ChemicalBook > CAS DataBase List > (R)-(+)-1-(1-Naphthyl)ethylamine

(R)-(+)-1-(1-Naphthyl)ethylamine

Product Name
(R)-(+)-1-(1-Naphthyl)ethylamine
CAS No.
3886-70-2
Chemical Name
(R)-(+)-1-(1-Naphthyl)ethylamine
Synonyms
(R)-1-(1-NAPHTHYL)ETHYLAMINE;(R)-1-(NAPHTHALEN-1-YL)ETHANAMINE;CINACALCET intermediate;C12Hj3N;(R)-(+)-ALPH;Cinacalcet-21;RNEA IMPURITY;R-Napthylethylamine;Cinacalce Impurity A;Cinacalcet Impurity A
CBNumber
CB3210204
Molecular Formula
C12H13N
Formula Weight
171.24
MOL File
3886-70-2.mol
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(R)-(+)-1-(1-Naphthyl)ethylamine Property

Melting point:
135-136 °C
alpha 
60 º (c=2, CH3OH)
Boiling point:
153 °C11 mm Hg(lit.)
Density 
1.067 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.623(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form 
Liquid
pka
9.26±0.40(Predicted)
color 
brown
Specific Gravity
1.07
optical activity
[α]20/D +55°, c = 2 in ethanol
Water Solubility 
Soluble in water (<10/l).
Sensitive 
Air Sensitive
BRN 
2208025
Stability:
Stable. Air-sensitive. Incompatible with acids, oxidizing agents, acid anhydrides, chloroformates, acid chlorides.
InChIKey
RTCUCQWIICFPOD-SECBINFHSA-N
CAS DataBase Reference
3886-70-2(CAS DataBase Reference)
EPA Substance Registry System
1-Naphthalenemethanamine, .alpha.-methyl-, (.alpha.R)- (3886-70-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
2735
WGK Germany 
3
RTECS 
QJ6963000
F 
10-34
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29211990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
237442
Product name
(R)-(+)-1-(1-Naphthyl)ethylamine
Purity
≥99%
Packaging
1g
Price
$66.5
Updated
2024/03/01
Sigma-Aldrich
Product number
237442
Product name
(R)-(+)-1-(1-Naphthyl)ethylamine
Purity
≥99%
Packaging
5g
Price
$148
Updated
2024/03/01
TCI Chemical
Product number
N0482
Product name
(R)-(+)-1-(1-Naphthyl)ethylamine
Purity
>99.0%(GC)
Packaging
1g
Price
$43
Updated
2024/03/01
TCI Chemical
Product number
N0482
Product name
(R)-(+)-1-(1-Naphthyl)ethylamine
Purity
>99.0%(GC)
Packaging
5g
Price
$126
Updated
2024/03/01
Alfa Aesar
Product number
A16918
Product name
(R)-(+)-1-(1-Naphthyl)ethylamine, 99%
Packaging
5g
Price
$133.65
Updated
2024/03/01
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(R)-(+)-1-(1-Naphthyl)ethylamine Chemical Properties,Usage,Production

Description

(R)-(+)-1-(1-Naphthyl)ethylamine is a reagent used in the formation of isolated acids via salt formation. It is also a raw material for the synthesis of (R)-1-(1-Naphthyl)ethyl isocyanate. In materials research, the use of Reflectance Absorption Infrared Spectroscopy (RAIRS) can be used to study the structure, bonding and orientation of R-1- nea and (S)-(-)-1-(2-naphthyl)ethylamine (S-2- nea) on Pd(1 1 1).

Chemical Properties

Colorless to light yellow liqui

Uses

(R)-(+)-1-(1-Naphthyl)ethylamine is used in chiral synthesis in organic reactions including the synthesis of β-amino acids and the enantioselective of ketones to nitroolefins.

Uses

It is used in chiral synthesis in organic reactions including the synthesis of β-amino acids and the enantioselective of ketones to nitroolefins. Also used as absolute configuration of primary amines determined using chiral (2-nitrophenyl)proline amides and H NMR.

Application

Absolute configuration of primary amines determined using chiral (2-nitrophenyl)proline amides and 1H NMR.

General Description

(R)-(+)-1-(1-Naphthyl)ethylamine is a chiral derivatization reagent useful for all gas chromatography (GC) applications in the chiral field. It is specially selected to meet the requirements for derivatization reagents for enantiomeric excess determinations.

Solubility in organics

(R)-(+)-1-(1-Naphthyl)ethylamine is soluble in chloroform and ethanol. Insoluble in water.

Purification Methods

Purify the amine by distillation in a good vacuum. [Mori et al. Tetrahedron 37 1343 1981, cf Wilson in Topics Stereochem (Allinger and Eliel eds) v o l 6 135 1971, Fredga et al. Acta Chem Scand 11 1609 1957.] The hydrochlorides crystallise from H2O [] D 18 ±3.9o (c 3, H2O), and the sulfates recrystallise from H2O as tetrahydrates m 230-232o. The RS-amine has b 153o/11mm, 156o/15mm, 183.5o/41mm [Blicke & Maxwell J Am Chem Soc 6 1 1780 1939]. [Beilstein 12 III 3111.]

