3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE
Physical Form- Product Name
- 3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE
- CAS No.
- 143591-61-1
- Chemical Name
- 3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE
- Synonyms
- 8-Chloro-3-bromoimidazo[1,2-a]pyrazine;3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE;Imidazo[1,2-a]pyrazine, 3-bromo-8-chloro-
- CBNumber
- CB32452778
- Molecular Formula
- C6H3BrClN3
- Formula Weight
- 232.47
- MOL File
- 143591-61-1.mol
3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE Property
- Density
- 2.03±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -1.45±0.30(Predicted)
- Appearance
- Off-white to light brown Solid
- InChI
- InChI=1S/C6H3BrClN3/c7-4-3-10-6-5(8)9-1-2-11(4)6/h1-3H
- InChIKey
- MCEGPQSPRNOFMG-UHFFFAOYSA-N
- SMILES
- C12=NC=C(Br)N1C=CN=C2Cl
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- FB134017
- Product name
- 3-Bromo-8-chloroimidazo[1,2-a]pyrazine
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FB134017
- Product name
- 3-Bromo-8-chloroimidazo[1,2-a]pyrazine
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 072298
- Product name
- 3-Bromo-8-chloroimidazo[1,2-a]pyrazine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $131
- Updated
- 2021/12/16
- Product number
- 3H32-D-38
- Product name
- 3-Bromo-8-chloroimidazo[1,2-a]pyrazine
- Packaging
- 1g
- Price
- $149
- Updated
- 2021/12/16
- Product number
- FB134017
- Product name
- 3-Bromo-8-chloroimidazo[1,2-a]pyrazine
- Packaging
- 5G
- Price
- $250
- Updated
- 2021/12/16
3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE Chemical Properties,Usage,Production
Physical Form
Solid
Synthesis
69214-33-1
143591-61-1
General procedure for the synthesis of 3-bromo-8-chloroimidazo[1,2-a]pyrazine from 8-chloroimidazo[1,2-a]pyrazine: N-bromosuccinimide (1.78 g, 10 mmol) was added to a solution of 8-chloroimidazo[1,2-a]pyrazine (1.53 g, 10 mmol) in dichloromethane (30 mL), and the reaction was stirred for 2 hours at room temperature. After the reaction was completed, the reaction mixture was washed with saturated aqueous sodium carbonate solution (2×20 mL), dried with anhydrous magnesium sulfate, filtered, and the filtrate was concentrated under reduced pressure to give 3-bromo-8-chloroimidazo[1,2-a]pyrazine (2.11 g, 96% yield).
References
[1] Patent: WO2009/24585, 2009, A2. Location in patent: Page/Page column 46
[2] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 6, p. 1582 - 1585
[3] European Journal of Medicinal Chemistry, 2016, vol. 108, p. 623 - 643
[4] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 17, p. 5170 - 5174
[5] Patent: WO2012/80229, 2012, A1. Location in patent: Page/Page column 40
3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE manufacturers
- Product
- 3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE 143591-61-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-08