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2-CYANOACETANILIDE

Product Name
2-CYANOACETANILIDE
CAS No.
621-03-4
Chemical Name
2-CYANOACETANILIDE
Synonyms
AKOS B029726;Cyanoacetanilide;2-Cyanacetanilid;2-CYANOACETANILIDE;2-Cyanoacetanilide,98%;N-Phenylcyanoacetamide;2-Cyanoacetanilide >O-ACETAMIDOBENZONITRILE;O-ACETAMINOBENZONITRILE;N-Phenyl-2-cyanoacetamide
CBNumber
CB3240036
Molecular Formula
C9H8N2O
Formula Weight
160.17
MOL File
621-03-4.mol
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2-CYANOACETANILIDE Property

Melting point:
198-202 °C
Boiling point:
286.07°C (rough estimate)
Density 
1.1846 (rough estimate)
refractive index 
1.5570 (estimate)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
-1.03±0.10(Predicted)
color 
White to Light yellow
CAS DataBase Reference
621-03-4
EPA Substance Registry System
Acetamide, 2-cyano-N-phenyl- (621-03-4)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
24/25
HS Code 
29269095
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S534161
Product name
2-CYANOACETANILIDE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$185
Updated
2025/07/31
Sigma-Aldrich
Product number
S534161
Product name
2-CYANOACETANILIDE
Purity
Aldrich
Packaging
250mg
Price
$179
Updated
2024/03/01
TCI Chemical
Product number
C2894
Product name
2-Cyanoacetanilide
Purity
>98.0%(GC)
Packaging
1g
Price
$85
Updated
2025/07/31
TCI Chemical
Product number
C2894
Product name
2-Cyanoacetanilide
Purity
>98.0%(GC)
Packaging
5g
Price
$295
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
CHM0008626
Product name
2-CYANOACETANILIDE
Purity
95.00%
Packaging
1G
Price
$694.29
Updated
2021/12/16
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2-CYANOACETANILIDE Chemical Properties,Usage,Production

Chemical Properties

yellowish crystalline powder

Synthesis

62-53-3

105-56-6

621-03-4

A mixture of aniline and ethyl cyanoacetate was added to a 20 mL round-bottom flask followed by [PyPS]3PW12O40 catalyst (140 mg, 0.04 mmol). The reaction mixture was placed in a microwave reactor, heated to the corresponding temperature at 700 W power and stirred. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was diluted with ethyl acetate (20 mL) and stirred continuously for 30 min. The insoluble catalyst was recovered by filtration or centrifugal separation. The filtrate is evaporated and the resulting residue is nearly pure 2-cyanoacetanilide. For further purification, recrystallization or column chromatography may be used.

References

[1] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1985, vol. 21, # 8, p. 998 - 1002
[2] Khimiya Geterotsiklicheskikh Soedinenii, 1985, vol. 21, # 8, p. 1202 - 1206
[3] Tetrahedron Letters, 2015, vol. 56, # 30, p. 4527 - 4531
[4] Synthesis (Germany), 2013, vol. 45, # 1, p. 45 - 52
[5] Pharmazie, 1984, vol. 39, # 1, p. 19 - 21

2-CYANOACETANILIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CYANOACETANILIDE Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
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57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
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Thermo Fisher Scientific
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800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
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China
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17770
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75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
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Shanghai Topbiochem Technology Co., Ltd
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021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
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TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
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View Lastest Price from 2-CYANOACETANILIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Cyano-N-phenylacetamide 621-03-4
Price
US $0.10-10.00/KG
Min. Order
0.10000000149011612KG
Purity
98%
Supply Ability
200TONS
Release date
2025-08-15