ChemicalBook > CAS DataBase List > Bis[(2-guanidino-4-thiazolyl)methyl]disulfide

Bis[(2-guanidino-4-thiazolyl)methyl]disulfide

Product Name: Bis[(2-guanidino-4-thiazolyl)methyl]disulfide
CAS No.: 129083-44-9
Chemical Name: Bis[(2-guanidino-4-thiazolyl)methyl]disulfide
Synonyms: Famotidine disulfide;Famotidine Impurity 5;Bis[ (FaMotidine IMpurity);FaMotidine Related CoMpound E;Famotidine USP Related Compound E;Famotidine EP Impurity E (USP RC E);2,2'-[Disulfanediylbis-(methyleneth;Bis[(2-guanidino-4-thiazolyl)methyl]disulfide;Famotidine Impurity 5(Famotidine EP Impurity E);Famotidine EP Impurity E/ Famotidine Related Compound E
CBNumber: CB32512210
Molecular Formula: C10H14N8S4
Formula Weight: 374.53
MOL File: 129083-44-9.mol

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Bis[(2-guanidino-4-thiazolyl)methyl]disulfide Property

Melting point:: 155-157°C
Boiling point:: 601.0±65.0 °C(Predicted)
Density: 1.86±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility: DMF (Slightly), Methanol (Slightly, Sonicated)
form: Solid
pka: 8.77±0.70(Predicted)
color: Off-White to Pale Beige
biological source: synthetic
InChI: InChI=1S/C10H14N8S4/c1-21-3-5(15-9(21)17-7(11)12)19-20-6-4-22(2)10(16-6)18-8(13)14/h3-4H,1-2H2,(H4,11,12,15,17)(H4,13,14,16,18)
InChIKey: UDPYMFXUBRDIAY-UHFFFAOYSA-N
SMILES: S(C1=CS(=C)C(NC(=N)N)=N1)SC1=CS(=C)C(NC(=N)N)=N1

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Safety

HS Code: 2934990002

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1269254
Product name: Famotidine Related Compound E
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 25MG
Price: $1300
Updated: 2025/07/31

TRC

Product number: B439800
Product name: Bis[(2-guanidino-4-thiazolyl)methyl]disulfide(>85%Purity)(FamotidineImpurity)
Packaging: 1mg
Price: $130
Updated: 2021/12/16

Biosynth Carbosynth

Product number: IB58076
Product name: Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide
Packaging: 50mg
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: IB58076
Product name: Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide
Packaging: 10mg
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: IB58076
Product name: Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide
Packaging: 25mg
Price: $125
Updated: 2021/12/16

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Bis[(2-guanidino-4-thiazolyl)methyl]disulfide Chemical Properties,Usage,Production

Uses

A potential impurity in Famotidine (F102250)

Bis[(2-guanidino-4-thiazolyl)methyl]disulfide Preparation Products And Raw materials

Raw materials

Preparation Products

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129083-44-9, Bis[(2-guanidino-4-thiazolyl)methyl]disulfideRelated Search:

Famotidine EP Impurity A N-DesaMinosulfonyl-N-cyano FaMotidine FaMotidine AMide IMpurity FaMotidine Acid IMpurity Methyl Ester Famotidine Related Compound A Hydrochloride FaMotidine Acid IMpurity 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoylpropanamidine 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoyl propanamide FAMOTIDINE RELATED COMPOUND B Famotidine 3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile 3-Chloropropiononitrile (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride 2-(4-(CHLOROMETHYL)THIAZOL-2-YL)GUANIDINE Sulfamide 3-Hydroxypropionic acid 3-HYDROXYPROPIONAMIDE

Bis[(2-guanidino-4-thiazolyl)methyl]disulfide

Bis[(2-guanidino-4-thiazolyl)Methyl]disulfide (FaMotidine IMpurity)

Famotidine Related Compound E (25 mg) (2,2'-[4,4'-disulfanediylbis(methylene)bis(thiazole-4,2-diyl)]diguanidine)

N,N'''-[Dithiobis(Methylene-4,2-thiazolediyl)]bisguanidine

Bis[(2-guanidino-4-thiazolyl)Methyl]disulfide (85%) (FaMotidine IMpurity)

2-[4-[[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methyldisulfanyl]methyl]-1,3-thiazol-2-yl]guanidine

2,2'-[Disulfanediylbis-(methylenethiazole-4,2-diyl)]diguanidine

Famotidine USP Related Compound E

Bis[ (FaMotidine IMpurity)

Famotidine Impurity 5(Famotidine EP Impurity E)

FaMotidine Related CoMpound E

Famotidine EP Impurity E (USP RC E)

2,2'-[Disulfanediylbis-(methyleneth

Guanidine, N,N'''-[dithiobis(methylene-4,2-thiazolediyl)]bis-

Bis[(2-guanidino-4-thiazolyl)methyl]disulfide (>85% Purity) (Famotidine Impurity)

Famotidine EP Impurity E/ Famotidine Related Compound E

1,1'-(4,4'-(Disulfanediylbis(methylene))bis(thiazole-4,2-diyl))diguanidine

Famotidine Impurity 5

Famotidine Related Compound E (2,2''-[4,4''-disulfanediylbis(methylene)bis(thiazole-4,2-diyl)]diguani (1269254)

2,2''-((Disulfanediylbis(methylene))bis(thiazole-4,2-diyl))diguanidine

1,1'-(4,4'-(Disulfanediylbis(methylene))bis(thiazole-4,2-diyl))diguanidine (Famotidine Impurity)

Famotidine EP Impurity E (Famotidine USP Related Compound E)

Famotidine disulfide

Famotidine Related Compound-E / Famotidine EP Impurity-E

129083-44-9

C10H14N8S4

Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds

Sulfur & Selenium Compounds

Heterocycles

Impurities

Intermediates & Fine Chemicals

Pharmaceuticals