ChemicalBook > CAS DataBase List > enniatin A1
enniatin A1
- Product Name
- enniatin A1
- CAS No.
- 4530-21-6
- Chemical Name
- enniatin A1
- Synonyms
- enniatin A1;2-(N-Methyl-L-valine)enniatin A;(3S,6R,9S,12R,15S,18R)-3,9-bis[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,15,18-tetra(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl]
- CBNumber
- CB32079106
- Molecular Formula
- C35H61N3O9
- Formula Weight
- 667.879
- MOL File
- 4530-21-6.mol
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enniatin A1 Property
- Melting point:
- 116-117 °C
- Boiling point:
- 840.5±65.0 °C(Predicted)
- Density
- 1.027±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: soluble10mg/mL
- form
- White to off-white crystalline solid.
- pka
- -1.44±0.70(Predicted)
- biological source
- Gnomonia errabunda
- InChIKey
- OWUREPXBPJFMOK-UHFFFAOYSA-N
- SMILES
- O1C(C(C)C)C(N(C)C(C(C)CC)C(OC(C(C)C)C(N(C)C(C(C)CC)C(OC(C(C)C)C(N(C)C(C(C)C)C1=O)=O)=O)=O)=O)=O
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- E5161
- Product name
- Enniatin A1
- Purity
- from Gnomonia errabunda, ≥95% (HPLC)
- Packaging
- 1mg
- Price
- $217
- Updated
- 2025/07/31
Cayman Chemical
- Product number
- 17457
- Product name
- Enniatin A1
- Purity
- ≥99%
- Packaging
- 1mg
- Price
- $166
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17457
- Product name
- Enniatin A1
- Purity
- ≥99%
- Packaging
- 5mg
- Price
- $698
- Updated
- 2024/03/01
TRC
- Product number
- E555995
- Product name
- Enniatin A1
- Packaging
- 10mg
- Price
- $1630
- Updated
- 2021/12/16
TRC
- Product number
- E555995
- Product name
- Enniatin A1
- Packaging
- 1mg
- Price
- $175
- Updated
- 2021/12/16
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enniatin A1 Chemical Properties,Usage,Production
Uses
Enniatins are a family of depsipeptide ionophores, produced several Fusarium species. More recently, the effects of the ennitins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumour action have received more focus. Enniatin A1 is one of four major analogues of the enniatin complex and has previously not been available for investigation.
Uses
Enniatins are a family of depsipeptide ionophores produced by several Fusarium species. Recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin A1 is one of four major analogues of the enniatin complex .
Uses
Enniatin A1 is a mycotoxin capable of creating negative CNS effects due to their ability to cross the blod-brain barrier. Secondary metabolite of microbes, it is associated with mold, moisture damage and asthma development.
Definition
ChEBI: An enniatin obtained from formal cyclocondensation of one N-[(2R)-2-hydroxy-3-methylbutanoyl]-N-methyl-L-valine and two N-[(2R)-2-hydroxy-3-methylbu anoyl]-N-methyl-L-isoleucine units.
Biochem/physiol Actions
Enniatins are a group of cyclohexadepsipeptide mycotoxins produced by Gnomonia errabuda and several Fusaria species, with phytotoxic, antibiotic, and insecticidal activities. Enniatins function as ionophors by their incorporation into the cellular membrane to form dimeric structures that transport monovalent ions across the membrane (especially the mitochondrial membranes) affecting oxidative phosphorylation uncoupling. It has been demonstrated that enniatins have a cytotoxic effect on human cancer cells. Furthermore, incubation of H4IIE hepatoma cells with enniatins strongly diminished phosphorylation of the ERK (p44/p42).
IC 50
ERK
enniatin A1 Preparation Products And Raw materials
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Preparation Products
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View Lastest Price from enniatin A1 manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- enniatin A1 4530-21-6
- Price
- US $25.00-11.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2024-08-12