Chloromethyl isobutyrate

Product Name: Chloromethyl isobutyrate
CAS No.: 61644-18-6
Chemical Name: Chloromethyl isobutyrate
Synonyms: Chloromethyl isobutyrate;(Isobutyryloxy)methyl chloride;Chloromethyl 2-methylpropionate;Chloromethyl 2-methylpropanoate;Propanoicacid, 2-methyl-, chloromethyl ester
CBNumber: CB32123320
Molecular Formula: C5H9ClO2
Formula Weight: 136.58
MOL File: 61644-18-6.mol

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Chloromethyl isobutyrate Property

Boiling point:: 124.6±13.0 °C(Predicted)
Density: 1.081±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform (Sparingly), Methanol (Slightly)
form: Oil
color: Colourless
InChI: InChI=1S/C5H9ClO2/c1-4(2)5(7)8-3-6/h4H,3H2,1-2H3
InChIKey: ILUWVORABZTBIU-UHFFFAOYSA-N
SMILES: C(OCCl)(=O)C(C)C

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Safety

RIDADR: UN2920
HazardClass: 8, 3
HS Code: 2915907098

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: C381950
Product name: ChloromethylIsobutyrate
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC160496
Product name: Chloromethyl Isobutyrate
Packaging: 5G
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC160496
Product name: Chloromethyl Isobutyrate
Packaging: 10g
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC160496
Product name: Chloromethyl Isobutyrate
Packaging: 25g
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC160496
Product name: Chloromethyl Isobutyrate
Packaging: 50g
Price: $250
Updated: 2021/12/16

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Chloromethyl isobutyrate Chemical Properties,Usage,Production

Synthesis

49715-04-0

79-31-2

61644-18-6

Step A: Synthesis of chloromethyl isobutyrate To a solution of isobutyric acid (0.600 mL, 6.47 mmol) in dichloromethane (DCM, 6 mL) was added sodium bicarbonate (2092 mg, 24.91 mmol), tetrabutylammonium hydrogensulfate (220 mg, 0.65 mmol), and water (6 mL) in that order. Chloromethyl chloroformate (0.767 mL, 7.44 mmol) was added slowly at room temperature with rapid stirring. After addition, the reaction mixture was continued to stir at room temperature overnight. Upon completion of the reaction, the reaction mixture was diluted with dichloromethane (10 mL) and subsequently washed with water (2 x 10 mL). The organic phase was dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated to afford the crude chloromethyl isobutyrate (746 mg, 84% yield). The product was used directly in the next step of the reaction without further purification. 1H NMR (500 MHz, CDCl3) δ ppm: 1.17 (m, 6H), 2.62 (m, 1H), 5.72 (s, 2H).

References

[1] Patent: WO2015/67923, 2015, A1. Location in patent: Paragraph 00072; 00073; 00074
[2] Patent: US2018/37550, 2018, A1. Location in patent: Paragraph 0081-0083
[3] Patent: WO2014/4884, 2014, A1. Location in patent: Paragraph 00310-00311; 00322

Chloromethyl isobutyrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Chloromethyl isobutyrate Suppliers

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View Lastest Price from Chloromethyl isobutyrate manufacturers

Career Henan Chemical Co

Product: Chloromethyl isobutyrate 61644-18-6
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-09

61644-18-6, Chloromethyl isobutyrateRelated Search:

CIS-3-HEXENYL ISOBUTYRATE Maltol isobutyrate Isobutyramide Methyl isobutyrylacetate Ethyl isobutyrylacetate ChloroMethyl Methyl Carbonate Chloromethyl chlorosulfate Chloromethyl isopropyl carbonate Methyl pentafluoropropionate

(Isobutyryloxy)methyl chloride

Chloromethyl 2-methylpropanoate

Chloromethyl 2-methylpropionate

Propanoicacid, 2-methyl-, chloromethyl ester

Chloromethyl isobutyrate

61644-18-6