ChemicalBook > CAS DataBase List > CARYOPHYLLENE OXIDE

CARYOPHYLLENE OXIDE

Product Name
CARYOPHYLLENE OXIDE
CAS No.
1139-30-6
Chemical Name
CARYOPHYLLENE OXIDE
Synonyms
(-)-CARYOPHYLLENE OXIDE;(-)-EPOXYCARYOPHYLLENE;Caryophylene oxide;Caryophyllene epoxide;Caryophyllene oxyde;(-)-beta-Caryophyllene epoxide;caryophyleneoxide;CARYOPHYLLENEPOXID;5-oxatricyclo(8.20.0(4,6))dodecane,4,12,12-trimethyl-9-methylene-,(1r,4r,6r,1;0s)-
CBNumber
CB3199893
Molecular Formula
C15H24O
Formula Weight
220.35
MOL File
1139-30-6.mol
More
Less

CARYOPHYLLENE OXIDE Property

Melting point:
62-63 °C(lit.)
Boiling point:
301.3°C (rough estimate)
Density 
0.96
refractive index 
1.4956
FEMA 
4085 | BETA-CARYOPHYLLENE OXIDE
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Crystalline Powder
color 
White
Odor
at 100.00 %. sweet fresh dry woody spicy
Odor Type
woody
optical activity
[α]20/D 71±1°, c = 2% in chloroform
Water Solubility 
insoluble in water
JECFA Number
1575
BRN 
148213
LogP
4.57
EPA Substance Registry System
5-Oxatricyclo[8.2.0.04,6]dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)- (1139-30-6)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
26
WGK Germany 
2
RTECS 
RP5530000
1-10
HS Code 
29109000
Hazardous Substances Data
1139-30-6(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
91034
Product name
(?)-Caryophyllene oxide
Purity
analytical standard
Packaging
100mg
Price
$100
Updated
2024/03/01
Sigma-Aldrich
Product number
22076
Product name
(?)-Caryophyllene oxide
Purity
≥99.0% (sum of enantiomers, GC)
Packaging
1g
Price
$104
Updated
2024/03/01
Sigma-Aldrich
Product number
W408588
Product name
(−)-Caryophyllene oxide
Purity
natural (US), ≥95%, FG
Packaging
SAMPLE-K
Price
$56.2
Updated
2023/06/20
Sigma-Aldrich
Product number
W408588
Product name
(−)-Caryophyllene oxide
Purity
natural (US), ≥95%, FG
Packaging
100G
Price
$292
Updated
2023/06/20
Sigma-Aldrich
Product number
W408588
Product name
(−)-Caryophyllene oxide
Purity
natural (US), ≥95%, FG
Packaging
1KG
Price
$1010
Updated
2023/06/20
More
Less

CARYOPHYLLENE OXIDE Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Chemical Properties

Caryophyllene oxide which has a woody, slightly ambergris-like odor, can be prepared by treatment of ??-caryophyllene with organic peracids.

Chemical Properties

Colorless solid; sweet fruity aroma.

Occurrence

Reported found in Nepeta betonicifolia C.A. Meyer oil Turkey (39.20%), geranium rose-scented oil (Pelargonium spp.) Cuba (14.70%), melissa oil (9.99%), guava leaf oil Cuba (8.20%), etc.

Uses

β-Caryophyllene Epoxide, and its derivatives has shown to have microbial transformation and butyrylcholinesterase inhibitory activity. It is also the main active constituent of essential oils obtained from various plants, used for flavoring and fragrances.

Definition

ChEBI: A natural product found in Cupania cinerea.

Aroma threshold values

Medium strength odor, woody type.

Safety Profile

Low toxicity by ingestion and skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

Purify the oxide by TLC on silica gel with EtOAc/pet ether (b 60-80o) (15:85), and recrystallise it from MeOH or *C6H6. [NMR: Warnhoff Can J Chem 42 1664 1964, Ramage & Whitehead J Chem Soc 4336 1954, Beilstein 17 IV 392.]

CARYOPHYLLENE OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

CARYOPHYLLENE OXIDE Suppliers

Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
More
Less

View Lastest Price from CARYOPHYLLENE OXIDE manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
CARYOPHYLLENE OXIDE 1139-30-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 MT
Release date
2024-11-14
Shandong Deshang Chemical Co., Ltd.
Product
CARYOPHYLLENE OXIDE 1139-30-6
Price
US $16.00-10.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
10 tons
Release date
2024-06-19
Shaanxi Dideu Medichem Co. Ltd
Product
CARYOPHYLLENE OXIDE 1139-30-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
10 tons
Release date
2024-08-05

1139-30-6, CARYOPHYLLENE OXIDERelated Search:


