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Amifostine Thiol Dihydrochloride

Product Name
Amifostine Thiol Dihydrochloride
CAS No.
14653-77-1
Chemical Name
Amifostine Thiol Dihydrochloride
Synonyms
SKL052;WR-1065 2HCl;AMifostine Thiol;WR-1065 dihydrochloride;Amifostine Impurity 1 DiHCl;Amifostine Impurity 10 DiHCl;Amifostine Thiol Dihydrochloride;Amifostine thiol (hydrochloride);Amifostine Thiol Dihydrochloride (90%);Amifostine Impurity 2（Amifostine Thiol）
CBNumber
CB32502994
Molecular Formula
C5H14N2S
Formula Weight
134.24306
MOL File
14653-77-1.mol
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Amifostine Thiol Dihydrochloride Property

Melting point:
184-186°C
storage temp. 
-20°C
solubility 
H2O: ≥20mg/mL
form 
powder
color 
white to off-white
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xn
Risk Statements 
22-41
Safety Statements 
26-39-41
WGK Germany 
3
HS Code 
2930909165
Toxicity
mouse,LD50,intraperitoneal,400mg/kg (400mg/kg),European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 24, Pg. 48, 1989.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W2020
Product name
WR-1065
Purity
≥98% (HPLC)
Packaging
10mg
Price
$100
Updated
2024/03/01
Sigma-Aldrich
Product number
1019428
Product name
Amifostine thiol
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$1210
Updated
2024/03/01
Cayman Chemical
Product number
18612
Product name
Amifostine thiol (hydrochloride)
Packaging
5mg
Price
$45
Updated
2024/03/01
Cayman Chemical
Product number
18612
Product name
Amifostine thiol (hydrochloride)
Packaging
10mg
Price
$81
Updated
2024/03/01
Sigma-Aldrich
Product number
W2020
Product name
WR-1065
Purity
≥98% (HPLC)
Packaging
50mg
Price
$407
Updated
2024/03/01
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Amifostine Thiol Dihydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A metabolite of Amifostine.

Biochem/physiol Actions

WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.

storage

Desiccate at -20°C

Amifostine Thiol Dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Amifostine Thiol Dihydrochloride Suppliers

Canada 1 China 74 India 4 United Kingdom 3 United States 9 USA 1 Global 92
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
Whyte Chemicals
Tel
--
Fax
--
Email
sales@whytechemicals.co.uk
Country
United Kingdom
ProdList
3748
Advantage
50

14653-77-1, Amifostine Thiol DihydrochlorideRelated Search:

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  • Amifostine Thiol (50 mg) (Ethanethiol, 2-[(3-aminopropyl)amino]-, dihydrochloride)
  • 14653-77-1
  • C5H16Cl2N2S
  • C5H14N2S2HCl
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Sulfur & Selenium Compounds