(R)-(+)-1-(1-Naphthyl)ethylamine Preparation Products And Raw materials

Raw materials

D-Phenylglycinol 1-Naphthaldehyde

Preparation Products

1R，3R-chrysanthemic acid
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View Lastest Price from (R)-(+)-1-(1-Naphthyl)ethylamine manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
(R)-(+)-1-(1-Naphthyl)ethylamine 3886-70-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-26
WUHAN FORTUNA CHEMICAL CO., LTD
Product
(R)-(+)-1-(1-Naphthyl)ethylamine 3886-70-2
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
10000KGS
Release date
2021-11-08
hebei hongtan Biotechnology Co., Ltd
Product
(R)-(+)-1-(1-Naphthyl)ethylamine 3886-70-2
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-05-14

3886-70-2, (R)-(+)-1-(1-Naphthyl)ethylamineRelated Search:

Diethylamine Diethylstilbestrol Etamsylate Triethylamine hydrochloride 1-(1-NAPHTHYL)-2-THIOUREA Ethambutol Ethylamine L-1-Phenylethylamine Triethylamine (1R,2R)-(-)-1,2-Diaminocyclohexane (1S,2R)-2-Amino-1,2-diphenylethanol (S)-Cinacalcet hydrochloride Cinacalcet (R)-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl]Methyl]-1-naphthaleneMethaneaMine Hydrochloride Cinacalcet IMpurity 9 Cinacalcet IMpurity ent-Cinacalcet Hydrochloride (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoroMethyl)phenyl)propan-1-aMine

  • (R) 1-(1-NAPTHYL)ETHYLAMINE
  • (R)-(+)-1-(1-NAPHTHYL)ETHYLAMINE
  • (R)-1-(1-NAPHTHYL)ETHYLAMINE
  • (R)-1-(NAPHTHALEN-1-YL)ETHANAMINE
  • (R)-(+)-1-(NAPHTHYL)ETHYLAMINE
  • (R)-(+)-A-(1-NAPHTHYL)ETHYLAMINE
  • (R)-(+)-ALPHA-(1-AMINOETHYL)NAPHTHALENE
  • (R)-(+)-ALPHA-(1-NAPHTHYL)ETHYLAMINE
  • D-A-(1-NAPHTHYL)ETHYLAMINE
  • (+)-1-[(R)-1-Aminoethyl]naphthalene
  • (1R)-1-(1-Naphthyl)ethanamine
  • (R)-α-Methylnaphthalene-1-methanamine
  • (αR)-α-(1-Naphthyl)ethanamine
  • [R,(+)]-α-Methyl-1-naphthalenemethanamine
  • 1-Naphthalenemethanamine, alpha-methyl-, (R)-
  • (theta)-1-naphthalenemethanamine
  • Cinacalcet Intermediate 3
  • (R)-(+)-alpha-(Naphthalen-1-yl)ethanaMine
  • (R)-(+)-ALPHA-(1-AMINOETHYL)NAPHT
  • (1R)-(+)-1-(Naphth-1-yl)ethylamine
  • (R)-(+)-alpha-(1-Naphthyl)ethylaMine, 99+% 1GR
  • (R)-1-(naphthalene-1-yl)ethanaMine
  • (R)-(+)-1-(1-Naphthyl)ethylaMine SynonyMs R-(+)-alpha-(1-Naphthyl)ethylaMine
  • (1R)-1-(naphthalen-1-yl)ethan-1-amine
  • Cinacalcet Impurity A
  • (R)-(+)-1-(1-phthyl)ethylamine
  • (R)-1-(1-naphthyl)ethylamine,99%e.e.
  • Cinacalce Impurity A
  • R-NAPHTHALENEYL METHYL-1-PHENYLETHYLAMINE
  • (1R)-(1-NAPHTHALEN-1-YL)ETHANAMINE
  • (theta)-1-naphthalenemethanamin
  • (R)-(+)-α-Methyl-1-naphthalenemethylamine
  • R-PLUS-A-1-NAPHTHYL-ETHYLAMINE
  • (R)-(+)-1-(1-NAPHTHYL)ETHYLAMINE 99%
  • (R)-(+)-1-(Napthyl)ethylamine, 99%
  • (R)-(+)-alpha-(1-Naphthyl)ethylamine, 99+%
  • 1-Naphthalenemethanamine, .alpha.-methyl-, (.alpha.R)-
  • (R)-(+)-1-(Naphth-1-yl)ethylamine
  • (R)-(+)-1-(1-Naphthyl)ethylamine, ChiPros 99+%, ee 98+%
  • (R)-(+)-ALPH
  • (R)-(+)-α-(1-Naphthyl)ethylamine, 99+%
  • (R)-1-(Naphthalen-1-yl)ethanamine HCl
  • R-(+)-NAPHTHYLETHYLAMINE
  • (R)- (+)--(1-NAPHTHYL) ETHYLAMINE 98%
  • R-Napthylethylamine
  • CINACALCET intermediate
  • (R)-(+)-1-(1-Naphthyl)ethylami
  • Cinacalcet-21
  • (R)-(+)-1-(1-NaphthyL
  • (R)-(+)-1-(1-Naphthyl)ethylamine&gt
  • (R)-(+)-1-(1-Naphthyl)ethylamine Cinacalcet Impurity A
  • 1-Naphthalenemethanamine, α-methyl-, (αR)-
  • (R)-(+)-α-(1-Naphthyl)ethylamine
  • (R)-(+)-1-(1-Naphthyl)ethylamine ISO 9001：2015 REACH
  • (R)-1-(Naphthalen-1-yl)ethanamine (Cinacalcet Impurity)
  • Cinacalcet Impurity A (Cinacalcet Amine Impurity)
  • Cinacalcet Impurity AQ: What is Cinacalcet Impurity A Q: What is the CAS Number of Cinacalcet Impurity A Q: What is the storage condition of Cinacalcet Impurity A Q: What are the applications of Cinacalcet Impurity A
  • (R)-1-(1-Naphthalenyl)ethylamine