(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

Product Name: (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
CAS No.: 80751-65-1
Chemical Name: (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
Synonyms: Cl-apb;Chloro-AP;SK&F 82958;SKF82958 HBr;SKF82958,SKF 82958;6H-Benzo[cd]pyren-7-one;(±)-SKF 82958;CHLORO-APB;(+/-)-SKF-82958 HYDROBROMIDE;(+/-)-Chloro-apbhydrobromide;(+/-)-CHLORO-APB HYDROBROMIDE
CBNumber: CB3251102
Molecular Formula: C19H20ClNO2
Formula Weight: 329.82
MOL File: 80751-65-1.mol

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(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Property

Boiling point:: 473.7±45.0 °C(Predicted)
Density: 1.234±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: H₂O: 3.7 mg/mL
form: solid
pka: 8.73±0.40(Predicted)
color: tan
Water Solubility: H2O: 3.7mg/mL
aqueous base: unstable
ethanol: soluble

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C130
Product name: Chloro-APB hydrobromide
Purity: solid
Packaging: 5mg
Price: $178
Updated: 2024/03/01

Sigma-Aldrich

Product number: C130
Product name: Chloro-APB hydrobromide
Purity: solid
Packaging: 25mg
Price: $244.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: C130
Product name: Chloro-APB hydrobromide
Purity: solid
Packaging: 100mg
Price: $2010
Updated: 2023/01/07

TRC

Product number: C364438
Product name: Chloro-APB hydrobromide
Packaging: 10mg
Price: $180
Updated: 2021/12/16

Usbiological

Product number: 466156
Product name: SKF 82958 Hydrobromide
Packaging: 5mg
Price: $355
Updated: 2021/12/16

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(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemical Properties,Usage,Production

Uses

Chloro-APB hydrobromide has been used to pharmacologically stimulate D1 dopamine receptors and study its influence on locomotor response in fat mass and obesity-associated protein (FTO) deficient dopamine D1 receptor-expressing medium spiny neurons (D1 MSNs) of mice.

Definition

ChEBI: 9-chloro-5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol is a benzazepine.

Biochem/physiol Actions

Chloro-APB hydrobromide, also known as SKF 82958, is a D1 dopamine receptor agonist. D1 receptor agonists prevent and reverse fentanyl-induced respiratory depression, without impairing opioid analgesia, in cats.

(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Suppliers

China 21 Switzerland 1 Ukraine 1 United Kingdom 1 United States 8 Global 32

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80751-65-1, (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDERelated Search:

2-(3-Chlorophenyl)ethylamine 3-CHLOROCATECHOL Dopamine 3-CHLORO-5-METHYLPHENOL 3-CHLORO-4-METHYLPHENOL Hordenine hydrochloride N,N-BIS(2-PHENYL-ETHYL)-N-METHYL-AMINE 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPIN-7-OL N,beta-Dimethylphenethylamine hydrochloride [2-(3-CHLORO-PHENYL)-ETHYL]-ETHYL-AMINE 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE N-ISOBUTYL-2-PROPEN-1-AMINE 6-CHLORO-2,3,4,5-TETRAHYDRO-1-(3-METHYLPHENYL)-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE [2-(3-CHLORO-PHENYL)-ETHYL]-METHYL-AMINE ethyl(1-phenylethyl)benzene

(±)-SKF 82958;CHLORO-APB

(+/-)-SKF-82958 HYDROBROMIDE

(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

6-CHLORO-N-ALLYL-SKF-38393 HYDROBROMIDE

SK&F 82958

(±)-SKF-82958 hydrobromide, 6-Chloro-N-allyl-SKF-38393 hydrobromide, (±)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

6-Chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diol

1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-

6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Cl-apb

SKF82958 HBr

3-allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol

(+/-)-CHLORO-APB HYDROBROMIDE

(+/-)-CHLORO-APB HYDROBROMIDE ((+/-)-SKF -82958 HBR)

1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-

(+/-)-Chloro-apbhydrobromide

Chloro-AP

6H-Benzo[cd]pyren-7-one

(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

SKF82958,SKF 82958

(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-P...

80751-65-1

C19H20ClNO2HBr