Treprostinil Sodium
- Product Name
- Treprostinil Sodium
- CAS No.
- 289480-64-4
- Chemical Name
- Treprostinil Sodium
- Synonyms
- Troprostil sodium;UT 15 (pharMaceutical);Treprostinil Sodium API;Treprostinil sodium salt;Treprostinil Sodium (UT-15);Treprostinil sodium (LRX15);289480-64-4 Treprostinil Sodium;Prostaglandin Receptor,UT15,Treprostinil Sodium,inhibit,Treprostinil,UT 15,Inhibitor;2-(((1R,2R,3aS,9aS)-2-Hydroxy-1-((S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl)oxy)acetic acid, sodium salt;Treprostinil 13C2 D1 Sodium SaltQ: What is Treprostinil 13C2 D1 Sodium Salt Q: What is the CAS Number of Treprostinil 13C2 D1 Sodium Salt Q: What is the storage condition of Treprostinil 13C2 D1 Sodium Salt Q: What are the applications of Treprostinil 13C2 D1 Sodium Salt
- CBNumber
- CB32460050
- Molecular Formula
- C23H35NaO5
- Formula Weight
- 414.52
- MOL File
- 289480-64-4.mol
Treprostinil Sodium Property
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMSO : ≥ 26 mg/mL (63.03 mM)
- form
- solid
- color
- White
- InChIKey
- XUACDQZEUSYNGG-DJYDVLTONA-N
- SMILES
- C([C@H]1[C@@H](C[C@]2([H])CC3=C(C=CC=C3C[C@]12[H])OCC(=O)O)O)C[C@@H](O)CCCCC.[NaH] |&1:1,2,4,14,23,r|
Safety
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-6170
- Product name
- Treprostinilsodium
- Purity
- >98.0%
- Packaging
- 1mg
- Price
- $84
- Updated
- 2021/12/16
- Product number
- BISN0021
- Product name
- TreprostinilSodium
- Purity
- 97%
- Packaging
- 1mg
- Price
- $116
- Updated
- 2021/12/16
- Product number
- Y0243
- Product name
- Treprostinilsodium
- Packaging
- 5mg
- Price
- $196
- Updated
- 2021/12/16
- Product number
- CS-6170
- Product name
- Treprostinilsodium
- Purity
- >98.0%
- Packaging
- 5mg
- Price
- $264
- Updated
- 2021/12/16
- Product number
- BISN0021
- Product name
- TreprostinilSodium
- Purity
- 97%
- Packaging
- 5mg
- Price
- $319
- Updated
- 2021/12/16
Treprostinil Sodium Chemical Properties,Usage,Production
Description
Treprostinil sodium is a chemically stable prostacyclin analogue that shares at least some of the pharmacologic actions of epoprostenol. The sodium salt of treprostinil is currently approved for the treatment of PAH for either parenteral (Remodulin) or inhaled (Tyvaso) routes of administration. Acute hemodynamic effects with treprostinil are similar to those observed with intravenous epoprostenol in patients with IPAH; however, treprostinil is stable at room temperature and neutral pH and has a longer half-life, 2–3 hours, when administered subcutaneously. Like epoprostenol, treprostinil is infused continuously by a portable pump and can be administered subcutaneously or intravenously. Treprostinil was approved in 2002 for subcutaneous infusion and in 2004 for intravenous injection[1].
Uses
Treprostinil sodium is a potent agonist of DP1, EP2 and IP receptors with Ki 4.4 nM, 3.6 nM and 32 nM, respectively.
Definition
ChEBI: Treprostinil sodium is an organic sodium salt. It contains a treprostinil.
References
[1] Zhi-Cheng Jing. “Efficacy and safety of oral treprostinil monotherapy for the treatment of pulmonary arterial hypertension: a randomized, controlled trial.” Circulation 127 5 (2013): 624–33.
Treprostinil Sodium Preparation Products And Raw materials
Raw materials
Preparation Products
Treprostinil Sodium Suppliers
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View Lastest Price from Treprostinil Sodium manufacturers
- Product
- treprostinil sodium 289480-64-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-26
- Product
- REMODULIN 289480-64-4
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-02