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1-BROMO-3-CHLORO-5-METHOXYBENZENE

Product Name
1-BROMO-3-CHLORO-5-METHOXYBENZENE
CAS No.
174913-12-3
Chemical Name
1-BROMO-3-CHLORO-5-METHOXYBENZENE
Synonyms
3-Bromo-5-chloroanisole;Phloroglucinol Impurity 56;Phloroglucinol Impurity 34;1-BROMO-3-CHLORO-5-METHOXYBENZENE;Benzene, 1-bromo-3-chloro-5-methoxy-;3-bromo-5-chlorotrifluoromethoxybenzene;1-BROMO-3-CHLORO-5-METHOXYBENZENE ISO 9001：2015 REACH
CBNumber
CB32455168
Molecular Formula
C7H6BrClO
Formula Weight
221.48
MOL File
174913-12-3.mol
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1-BROMO-3-CHLORO-5-METHOXYBENZENE Property

Boiling point:
236.5±20.0 °C(Predicted)
Density 
1.564±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
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Safety

HS Code 
2909303890
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B683568
Product name
3-Bromo-5-chloroanisole
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
B683568
Product name
3-Bromo-5-chloroanisole
Packaging
500mg
Price
$55
Updated
2021/12/16
AK Scientific
Product number
W3821
Product name
1-Bromo-3-chloro-5-methoxybenzene
Packaging
25g
Price
$237
Updated
2021/12/16
Apolloscientific
Product number
OR400559
Product name
3-Bromo-5-chloroanisole
Packaging
25g
Price
$269
Updated
2021/12/16
Matrix Scientific
Product number
076555
Product name
1-Bromo-3-chloro-5-methoxybenzene
Purity
95+%
Packaging
25g
Price
$149
Updated
2021/12/16
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1-BROMO-3-CHLORO-5-METHOXYBENZENE Chemical Properties,Usage,Production

Uses

1-Bromo-3-chloro-5-methoxybenzene is a commonly used organobenzene compound whose bromine or chlorine atoms on the benzene ring structure can be replaced by other halogenated atoms for the synthesis of other halogenated methoxybenzene derivatives. It can also be used to synthesise 3-Bromo-5-chlorophenol and its derivatives.

Synthesis

1-Bromo-3-chloro-5-methoxybenzene is prepared by the reaction of 1-bromo-3-chloro-5-fluoro-benzene and Sodium methanolate. The specific synthesis steps are as follows:
A solution of 1-bromo-3-chloro-5-fluoro-benzene (42a, 55 g, 263 mmol) was cooled to 0° C. and treated with a 25percent methanolic sodium methoxide solution (68 mL, 315 mmol) and heated to 40° C. for 3 h. The solution was cooled and partitioned between water (1 L) and a 1:1 mixture of hexane/diethyl ether (3.x.200 mL). The combined extracts were washed with brine (60 mL), dried (Na2SO4), filtered and the solvents evaporated in vacuo to afford 42b as an oil (57.3 g, 92percent pure, 238 mmol). The ether 42b (43 g, 173 mmol) was treated with glacial HOAc (150 mL) and 48percent aqueous HBr (100 mL) and heated to 120° C. After 40 h, the volatiles were removed while heated to 80° C. and then cooled to RT. The residue was partitioned between water (100 mL) and DCM (3.x.250 mL). The combined extracts were washed with H2O (50 mL), aqueous NaHCO3solution (2.x.50 mL), brine (50 mL), and (MgSO4). The solvents were removed to afford 23.3 g of 1-Bromo-3-chloro-5-methoxybenzene as a grey solid.

1-BROMO-3-CHLORO-5-METHOXYBENZENE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BROMO-3-CHLORO-5-METHOXYBENZENE Suppliers

China 119 Germany 1 India 2 United Kingdom 2 United States 8 Global 132
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from 1-BROMO-3-CHLORO-5-METHOXYBENZENE manufacturers

Henan Fengda Chemical Co., Ltd
Product
1-Bromo-3-chloro-5-methoxybenzene 174913-12-3
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30
Career Henan Chemical Co
Product
1-BROMO-3-CHLORO-5-METHOXYBENZENE 174913-12-3
Price
US $2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-24

174913-12-3, 1-BROMO-3-CHLORO-5-METHOXYBENZENERelated Search:

2-Bromo-4-chloro-6-fluorotoluene 3-Bromo-2-iodotoluene 2-BROMO-4-METHYLBENZOTRIFLUORIDE 3-fluoro-5-iodobenzodifluoride 1-BROMO-2,3-DIFLUORO-5-METHYLBENZENE 2-BROMO-4-CHLORO-6-NITROTOLUENE 2-bromo-6-chloro-3-fluorotoluene 2,6-Dichloro-4-fluorobenzotrifluoride 2-Chloro-3-fluorobenzotrifluoride 2,6-Dibromobenzotrifluoride 2-CHLORO-4-FLUOROBENZOTRIFLUORIDE 2,4-Dibromo-6-fluorotoluene 3-Bromo-5-chlorophenol 2-Chloro-4-bromo-6-trifluoromethoxyaniline 4-bromo-6-chlorobenzo[d]oxazol-2(3H)-one 1-BROMO-3-CHLORO-5-METHOXYBENZENE

  • 1-BROMO-3-CHLORO-5-METHOXYBENZENE
  • 3-Bromo-5-chloroanisole
  • Benzene, 1-bromo-3-chloro-5-methoxy-
  • Phloroglucinol Impurity 34
  • 3-bromo-5-chlorotrifluoromethoxybenzene
  • 1-BROMO-3-CHLORO-5-METHOXYBENZENE ISO 9001：2015 REACH
  • Phloroglucinol Impurity 56
  • 174913-12-3