8-BROMO-2-METHOXY-1,5-NAPHTHYRIDINE
- Product Name
- 8-BROMO-2-METHOXY-1,5-NAPHTHYRIDINE
- CAS No.
- 881658-92-0
- Chemical Name
- 8-BROMO-2-METHOXY-1,5-NAPHTHYRIDINE
- Synonyms
- 8-BROMO-2-METHOXY-1,5-NAPHTHYRIDINE;8-Bromo-2-methyloxy-1,5-naphthyridine;1,5-Naphthyridine, 8-broMo-2-Methoxy-
- CBNumber
- CB7837812
- Molecular Formula
- C9H7BrN2O
- Formula Weight
- 239.07
- MOL File
- 881658-92-0.mol
8-BROMO-2-METHOXY-1,5-NAPHTHYRIDINE Property
- Boiling point:
- 324.8±37.0 °C(Predicted)
- Density
- 1.591±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 1.39±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2914390090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P322Specific measures (see …on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 1545AF
- Product name
- 8-Bromo-2-methoxy-1,5-naphthyridine
- Packaging
- 250mg
- Price
- $194
- Updated
- 2021/12/16
- Product number
- 1545AF
- Product name
- 8-Bromo-2-methoxy-1,5-naphthyridine
- Packaging
- 1g
- Price
- $412
- Updated
- 2021/12/16
- Product number
- HCH0352615
- Product name
- 8-BROMO-2-METHOXY-1,5-NAPHTHYRIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.98
- Updated
- 2021/12/16
- Product number
- 087224
- Product name
- 8-Bromo-2-methoxy-1,5-naphthyridine
- Purity
- >95%
- Packaging
- 500mg
- Price
- $908
- Updated
- 2021/12/16
- Product number
- CD11035656
- Product name
- 8-Bromo-2-methoxy-1,5-naphthyridine
- Purity
- 95%
- Packaging
- 5g
- Price
- $732
- Updated
- 2021/12/16
8-BROMO-2-METHOXY-1,5-NAPHTHYRIDINE Chemical Properties,Usage,Production
Synthesis
23443-25-6
881658-92-0
6-Methoxy-1,5-naphthyridin-4-ol (21.5 g) was dissolved in DMF (150 mL) under nitrogen protection and stirred at 0 °C. Phosphorus tribromide (13.5 mL) was slowly added dropwise, and after the dropwise addition was completed, the reaction mixture was gradually warmed up to room temperature, and the reaction was continued to be stirred for 90 min. Upon completion of the reaction, the reaction was quenched by the addition of water (375 mL) and the pH was adjusted with solid sodium carbonate to 7. The precipitated solid product was collected by diafiltration and dried by suction with a sintered funnel for 2 h, followed by drying under vacuum at 45 °C to afford the target compound 8-bromo-2-methoxy-1,5-naphthyridine (26.0 g, 90% yield). The product was characterized by 1H-NMR (DMSO-d6) with the following chemical shifts (δ, ppm): 8.59 (d, 1H), 8.30 (d, 1H), 8.08 (d, 1H), 7.33 (d, 1H), 4.06 (s, 3H).
References
[1] Patent: EP2080761, 2009, A1. Location in patent: Page/Page column 15
[2] Patent: WO2010/81874, 2010, A1. Location in patent: Page/Page column 17-18
[3] Patent: US2006/223810, 2006, A1. Location in patent: Page/Page column 18
[4] Patent: WO2010/101949, 2010, A1. Location in patent: Page/Page column 125
8-BROMO-2-METHOXY-1,5-NAPHTHYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 8-BROMO-2-METHOXY-1,5-NAPHTHYRIDINE manufacturers
- Product
- 8-BROMO-2-METHOXY-1,5-NAPHTHYRIDINE 881658-92-0
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-13