  • (-)-5-Oxatricyclo[8.2.0.0(4,6)]dodecane,4,12,12-trimethyl-9-methylene-, [1R-(1R*,4R*,6R*,10S*)]-
  • (-)-beta-Caryophyllene epoxide
  • caryophyleneoxide
  • Caryophyllene epoxide
  • Caryophyllene oxyde
  • caryophylleneepoxide
  • (1R,4R,6R,10S)-9-METHYLENE-4,12,12-TRIMETHYL-5-OXATRICYCLO[8.2.0.0(4,6)]DODECANE
  • (-)-EPOXYCARYOPHYLLENE
  • (-)-CARYOPHYLLENE OXIDE
  • CARYOPHYLLENE OXIDE
  • caryophylleneoxide,(1R,4R,6R,10S)-4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.0]4,6)]dodecane
  • 5-Oxatricyclo8.2.0.04,6dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-
  • (1R-(1R*,4R*,6R*,10S*))-4,12,12-Trimethyl-9-methylen-5-oxatricyclo(8.2.0.04,6)dodecan
  • CARYOPHYLLENEPOXID
  • (-)-Epoxycaryophyllene, (1R,4R,6R,10S)-9-Methylene-4,12,12-trimethyl-5-oxatricyclo[8.2.0.04,6]dodecane
  • (1R,4R,6R,10S)-4,12,12-Trimethyl-9-methylene-5-oxatricyclo[8.2.0.04,6]dodecane
  • (1R,5S,8R,11R)-4-Methylene-7,7,11-trimethyl-12-oxatricyclo[9.1.0.05,8]dodecane
  • (1β,4R,5R,9α)-4,11,11-Trimethyl-8-methylene-4,5-epoxybicyclo[7.2.0]undecane
  • (-)-Caryophyllene oxide,97%
  • (-)-CARYOPHYLLENE OXIDE 95%
  • CARYOPHYLLENE OXIDE TECH. 90%
  • CARYOPHYLLENE OXIDE 95+%
  • (-)-beta-caryophylleneepoxid
  • (-)-beta-caryophylleneepoxide
  • (-)-Epoxydihydrocaryophyllene
  • (1r-(1r*,4r*,6r*,10s*))-4,12,12-trimethyl-9-methylene-5-oxatricyclo(8.2.0.04,6)dodecane
  • (1r-(1r,4r,6r,10s))-4,12,12-trimethyl
  • (1r-(1r,4r,6r,10s))-4,12,12-trimethyl-9-methylene-5-oxatricyclo(8.2.0.04,6)dodecane
  • ,6r,10s)-
  • 0s)-
  • 4,11,11-Trimethyl-8-methylene-5-oxatricyclo(8.2.0.0(4,6))dodecane
  • 4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.]dodecane (caryophyllene oxide)
  • 4theta,6theta,10s)]-thet
  • 5-)xatricyclo[8.2.0.0(4,6))dodecane, 6,,11,11-trimethyl-2-methylene, [1R-(1R*,4R*,6R*,10S*)]-
  • 5-oxatricyclo(8.2.0.0(4,6))dodecane,4,12,12-trimethyl-9-methylene-,(1r-(1r*,4
  • 5-oxatricyclo(8.2.0.0(sup4,6))dodecane,4,12,12-trimethyl-9-methylene-,(1r,4r
  • 5-Oxatricyclo(8.2.0.0<sup>4,6</sup>)dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-
  • 5-oxatricyclo(8.20.0(4,6))dodecane,4,12,12-trimethyl-9-methylene-,(1r,4r,6r,1
  • 5-Oxatricyclo[8.2.0.0(4,6)-]dodecane, 4,12,12-trimethyl-9-methylene-, [1R-(1R*,4R*,6R*,10S*)]-
  • 5-oxatricyclo[8.2.0.04,6]dodecane,,12,12-trimethyl-3-methylene-[1r-
  • 6]dodecane,4,12,12-trimethyl-9-methylene-,[1R-(1R*,4R*,6R*,10S*)]-5-Oxatricyclo[8.2.0.04
  • 6]dodecane,4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.0[1theta-(1
  • 6r*,10s*))-r
  • beta-Caryophyllene oxide
  • beta-caryophylleneepoxide
  • beta-caryophylleneoxide
  • Caryophylene oxide
  • (-)-Caryophyllene oxide, 95% 10GR
  • CARYLOPHYLLENE OXIDE
  • (-)-CARYOPHYLLENE OXIDE, >= 99.0 % G
  • (-)-Caryophyllene oxide@100 μg/mL in Methanol
  • (-)-Caryophyllene oxide, 95%
  • Caryopyllene oxide
  • Caryophyllene oxide USP/EP/BP
  • β-Caryophyllene Epoxide
  • TIANFUCHEM--1139-30-6--High purity CARYOPHYLLENE OXIDE in stock
  • (-)-Caryophyllene oxide, 95%,
  • DXP 5648