8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
Uses- Product Name
- 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
- CAS No.
- 1124382-72-4
- Chemical Name
- 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
- Synonyms
- 8-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine;106347;EOS-61162;2-AMino-8-broMo[1,2,4]triazolo[1,5-a]pyridine;8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine;[1,2,4]Triazolo[1,5-a]pyridin-2-amine, 8-bromo-;8-bromo - [1,2,4] thiazolo [1,5-a] pyridine-2-amine;8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- CBNumber
- CB32500152
- Molecular Formula
- C6H5BrN4
- Formula Weight
- 213.03
- MOL File
- 1124382-72-4.mol
8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Property
- Density
- 2.09
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- solid
- pka
- 3.83±0.30(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C6H5BrN4/c7-4-2-1-3-11-5(4)9-6(8)10-11/h1-3H,(H2,8,10)
- InChIKey
- SUFKKFLJJMKVJJ-UHFFFAOYSA-N
- SMILES
- C12=NC(N)=NN1C=CC=C2Br
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- SYX00251
- Product name
- 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $216
- Updated
- 2025/07/31
- Product number
- B415610
- Product name
- 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-W008562
- Product name
- 2-Amino-8-bromo[1,2,4]triazolo[1,5-a]pyridine
- Purity
- ≥97.0%
- Packaging
- 1g
- Price
- $64
- Updated
- 2021/12/16
- Product number
- 2183AA
- Product name
- 2-Amino-8-bromo[1,2,4]triazolo[1,5-a]pyridine
- Packaging
- 250mg
- Price
- $109
- Updated
- 2021/12/16
- Product number
- 3H32-9-6P
- Product name
- 2-Amino-8-bromo-[1,2,4]triazolo[1,5-a]pyridine
- Packaging
- 250mg
- Price
- $149
- Updated
- 2021/12/16
8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Chemical Properties,Usage,Production
Uses
8-Bromo-[1,2,4]thiazo[1,5-a]pyridine-2-amine is a pyridine derivative that can be used as a pharmaceutical synthesis intermediate for pharmaceutical synthesis and experimental research.
Synthesis
1124383-00-1
1124382-72-4
The general procedure for the synthesis of 2-amino-8-bromo[1,2,4]triazolo[1,5-a]pyridine from compound (CAS:1124383-00-1) is as follows: 1. Dissolution step: Methanol (MeOH, 300 mL), hydroxylamine hydrochloride (62.83 g, 904 mmol) and diisopropylethylamine (DIPEA, 694 mL, 543 mmol) were added to a solution of Intermediate 50 (55 g, 181 mmol) in ethanol (EtOH, 300 mL). 2. Reaction step: the reaction mixture was stirred at room temperature (r.t.) for 6 hours. 3. Post-treatment step: the reaction mixture was concentrated in vacuum and the residue was suspended in diisopropyl ether (DIPE). 4. Separation step: the precipitate was collected by filtration. 5. 5. Yield: 51 37 g of intermediate were obtained in 96% yield.
References
[1] Patent: WO2013/10904, 2013, A1. Location in patent: Page/Page column 76
[2] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 17, p. 4794 - 4800
[3] Patent: KR2015/77599, 2015, A. Location in patent: Paragraph 0096; 0099-0101
[4] Patent: KR101601354, 2016, B1. Location in patent: Paragraph 0110 - 0112
[5] Patent: US2011/190269, 2011, A1. Location in patent: Page/Page column 66
8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Preparation Products And Raw materials
Raw materials
Preparation Products
8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Suppliers
- Tel
- 010-57903446 15869909019
- Fax
- 010-57903446
- 168931144@qq.com
- Country
- China
- ProdList
- 2875
- Advantage
- 58
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 15883
- Advantage
- 64
- Tel
- 025-52161033 15312098939
- Fax
- 025-83254025
- sales@njdrschem.com
- Country
- China
- ProdList
- 583
- Advantage
- 64
- Tel
- 029-86538357
- Fax
- 029-87871708
- Country
- China
- ProdList
- 234
- Advantage
- 57
- Tel
- 18986259541
- Fax
- 027-87840182
- sales@3stc.com
- Country
- China
- ProdList
- 3763
- Advantage
- 58
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9510
- Advantage
- 58
- Tel
- 18652989687
- Fax
- +86-25-52131256
- sales@norris-pharm.com
- Country
- China
- ProdList
- 8878
- Advantage
- 55
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9342
- Advantage
- 55
View Lastest Price from 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine manufacturers
- Product
- 8-Bromo[1,2,4]triazolo[1,5-a]pyridin-2-amine 1124382-72-4
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-09