ChemicalBook > CAS DataBase List > Caryophyllene oxide
Caryophyllene oxide
- Product Name
- Caryophyllene oxide
- CAS No.
- 1139-30-6
- Chemical Name
- Caryophyllene oxide
- Synonyms
- (-)-CARYOPHYLLENE OXIDE;(-)-EPOXYCARYOPHYLLENE;Caryophylene oxide;Caryophyllene epoxide;Caryophyllene oxyde;(-)-beta-Caryophyllene epoxide;caryophyleneoxide;CARYOPHYLLENEPOXID;5-oxatricyclo(8.20.0(4,6))dodecane,4,12,12-trimethyl-9-methylene-,(1r,4r,6r,1;0s)-
- CBNumber
- CB3199893
- Molecular Formula
- C15H24O
- Formula Weight
- 220.35
- MOL File
- 1139-30-6.mol
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Caryophyllene oxide Property
- Melting point:
- 62-63 °C(lit.)
- Boiling point:
- 301.3°C (rough estimate)
- Density
- 0.96
- refractive index
- 1.4956
- FEMA
- 4085 | BETA-CARYOPHYLLENE OXIDE
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Crystalline Powder
- color
- White
- Odor
- at 100.00 %. sweet fresh dry woody spicy
- Odor Type
- woody
- biological source
- synthetic
- optical activity
- [α]20/D 71±1°, c = 2% in chloroform
- Water Solubility
- insoluble in water
- JECFA Number
- 1575
- BRN
- 148213
- LogP
- 4.57
- EPA Substance Registry System
- 5-Oxatricyclo[8.2.0.04,6]dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)- (1139-30-6)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/38
- Safety Statements
- 26
- WGK Germany
- 2
- RTECS
- RP5530000
- F
- 1-10
- HS Code
- 29109000
- Hazardous Substances Data
- 1139-30-6(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- W509647
- Product name
- (−)-Caryophyllene oxide
- Purity
- 95%
- Packaging
- 1 unit
- Price
- $56.3
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- W509647
- Product name
- (−)-Caryophyllene oxide
- Purity
- 95%
- Packaging
- 1 unit
- Price
- $56.3
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- W408588
- Product name
- (−)-Caryophyllene oxide
- Purity
- natural (US), ≥95%, FG
- Packaging
- 1 unit
- Price
- $58
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- W408588
- Product name
- (−)-Caryophyllene oxide
- Purity
- natural (US), ≥95%, FG
- Packaging
- 1 unit
- Price
- $58
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- W408588
- Product name
- (−)-Caryophyllene oxide
- Purity
- natural (US), ≥95%, FG
- Packaging
- 100G
- Price
- $302
- Updated
- 2025/07/31
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Caryophyllene oxide Chemical Properties,Usage,Production
Chemical Properties
Caryophyllene oxide is a Colorless or white crystalline powder that has a woody, slightly ambergris-like odor, can be prepared by treatment of β-caryophyllene with organic peracids.
Occurrence
Reported found in Nepeta betonicifolia C.A. Meyer oil Turkey (39.20%), geranium rose-scented oil (Pelargonium spp.) Cuba (14.70%), melissa oil (9.99%), guava leaf oil Cuba (8.20%), etc.
Uses
β-Caryophyllene Epoxide, and its derivatives has shown to have microbial transformation and butyrylcholinesterase inhibitory activity. It is also the main active constituent of essential oils obtained from various plants, used for flavoring and fragrances.
Definition
ChEBI: Caryophyllene oxide is an epoxide，a natural product found in Cupania cinerea. It has a role as a metabolite.
Aroma threshold values
Medium strength odor, woody type.
Biological Activity
β-caryophyllene oxide is a potent anti-cancer agent which also exerts antioxidant, anti-inflammatory, and antiviral properties. It is a strong inhibitor of drug-metabolizing enzyme cytochromes P4503A (CYP3A) activities both in r at and human hepatic microsomes. BCPO also exerts analgesic, antifungal, antibacterial, and genoprotective activities.
Safety Profile
Low toxicity by ingestion and skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods
Purify the oxide by TLC on silica gel with EtOAc/pet ether (b 60-80o) (15:85), and recrystallise it from MeOH or *C6H6. [NMR: Warnhoff Can J Chem 42 1664 1964, Ramage & Whitehead J Chem Soc 4336 1954, Beilstein 17 IV 392.]
Caryophyllene oxide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Caryophyllene oxide manufacturers
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- CARYOPHYLLENE OXIDE 1139-30-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100 MT
- Release date
- 2024-11-14
Hebei Zhuanglai Chemical Trading Co Ltd
- Product
- Caryophyllene Oxide 1139-30-6
- Price
- US $150.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2024-12-02
Shandong Deshang Chemical Co., Ltd.
- Product
- CARYOPHYLLENE OXIDE 1139-30-6
- Price
- US $16.00-10.00/kg
- Min. Order
- 1kg
- Purity
- 99.99%
- Supply Ability
- 10 tons
- Release date
- 2024-06-19
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