5-Amino-1,2,4-thiadiazole
Physical Form- Product Name
- 5-Amino-1,2,4-thiadiazole
- CAS No.
- 7552-07-0
- Chemical Name
- 5-Amino-1,2,4-thiadiazole
- Synonyms
- 5,10-DIHYDROINDOLO...;1,2,4-THIADIAZOL-5-AMINE;1,2,4-Thiadiazole-5-aMine;5-AMINO-1,2,4-THIADIAZOLE;1,2,4-THIADIAZOL-5-YLAMINE;1,2,4-Thiadiazole, 5-amino-;1,2,4-Thiadiazol-5-amine(9CI);5-AMino-1,2,4-thiadiazole HCl;[1,2,4]Thiadiazol-5-ylaMine.HCl;1,2,4-Thiadiazol-5-amine (9CI, ACI)
- CBNumber
- CB3250680
- Molecular Formula
- C2H3N3S
- Formula Weight
- 101.13
- MOL File
- 7552-07-0.mol
5-Amino-1,2,4-thiadiazole Property
- Melting point:
- 112-115°C
- Boiling point:
- 238.9±23.0 °C(Predicted)
- Density
- 1.495±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- solid
- pka
- 3.97±0.50(Predicted)
- color
- Yellow
- InChI
- InChI=1S/C2H3N3S/c3-2-4-1-5-6-2/h1H,(H2,3,4,5)
- InChIKey
- VJHTZTZXOKVQRN-UHFFFAOYSA-N
- SMILES
- S1C(N)=NC=N1
- CAS DataBase Reference
- 7552-07-0(CAS DataBase Reference)
- NIST Chemistry Reference
- 5-Amino-1,2,4-thiadiazole(7552-07-0)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
N-Bromosuccinimide Price
- Product number
- A633308
- Product name
- 5-Amino-1,2,4-thiadiazole
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- CS-0037734
- Product name
- 1,2,4-Thiadiazol-5-amine
- Purity
- >97.0%
- Packaging
- 1g
- Price
- $26
- Updated
- 2021/12/16
- Product number
- 027101
- Product name
- 1,2,4-Thiadiazol-5-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $58
- Updated
- 2021/12/16
- Product number
- CS-0037734
- Product name
- 1,2,4-Thiadiazol-5-amine
- Purity
- >97.0%
- Packaging
- 5g
- Price
- $83
- Updated
- 2021/12/16
- Product number
- V2374
- Product name
- 5-Amino-1,2,4-thiadiazole
- Packaging
- 1g
- Price
- $90
- Updated
- 2021/12/16
5-Amino-1,2,4-thiadiazole Chemical Properties,Usage,Production
Physical Form
Solid
Uses
5-Amino-1,2,4-thiadiazole is a useful research chemical for organic synthesis and other chemical processes.
Synthesis
943653-32-5
7552-07-0
The general procedure for the synthesis of 5-amino-1,2,4-thiadiazole from the compound (CAS: 943653-32-5) is as follows: (E)-N'-carbamoyl-N,N-dimethylformamide (3.9 g, 30 mmol), hydroxylamine-O-sulphonic acid (3.7 g, 33 mmol) were mixed with anhydrous ethanol (100 mL) and reacted by heating at 80 °C for for 8 hours. Upon completion of the reaction, the mixture was cooled to room temperature, triethylamine was added and stirring was continued at room temperature for 19 hours. Subsequently, the solvent was removed by distillation under reduced pressure, and the residue was dissolved in a mixture of dichloromethane and methanol (10 mL) with a volume ratio of 9:1. Dichloromethane solution containing 5% methanol was used as the eluent, and purification was carried out by silica gel column chromatography, resulting in 1 ,2,4-thiadiazol-5-amine as a white solid (1.4 g, 47% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 7.95 (s, 2H), 7.85 (s, 1H).LC/MS analysis conditions: 10%-99% acetonitrile (containing 0.035% trifluoroacetic acid)/water (containing 0.05% trifluoroacetic acid), observed m/z (M+1) = 102.1; retention time tR = 0.39 min.
References
[1] Patent: US2009/124655, 2009, A1. Location in patent: Page/Page column 14
[2] Patent: US2009/131440, 2009, A1. Location in patent: Page/Page column 18-19
[3] Patent: US2008/27067, 2008, A1. Location in patent: Page/Page column 259
5-Amino-1,2,4-thiadiazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Amino-1,2,4-thiadiazole manufacturers
- Product
- 5-Amino-1,2,4-thiadiazole 7552-07-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 150KG
- Release date
- 2019-07-01