3-Bromo-2-methylpyridine
- Product Name
- 3-Bromo-2-methylpyridine
- CAS No.
- 38749-79-0
- Chemical Name
- 3-Bromo-2-methylpyridine
- Synonyms
- 3-BROMO-2-PICOLINE;3-Bromo-2,6-Pyridine DI Corboxilic Acid;3-Bromo-2-methylpyri;2-bromo-4-bromophenol;3-bromo-2-methylpridine;3-bormo-2-methylpyridine;2-METHYL-3-BROMOPYRIDINE;3-BROMO-2-METHYLPYRIDINE;2-Picoline, 3-bromo- (6CI);Pyridine, 3-bromo-2-methyl-
- CBNumber
- CB3235391
- Molecular Formula
- C6H6BrN
- Formula Weight
- 172.02
- MOL File
- 38749-79-0.mol
3-Bromo-2-methylpyridine Property
- Boiling point:
- 76°C/17mm
- Density
- 1.495
- refractive index
- 1.5604
- Flash point:
- 174°F
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 3.59±0.10(Predicted)
- form
- Liquid
- color
- Clear, colorless to brown
- InChI
- InChI=1S/C6H6BrN/c1-5-6(7)3-2-4-8-5/h2-4H,1H3
- InChIKey
- AIPWPTPHMIYYOX-UHFFFAOYSA-N
- SMILES
- C1(C)=NC=CC=C1Br
- CAS DataBase Reference
- 38749-79-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-37/38-41-36/37/38-20/21/22
- Safety Statements
- 26-36/39-36-36/37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 662720
- Product name
- 3-Bromo-2-methylpyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $41.9
- Updated
- 2025/07/31
- Product number
- 662720
- Product name
- 3-Bromo-2-methylpyridine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $30
- Updated
- 2023/06/20
- Product number
- B2962
- Product name
- 3-Bromo-2-methylpyridine
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $40
- Updated
- 2025/07/31
- Product number
- B2962
- Product name
- 3-Bromo-2-methylpyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $122
- Updated
- 2025/07/31
- Product number
- B697578
- Product name
- 3-Bromo-2-methylpyridine
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
3-Bromo-2-methylpyridine Chemical Properties,Usage,Production
Chemical Properties
colorless liquid
Uses
Conversion to the corresponding pyridine carboxaldehyde via peroxide initiated NBS gem-dibromination followed by hydrolysis.
Synthesis
109-06-8
38749-79-0
The general procedure for synthesizing 2-methyl-3-bromopyridine from 2-methylpyridine was as follows: 2-methylpyridine (46.6 g) was slowly added dropwise to aluminum chloride (200 g) with reference to the method of Example 182, and the mixture was stirred continuously at 100°C. Maintaining the same temperature, bromine (40.0 g) was slowly added dropwise to the mixture over a period of 1 hour, followed by continued stirring for 30 minutes. Upon completion of the reaction, the mixture was cooled and poured into ice water, followed by addition of concentrated hydrochloric acid until the mixture was acidified. The resulting solution was washed with ethyl acetate and the aqueous layer was alkalized with 8 mol/L aqueous sodium hydroxide. The alkalized aqueous layer was extracted with ether and the extract was washed with saturated brine and dried with anhydrous sodium sulfate. Subsequently, the extract was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane-ether=10:1) to afford 2-methyl-3-bromopyridine as a colorless oil (yield 5.09 g, 12% yield). The structure of the product was confirmed by 1H-NMR (CDCl3): δ 2.67 (3H, s), 6.98-7.03 (1H, m), 7.78-7.82 (1H, m), 8.40-8.44 (1H, m).
References
[1] Patent: US2007/60623, 2007, A1. Location in patent: Page/Page column 50
3-Bromo-2-methylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
3-Bromo-2-methylpyridine Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28387
- Advantage
- 80
View Lastest Price from 3-Bromo-2-methylpyridine manufacturers
- Product
- 3-Bromo-2-methylpyridine 38749-79-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-30
- Product
- 3-Bromo-2-methylpyridine 38749-79-0
- Price
- US $10.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 50 tons
- Release date
- 2023-09-06
- Product
- 3-Bromo-2-methylpyridine 38749-79-0
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08