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Amifostine Thiol Dihydrochloride

Product Name
Amifostine Thiol Dihydrochloride
CAS No.
14653-77-1
Chemical Name
Amifostine Thiol Dihydrochloride
Synonyms
SKL052;WR-1065 2HCl;AMifostine Thiol;WR-1065 dihydrochloride;Amifostine Impurity 1 DiHCl;Amifostine Impurity 10 DiHCl;Amifostine Thiol Dihydrochloride;Amifostine thiol (hydrochloride);Amifostine Thiol Dihydrochloride (90%);Amifostine Impurity 2(Amifostine Thiol)
CBNumber
CB32502994
Molecular Formula
C5H14N2S
Formula Weight
134.24306
MOL File
14653-77-1.mol
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Amifostine Thiol Dihydrochloride Property

Melting point:
184-186°C
storage temp. 
-20°C
solubility 
H2O: ≥20mg/mL
form 
powder
color 
white to off-white
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xn
Risk Statements 
22-41
Safety Statements 
26-39-41
WGK Germany 
3
HS Code 
2930909165
Toxicity
mouse,LD50,intraperitoneal,400mg/kg (400mg/kg),European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 24, Pg. 48, 1989.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W2020
Product name
WR-1065
Purity
≥98% (HPLC)
Packaging
10mg
Price
$100
Updated
2024/03/01
Sigma-Aldrich
Product number
1019428
Product name
Amifostine thiol
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$1210
Updated
2024/03/01
Cayman Chemical
Product number
18612
Product name
Amifostine thiol (hydrochloride)
Packaging
5mg
Price
$45
Updated
2024/03/01
Cayman Chemical
Product number
18612
Product name
Amifostine thiol (hydrochloride)
Packaging
10mg
Price
$81
Updated
2024/03/01
Sigma-Aldrich
Product number
W2020
Product name
WR-1065
Purity
≥98% (HPLC)
Packaging
50mg
Price
$407
Updated
2024/03/01
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Amifostine Thiol Dihydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A metabolite of Amifostine.

Biochem/physiol Actions

WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.

storage

Desiccate at -20°C

Amifostine Thiol Dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Amifostine Thiol Dihydrochloride Suppliers

Huayin Sample Biological Technology Co. LTD
Tel
13892502238
Email
1453186328@qq.com
Country
China
ProdList
494
Advantage
58
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd.
Tel
027-65388397 18164111589
Fax
027-65388397
Email
3321478047@qq.com
Country
China
ProdList
1998
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Shenzhen Pharma Technology Co., Ltd.
Tel
0755-86648230
Fax
0755-86648231
Email
pharma08@sina.com
Country
China
ProdList
166
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq:2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9347
Advantage
55
Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58

14653-77-1, Amifostine Thiol DihydrochlorideRelated Search:


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  • 14653-77-1
  • C5H16Cl2N2S
  • C5H14N2S2HCl
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