M35
- Product Name
- M35
- CAS No.
- 142846-71-7
- Chemical Name
- M35
- Synonyms
- M35;GWTLNSAGYLLGPPPGFSPFR-NH2;Galanin receptorligand M35;GALANIN (1-13)-BRADYKININ (2-9) AMIDE;Galanin (1-13)-Bradykinin (2-9), amide, M35;GALANIN FRAGMENT (1-13)-BRADYKININ*FRAGMENT (2-9)AM;GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2;H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2;L-Argininamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-
- CBNumber
- CB3215663
- Molecular Formula
- C107H153N27O26
- Formula Weight
- 2233.52
- MOL File
- 142846-71-7.mol
M35 Property
- storage temp.
- −20°C
- solubility
- Soluble in DMSO
- form
- solid
- color
- White to off-white
- Sequence
- Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-NH2
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- CS-0096574
- Product name
- GalaninReceptorLigandM35
- Purity
- 99.65%
- Packaging
- 1mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- PEP0001396
- Product name
- GALANIN RECEPTOR LIGAND M-35
- Purity
- 95.00%
- Packaging
- 0.5MG
- Price
- $621.39
- Updated
- 2021/12/16
- Product number
- PEP0001396
- Product name
- GALANIN RECEPTOR LIGAND M-35
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $732.5
- Updated
- 2021/12/16
M35 Chemical Properties,Usage,Production
Uses
Galanin Receptor Ligand M35 is a high-affinity ligand and antagonist of galanin receptor (Kd=0.1 nM). Galanin Receptor Ligand M35 exerts a Ki values of 0.11 and 2.0 nM for human galanin receptor type 1 and 2, respectively[1][2].
in vivo
Galanin Receptor Ligand M35 (6 nM/10 μL; i.c.v.) improves the ability of the male Sprague-Dnwley rats to acquire the swim maze task[1].
References
[1] Kask K, et al. Binding and agonist/antagonist actions of M35, galanin(1-13)-bradykinin(2-9)amide chimeric peptide, in Rin m 5F insulinoma cells. Regul Pept. 1995 Nov 10;59(3):341-8. DOI:10.1016/0167-0115(95)00089-t
[2] Webling KE, et al. Galanin receptors and ligands. Front Endocrinol (Lausanne). 2012 Dec 7;3:146. DOI:10.3389/fendo.2012.00146
[3] Ogren SO, et al. Evidence for a role of the neuropeptide galanin in spatial learning. Neuroscience. 1992 Nov;51(1):1-5. DOI:10.1016/0306-4522(92)90463-c
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View Lastest Price from M35 manufacturers
- Product
- M35 142846-71-7
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2020-02-13