ChemicalBook > CAS DataBase List > Lecirelin

Lecirelin

Product Name
Lecirelin
CAS No.
61012-19-9
Chemical Name
Lecirelin
Synonyms
LEC;LECIRELIN;Supergestran;Lecirelin, BR;SUPERGESTRAN(TM);Lecirelin Acetate;(D-TLE6)-LEUPROLIDE;DalMarelin Acetate;LECIRELIN USP/EP/BP;(D-TLE6)-LEUPRORELIN
CBNumber
CB3209815
Molecular Formula
C59H84N16O12
Formula Weight
1209.42
MOL File
61012-19-9.mol
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Lecirelin Property

Density 
1.44
storage temp. 
Store at -20°C
solubility 
DMSO : 12.1 mg/mL (10.00 mM)
pka
9.82±0.15(Predicted)
InChIKey
XJWIEWPGHRSZJM-JUAATNMYNA-N
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

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N-Bromosuccinimide Price

TRC
Product number
L320053
Product name
Lecirelin
Packaging
5mg
Price
$70
Updated
2021/12/16
Usbiological
Product number
453607
Product name
Lecirelin
Packaging
5mg
Price
$340
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD109660
Product name
(Des-Gly10, tBu-D-Gly6,Pro-NHEt 9)-LHRH trifluoroacetate salt Pyr-His-Trp-Ser-Tyr-tBu-D-Gly-Leu-Arg-Pro-NHEt trifluoroacetate salt
Packaging
10mg
Price
$228
Updated
2021/12/16
ChemScene
Product number
CS-5785
Product name
Lecirelin
Purity
99.80%
Packaging
10mg
Price
$240
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD109861
Product name
(Des-Gly10, tBu-D-Gly6,Pro-NHEt 9)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-tBu-D-Gly-Leu-Arg-Pro-NHEt acetate salt
Packaging
10mg
Price
$285
Updated
2021/12/16
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Lecirelin Chemical Properties,Usage,Production

Uses

Mammalian LHRHa containing Supergestran was used to stimulate the spermiation of tench males. Half dose of lecirelin was almost equally effective to induce the disappearance of the dominant follicle at Day 6 to 7 of the estrous cycle in three GnRH analogs of cattle.

Definition

Lecirelin, a synthetic gonadotropin-releasing hormone (GnRH) analog, acts as a GnRH agonist. Lecirelin is widely used for the research of bovine ovarian follicular cysts. lecithin and buserelin, two nonapeptides, are used as the acetate. Lecirelin differs by substitution of D-tertiary leucine for glycine at position 6 and the replacement of glycine by ethylamide at position 10. Buserelin has a D-serine at position 6 and ethylamide at position 10.

in vitro

Lecirelin (2.07 μM) significantly increases the tension and frequency of contractions in preovulatory follicles (PF), small follicular cysts (FC-S), and large follicular cysts (FC-L). Lecirelin increases the strips from preovulatory follicles contract significantly more than strips from cysts.

References

[1] Picard-Hagen N, et al. Effect of gonadorelin, lecirelin, and buserelin on LH surge, ovulation, and progesterone in cattle. Theriogenology, 2015; 84: 177-183.

Lecirelin Preparation Products And Raw materials

Raw materials

Preparation Products

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Lecirelin Suppliers

China 103 France 1 Germany 2 India 3 The Netherlands 1 United Kingdom 4 United States 13 USA 1 Global 128
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View Lastest Price from Lecirelin manufacturers

Wuhan Cell Pharmaceutical Co., Ltd
Product
Lecirelin 61012-19-9
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2023-04-07
Shanghai Getian Industrial Co., LTD
Product
Lecirelin 61012-19-9
Price
US $27.00/box
Min. Order
1box
Purity
99%
Supply Ability
20000box
Release date
2024-04-19
Nantong Guangyuan Chemicl Co,Ltd
Product
Lecirelin 61012-19-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-11-15

61012-19-9, LecirelinRelated Search:

GRF (1-44) (HUMAN) ARG-LYS-GLU-VAL-TYR ACETATE SALT CRF(Ovine)Trifluoroacetate Endothelin-1 (human, porcine) Terlipressin acetate Liraglutide Ornipressin Triptorelin Teriparatide acetate Amyloid β-Peptide (1-42) (human) CRF (HUMAN, RAT) Vasopressin Abarelix FERTIRELIN Octreotide Leuprorelin Lecirelin PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-NHET

  • SUPERGESTRAN(TM)
  • PYR-HIS-TRP-SER-TYR-TBU-D-GLY-LEU-ARG-PRO-NHET
  • Lecirelin(6-(3-methyl-D-valine)-9-(N-ethyl-L-prolynamide)-10-deglycinamide)
  • (DES-GLY10,TBU-D-GLY6,PRO-NHET9)-LHRH
  • (D-TLE6)-LEUPROLIDE
  • (D-TLE6)-LEUPRORELIN
  • [D-TLE6,PRO-NHET9]-LHRH
  • GLP-HIS-TRP-SER-TYR-TLE-LEU-ARG-PRO-NHET
  • LECIRELIN
  • (Des-Gly10,tBu-D-Gly6,Pro-NHEt9)-LHRH (D-Tle6)-Leuprolide, (D-Tle6)-Leuprorelin, Lecirelin
  • (D-Tle6)-Leuprolide, (D-Tle6)-Leuprorelin, Lecirelin
  • 6-(3-Methyl-D-valine)-9-(N-ethyl-L-prolinamide)-10-deglycinamide-luteinizing hormone-releasing factor (pig)
  • Supergestran
  • Lecirelin (Dalmarelin) Acetate
  • LECIRELIN (DALMARELIN) ACETATE
  • Lecirelin, (D-Tle6)-Leuprolide, (D-Tle6)-Leuprorelin, DalMarelin
  • Lecirelin Acetate
  • DalMarelin Acetate
  • 1-9-LuteinizinghorMone-releasing factor (swine),6-(3-Methyl-D-valine)-9-(N-ethyl-L-prolinaMide)-
  • Lecirelin, BR
  • (Des-Gly10, tBu-D-Gly6,Pro-NHEt 9)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-tBu-D-Gly-Leu-Arg-Pro-NHEt acetate salt
  • (Des-Gly10, tBu-D-Gly6,Pro-NHEt 9)-LHRH trifluoroacetate salt Pyr-His-Trp-Ser-Tyr-tBu-D-Gly-Leu-Arg-Pro-NHEt trifluoroacetate salt
  • LECIRELIN USP/EP/BP
  • Lecirelin/Supergestran
  • (Des-Gly??,tBu-D-Gly?,Pro-NHEt?)-LHRH trifluoroacetate salt
  • LEC
  • 61012-19-9
  • C59H84N16O12
  • C59H84N16O12xC2HF3O2
  • C59H84N16O12xC2H4O2
  • 61012-19-9