Cloquintocet-mexyl
- Product Name
- Cloquintocet-mexyl
- CAS No.
- 99607-70-2
- Chemical Name
- Cloquintocet-mexyl
- Synonyms
- Cloquintocet-1;oquintocet-MexyL;cloquitocet_mexyl;CLOQUINTOCET-MEXYL;Cloquintocet-methyl;Adagrasib Impurity 59;Cloquintocet-mexyl >Cloquintocet-mexyl Standard;Cloquintocet-mexyl in Acetone;Cloquintocet-mexyl in Methanol
- CBNumber
- CB3243431
- Molecular Formula
- C18H22ClNO3
- Formula Weight
- 335.83
- MOL File
- 99607-70-2.mol
Cloquintocet-mexyl Property
- Melting point:
- 69°
- Boiling point:
- 448.4±30.0 °C(Predicted)
- Density
- 1.163±0.06 g/cm3(Predicted)
- vapor pressure
- 0-54.4Pa at 25-185.9℃
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
- form
- Solid
- pka
- 1.94±0.29(Predicted)
- color
- White to Off-White
- Merck
- 14,2401
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- LogP
- 5.2-5.24 at 25℃ and pH5-9.1
- Surface tension
- 56.8-57.2mN/m at 590μg/L and 20℃
- Dissociation constant
- 3.55 at 20℃
- CAS DataBase Reference
- 99607-70-2(CAS DataBase Reference)
- EPA Substance Registry System
- Cloquintocet-mexyl (99607-70-2)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 31678
- Product name
- Cloquintocet-mexyl
- Purity
- PESTANAL
- Packaging
- 250mg
- Price
- $91.1
- Updated
- 2024/03/01
- Product number
- C2682
- Product name
- Cloquintocet-mexyl
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $48
- Updated
- 2024/03/01
- Product number
- C583525
- Product name
- Cloquintocet-mexyl
- Packaging
- 2.5g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- 171095
- Product name
- 1-Methylhexyl 2-[(5-chloro-8-quinolinyl)oxy]acetate
- Packaging
- 1g
- Price
- $148
- Updated
- 2021/12/16
- Product number
- 39361
- Product name
- Cloquintocet-mexyl,≥98%(Assaybytitration,HPLC)
- Purity
- ≥98%(Assaybytitration,HPLC)
- Packaging
- 1G
- Price
- $154.92
- Updated
- 2021/12/16
Cloquintocet-mexyl Chemical Properties,Usage,Production
Description
Cloquintocet-mexyl is a colourless crystalline herbicide safener. It is categorized as Class III toxin.
Chemical Properties
beige solid
Uses
Cloquintocet-mexyl is used as a herbicide.
Uses
Cloquintocet-mexyl is a herbicide. It is used to control coarse annual grass of the family poaceae (gramineae). lt was developed by the swiss ciba geigy in the 1980s and the patent has expired.
Definition
ChEBI: Heptan-2-yl [(5-chloroquinolin-8-yl)oxy]acetate is a member of the class of quinolines that is quinoline which is substituted by a chloro group at position 5 and by a 2-[(heptan-2-yl)oxy]-2-oxoethoxy group at position 8. It is an aromatic ether, an organochlorine compound, a member of quinolines and a carboxylic ester.
Agricultural Uses
Cloquintocet-mexyl is a safener that can be used in conjunction with various herbicides to reduce phytotoxicity to crops. Though effective as a safener, the manufacture, storage, and use of cloquintocet-mexyl containing products can present challenges owing to its sensitivity to water and its low melting temperature (i.e., 61-69° C. for technical material). When products containing cloquintocet-mexyl are prepared, stored, or used in the presence of water, cloquin tocet-mexyl can undergo hydrolysis to form cloquintocet acid, and/or form a needle-shaped, crystalline hydrate that can, lead to clogged spray nozzles during spray applications and/or possibly increased levels of crop phytotoxicity.
Carcinogenicity
In accordance with the EPA Proposed EPA Weight-of-the-Evidence Categories, August 1999, the HIARC classified cloquintocet-mexyl as "not likely to be a human carcinogen." Carcinogenicity studies in rats and mice did not show increased incidence of spontaneous tumor formation. With negative mutagenic test battery, it is suggested that cloquintocet-mexyl (CGA 185072) is not likely to be a human carcinogen.
Metabolism
Metabolism studies in rats indicated that approximately 40% of the administered dose of cloquintocet-mexyl was absorbed through the gastrointestinal tract and subsequently excreted via the urine. Fecal excretion accounted for approximately 60% of the administered dose. The chemical was rapidly eliminated (more than 80% of the administered dose) via feces and urine within 48 hours post-dosing. Sex, dosing regime, and dose levels had little effect on the excretion pattern. Excretion patterns were similar between the biliary cannulated and non-cannulated animals indicating that there was no enterohepatic circulation of the chemical. Three days after administration, tissue radioactivity accounted for less than 0.3% of the administered dose (or was non-detectable) and was not detectable in the expired air. At day three post-dosing, most tissue residues of radioactivity were below the limit of detection. The major metabolic pathway of cloquintocet-mexyl was ester hydrolysis to yield 5-chloro-8-quinolinoxy acetic acid, the major metabolite in the fecal and urinary pools.
Toxicity evaluation
Cloquintocet-mexyl has a low order of acute oral, dermal, and inhalation toxicity. It is slightly irritating to the eyes and non-irritating to the skin. Cloquintocet-mexyl is a skin sensitizer. The chemical is not genotoxic and is not a reproductive and developmental toxicant. There is no evidence of neurotoxicity in the available studies. Cloquintocet-mexyl is classified as “not likely to be a human carcinogen.” The main metabolite for cloquintocet-mexyl is 5-chloro-8-quin-linoxyacetic acid, and testing on the metabolite is part of the toxicology database for cloquintocet-mexyl.
Cloquintocet-mexyl Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Cloquintocet-mexyl manufacturers
- Product
- Cloquintocet-mexyl 99607-70-2
- Price
- US $30.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-03-26
- Product
- cloquintocet-mexyl 99607-70-2
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-09-05
- Product
- Cloquintocet-mexyl 99607-70-2
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-24