology Co., Ltd
Product
CARYOPHYLLENE OXIDE 1139-30-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 MT
Release date
2024-11-14
Shandong Deshang Chemical Co., Ltd.
Product
CARYOPHYLLENE OXIDE 1139-30-6
Price
US $16.00-10.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
10 tons
Release date
2024-06-19

1139-30-6, CARYOPHYLLENE OXIDERelated Search:


  • (-)-5-Oxatricyclo[8.2.0.0(4,6)]dodecane,4,12,12-trimethyl-9-methylene-, [1R-(1R*,4R*,6R*,10S*)]-
  • (-)-beta-Caryophyllene epoxide
  • caryophyleneoxide
  • Caryophyllene epoxide
  • Caryophyllene oxyde
  • caryophylleneepoxide
  • (1R,4R,6R,10S)-9-METHYLENE-4,12,12-TRIMETHYL-5-OXATRICYCLO[8.2.0.0(4,6)]DODECANE
  • (-)-EPOXYCARYOPHYLLENE
  • (-)-CARYOPHYLLENE OXIDE
  • CARYOPHYLLENE OXIDE
  • caryophylleneoxide,(1R,4R,6R,10S)-4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.0]4,6)]dodecane
  • 5-Oxatricyclo8.2.0.04,6dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-
  • (1R-(1R*,4R*,6R*,10S*))-4,12,12-Trimethyl-9-methylen-5-oxatricyclo(8.2.0.04,6)dodecan
  • CARYOPHYLLENEPOXID
  • (-)-Epoxycaryophyllene, (1R,4R,6R,10S)-9-Methylene-4,12,12-trimethyl-5-oxatricyclo[8.2.0.04,6]dodecane
  • (1R,4R,6R,10S)-4,12,12-Trimethyl-9-methylene-5-oxatricyclo[8.2.0.04,6]dodecane
  • (1R,5S,8R,11R)-4-Methylene-7,7,11-trimethyl-12-oxatricyclo[9.1.0.05,8]dodecane
  • (1β,4R,5R,9α)-4,11,11-Trimethyl-8-methylene-4,5-epoxybicyclo[7.2.0]undecane
  • (-)-Caryophyllene oxide,97%
  • (-)-CARYOPHYLLENE OXIDE 95%
  • CARYOPHYLLENE OXIDE TECH. 90%
  • CARYOPHYLLENE OXIDE 95+%
  • (-)-beta-caryophylleneepoxid
  • (-)-beta-caryophylleneepoxide
  • (-)-Epoxydihydrocaryophyllene
  • (1r-(1r*,4r*,6r*,10s*))-4,12,12-trimethyl-9-methylene-5-oxatricyclo(8.2.0.04,6)dodecane
  • (1r-(1r,4r,6r,10s))-4,12,12-trimethyl
  • (1r-(1r,4r,6r,10s))-4,12,12-trimethyl-9-methylene-5-oxatricyclo(8.2.0.04,6)dodecane
  • ,6r,10s)-
  • 0s)-
  • 4,11,11-Trimethyl-8-methylene-5-oxatricyclo(8.2.0.0(4,6))dodecane
  • 4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.]dodecane (caryophyllene oxide)
  • 4theta,6theta,10s)]-thet
  • 5-)xatricyclo[8.2.0.0(4,6))dodecane, 6,,11,11-trimethyl-2-methylene, [1R-(1R*,4R*,6R*,10S*)]-
  • 5-oxatricyclo(8.2.0.0(4,6))dodecane,4,12,12-trimethyl-9-methylene-,(1r-(1r*,4
  • 5-oxatricyclo(8.2.0.0(sup4,6))dodecane,4,12,12-trimethyl-9-methylene-,(1r,4r
  • 5-Oxatricyclo(8.2.0.0<sup>4,6</sup>)dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-
  • 5-oxatricyclo(8.20.0(4,6))dodecane,4,12,12-trimethyl-9-methylene-,(1r,4r,6r,1
  • 5-Oxatricyclo[8.2.0.0(4,6)-]dodecane, 4,12,12-trimethyl-9-methylene-, [1R-(1R*,4R*,6R*,10S*)]-
  • 5-oxatricyclo[8.2.0.04,6]dodecane,,12,12-trimethyl-3-methylene-[1r-
  • 6]dodecane,4,12,12-trimethyl-9-methylene-,[1R-(1R*,4R*,6R*,10S*)]-5-Oxatricyclo[8.2.0.04
  • 6]dodecane,4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.0[1theta-(1
  • 6r*,10s*))-r
  • beta-Caryophyllene oxide
  • beta-caryophylleneepoxide
  • beta-caryophylleneoxide
  • Caryophylene oxide
  • (-)-Caryophyllene oxide, 95% 10GR
  • CARYLOPHYLLENE OXIDE
  • (-)-CARYOPHYLLENE OXIDE, >= 99.0 % G
  • (-)-Caryophyllene oxide@100 μg/mL in Methanol
  • (-)-Caryophyllene oxide, 95%
  • Caryopyllene oxide
  • Caryophyllene oxide USP/EP/BP
  • β-Caryophyllene Epoxide
  • TIANFUCHEM--1139-30-6--High purity CARYOPHYLLENE OXIDE in stock
  • (-)-Caryophyllene oxide, 95%,
  • DXP 5648