ChemicalBook > CAS DataBase List > 3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE

3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE

Physical Form

Product Name: 3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE
CAS No.: 143591-61-1
Chemical Name: 3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE
Synonyms: 8-Chloro-3-bromoimidazo[1,2-a]pyrazine;3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE;Imidazo[1,2-a]pyrazine, 3-bromo-8-chloro-
CBNumber: CB32452778
Molecular Formula: C6H3BrClN3
Formula Weight: 232.47
MOL File: 143591-61-1.mol

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3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE Property

Density: 2.03±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -1.45±0.30(Predicted)
Appearance: Off-white to light brown Solid
InChI: InChI=1S/C6H3BrClN3/c7-4-3-10-6-5(8)9-1-2-11(4)6/h1-3H
InChIKey: MCEGPQSPRNOFMG-UHFFFAOYSA-N
SMILES: C12=NC=C(Br)N1C=CN=C2Cl

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FB134017
Product name: 3-Bromo-8-chloroimidazo[1,2-a]pyrazine
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB134017
Product name: 3-Bromo-8-chloroimidazo[1,2-a]pyrazine
Packaging: 1g
Price: $100
Updated: 2021/12/16

Matrix Scientific

Product number: 072298
Product name: 3-Bromo-8-chloroimidazo[1,2-a]pyrazine
Purity: 95+%
Packaging: 1g
Price: $131
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-D-38
Product name: 3-Bromo-8-chloroimidazo[1,2-a]pyrazine
Packaging: 1g
Price: $149
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB134017
Product name: 3-Bromo-8-chloroimidazo[1,2-a]pyrazine
Packaging: 5G
Price: $250
Updated: 2021/12/16

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3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE Chemical Properties,Usage,Production

Physical Form

Solid

Synthesis

69214-33-1

143591-61-1

General procedure for the synthesis of 3-bromo-8-chloroimidazo[1,2-a]pyrazine from 8-chloroimidazo[1,2-a]pyrazine: N-bromosuccinimide (1.78 g, 10 mmol) was added to a solution of 8-chloroimidazo[1,2-a]pyrazine (1.53 g, 10 mmol) in dichloromethane (30 mL), and the reaction was stirred for 2 hours at room temperature. After the reaction was completed, the reaction mixture was washed with saturated aqueous sodium carbonate solution (2×20 mL), dried with anhydrous magnesium sulfate, filtered, and the filtrate was concentrated under reduced pressure to give 3-bromo-8-chloroimidazo[1,2-a]pyrazine (2.11 g, 96% yield).

References

[1] Patent: WO2009/24585, 2009, A2. Location in patent: Page/Page column 46
[2] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 6, p. 1582 - 1585
[3] European Journal of Medicinal Chemistry, 2016, vol. 108, p. 623 - 643
[4] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 17, p. 5170 - 5174
[5] Patent: WO2012/80229, 2012, A1. Location in patent: Page/Page column 40

3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE manufacturers

Career Henan Chemical Co

Product: 3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE 143591-61-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-08

143591-61-1, 3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINERelated Search:

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3-BROMO-8-CHLOROIMIDAZO[1,2-A]PYRAZINE

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143591-61-1