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Bis[(2-guanidino-4-thiazolyl)methyl]disulfide

Product Name
Bis[(2-guanidino-4-thiazolyl)methyl]disulfide
CAS No.
129083-44-9
Chemical Name
Bis[(2-guanidino-4-thiazolyl)methyl]disulfide
Synonyms
Famotidine disulfide;Famotidine Impurity 5;Bis[ (FaMotidine IMpurity);FaMotidine Related CoMpound E;Famotidine USP Related Compound E;Famotidine EP Impurity E (USP RC E);2,2'-[Disulfanediylbis-(methyleneth;Bis[(2-guanidino-4-thiazolyl)methyl]disulfide;Famotidine Impurity 5(Famotidine EP Impurity E);Famotidine EP Impurity E/ Famotidine Related Compound E
CBNumber
CB32512210
Molecular Formula
C10H14N8S4
Formula Weight
374.53
MOL File
129083-44-9.mol
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Bis[(2-guanidino-4-thiazolyl)methyl]disulfide Property

Melting point:
155-157°C
Boiling point:
601.0±65.0 °C(Predicted)
Density 
1.86±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
DMF (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
pka
8.77±0.70(Predicted)
color 
Off-White to Pale Beige
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Safety

HS Code 
2934990002
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1269254
Product name
Famotidine Related Compound E
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25MG
Price
$1490
Updated
2024/03/01
TRC
Product number
B439800
Product name
Bis[(2-guanidino-4-thiazolyl)methyl]disulfide(>85%Purity)(FamotidineImpurity)
Packaging
1mg
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
IB58076
Product name
Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide
Packaging
50mg
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
IB58076
Product name
Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide
Packaging
10mg
Price
$70
Updated
2021/12/16
Biosynth Carbosynth
Product number
IB58076
Product name
Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide
Packaging
25mg
Price
$125
Updated
2021/12/16
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Bis[(2-guanidino-4-thiazolyl)methyl]disulfide Chemical Properties,Usage,Production

Uses

A potential impurity in Famotidine (F102250)

Bis[(2-guanidino-4-thiazolyl)methyl]disulfide Preparation Products And Raw materials

Raw materials

Preparation Products

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Bis[(2-guanidino-4-thiazolyl)methyl]disulfide Suppliers

Canada 1 China 51 India 7 United Kingdom 2 United States 10 Global 71
Toronto Research Chemicals
Tel
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Fax
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Email
info@trc-canada.com
Country
Canada
ProdList
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Advantage
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129083-44-9, Bis[(2-guanidino-4-thiazolyl)methyl]disulfideRelated Search:

Famotidine EP Impurity A N-DesaMinosulfonyl-N-cyano FaMotidine FaMotidine AMide IMpurity FaMotidine Acid IMpurity Methyl Ester Famotidine Related Compound A Hydrochloride FaMotidine Acid IMpurity 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoylpropanamidine 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoyl propanamide FAMOTIDINE RELATED COMPOUND B Famotidine 3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile 3-Chloropropiononitrile (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride 2-(4-(CHLOROMETHYL)THIAZOL-2-YL)GUANIDINE Sulfamide 3-Hydroxypropionic acid 3-HYDROXYPROPIONAMIDE

  • Bis[(2-guanidino-4-thiazolyl)methyl]disulfide
  • Bis[(2-guanidino-4-thiazolyl)Methyl]disulfide (FaMotidine IMpurity)
  • Famotidine Related Compound E (25 mg) (2,2'-[4,4'-disulfanediylbis(methylene)bis(thiazole-4,2-diyl)]diguanidine)
  • N,N'''-[Dithiobis(Methylene-4,2-thiazolediyl)]bisguanidine
  • Bis[(2-guanidino-4-thiazolyl)Methyl]disulfide (85%) (FaMotidine IMpurity)
  • 2-[4-[[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methyldisulfanyl]methyl]-1,3-thiazol-2-yl]guanidine
  • 2,2'-[Disulfanediylbis-(methylenethiazole-4,2-diyl)]diguanidine
  • Famotidine USP Related Compound E
  • Bis[ (FaMotidine IMpurity)
  • Famotidine Impurity 5(Famotidine EP Impurity E)
  • FaMotidine Related CoMpound E
  • Famotidine EP Impurity E (USP RC E)
  • 2,2'-[Disulfanediylbis-(methyleneth
  • Guanidine, N,N'''-[dithiobis(methylene-4,2-thiazolediyl)]bis-
  • Bis[(2-guanidino-4-thiazolyl)methyl]disulfide (>85% Purity) (Famotidine Impurity)
  • Famotidine EP Impurity E/ Famotidine Related Compound E
  • 1,1'-(4,4'-(Disulfanediylbis(methylene))bis(thiazole-4,2-diyl))diguanidine
  • Famotidine Impurity 5
  • Famotidine Related Compound E (2,2''-[4,4''-disulfanediylbis(methylene)bis(thiazole-4,2-diyl)]diguani (1269254)
  • 2,2''-((Disulfanediylbis(methylene))bis(thiazole-4,2-diyl))diguanidine
  • 1,1'-(4,4'-(Disulfanediylbis(methylene))bis(thiazole-4,2-diyl))diguanidine (Famotidine Impurity)
  • Famotidine EP Impurity E (Famotidine USP Related Compound E)
  • Famotidine Related Compound-E / Famotidine EP Impurity-E
  • Famotidine disulfide
  • 1,1'-(4,4'-(Disulfanediylbis(methylene))bis(thiazole-4,2-diyl))diguanidine (Famotidine Impurity)
  • 129083-44-9
  • C10H14N8S4
  • Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
  • Sulfur & Selenium Compounds
  • Heterocycles
  • Impurities
  • Intermediates & Fine Chemicals
  • Pharmaceuticals