Uses
ChemicalBook > CAS DataBase List > 3-HYDROXYPHTHALIC ANHYDRIDE

3-HYDROXYPHTHALIC ANHYDRIDE

Uses
Product Name
3-HYDROXYPHTHALIC ANHYDRIDE
CAS No.
37418-88-5
Chemical Name
3-HYDROXYPHTHALIC ANHYDRIDE
Synonyms
4-HYDROXY-ISOBENZOFURAN-1,3-DIONE;Nsc 80858;Brn 0135783;3-HydroxyphthaL;3-hydroxy-phthalicanhydrid;3-hydroxyphtalic anhydride;3-HYDROXYPHTHALIC ANHYDRIDE;Phthalic anhydride, 3-hydroxy-;4-hydroxy-3-isobenzofurandione;3-HYDROXYPHTHALIC ACID ANHYDRIDE
CBNumber
CB3253702
Molecular Formula
C8H4O4
Formula Weight
164.12
MOL File
37418-88-5.mol
More
Less

3-HYDROXYPHTHALIC ANHYDRIDE Property

Melting point:
199-202 °C (lit.)
Boiling point:
365.4±25.0 °C(Predicted)
Density 
1.624±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Acetonitrile (Slightly), DMSO (Slightly)
pka
6.25±0.20(Predicted)
form 
Powder
color 
White to beige
BRN 
135783
Stability:
Hygroscopic
InChIKey
CCTOEAMRIIXGDJ-UHFFFAOYSA-N
CAS DataBase Reference
37418-88-5(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
TI3300000
F 
21
HS Code 
29182900
Toxicity
mouse,LD50,intravenous,75mg/kg (75mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#08845,
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
308021
Product name
3-Hydroxyphthalic anhydride
Purity
98%
Packaging
1g
Price
$120.4
Updated
2024/03/01
TRC
Product number
H951270
Product name
3-Hydroxyphthalic anhydride
Packaging
2.5g
Price
$60
Updated
2021/12/16
SynQuest Laboratories
Product number
2H26-1-33
Product name
3-Hydroxyphthalic anhydride
Purity
97%
Packaging
5G
Price
$109
Updated
2021/12/16
Oakwood
Product number
222694
Product name
4-Hydroxyisobenzofuran-1,3-dione
Packaging
250mg
Price
$20
Updated
2021/12/16
BroadPharm
Product number
BP-13154
Product name
3-Hydroxyphthalic anhydride
Purity
98%
Packaging
250mg
Price
$35
Updated
2021/12/16
More
Less

3-HYDROXYPHTHALIC ANHYDRIDE Chemical Properties,Usage,Production

Uses

3-Hydroxyphthalic Anhydride is used to synthesize 3-Hydroxyphthalic Anhydride-modified human serum albumin which has high potency as a microbicide for prevention of the sexual transmission of HIV. It is also used as a reagent in organic synthesis of other compounds including that of inhibitors of NF-κB derived from thalidomide.

Chemical Properties

Beige powder

Uses

3-Hydroxyphthalic Anhydride is used to synthesize 3-Hydroxyphthalic Anhydride-modified human serum albumin whichhas high potency as a microbicide for prevention of the sexual transmission of HIV. It is also used as a reagent in organicsynthesis of other compounds including that of inhibitors of NF-κB derived from thalidomide.

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 5092, 1955 DOI: 10.1021/ja01624a042
Synthesis, p. 788, 1985 DOI: 10.1055/s-1985-31350

3-HYDROXYPHTHALIC ANHYDRIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-HYDROXYPHTHALIC ANHYDRIDE Suppliers

Belgium 1 China 215 Germany 4 India 4 Japan 1 South Korea 1 Switzerland 3 Ukraine 1 United Kingdom 7 United States 32 Global 269
shandong XuanHong Pharmaceutical Technology Co.,Ltd
Tel
0531-88801869 15562622698
Fax
0531-88801867
Email
sciencechem@163.com
Country
China
ProdList
274
Advantage
55
Chongqing TianyiHenghua Technology Co., Ltd.
Tel
15086758486; 15086758486
Fax
-
Email
chemtyhh@163.com
Country
China
ProdList
86
Advantage
58
Wuhan kemike Biomedical Technology Co., Ltd
Tel
027-87747081 18186681184
Email
1344475572@qq.com
Country
China
ProdList
7243
Advantage
58
Wuxi Kehua Biological Technology Co., Ltd.
Tel
0510-0510-86838766
Email
2258830676@qq.com
Country
China
ProdList
3835
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44700
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9492
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
18086
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Shanghai AmasPharm Co., Ltd.
Tel
021-54540637 18621091017
Fax
021-34978309
Email
sales@amaspharm.com
Country
China
ProdList
694
Advantage
62
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4550
Advantage
62
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 15343847665
Fax
QQ：3470079902
Email
huawenchem@163.com
Country
China
ProdList
3205
Advantage
55
Tianjin Branch Chong pharmaceutical intermediates Co., Ltd.
Tel
022-60116533 13207668525
Fax
022-60979672
Email
saleskc@scipharmacn.com
Country
China
ProdList
695
Advantage
58
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9454
Advantage
58
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7854
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3993
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5877
Advantage
58
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6740
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15885
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10063
Advantage
53
Shanghai Synteam Biochem CO.,ltd
Tel
+86-021-58380978 +86-18017016373
Fax
021-58380978
Email
info@systeambc.com
Country
China
ProdList
938
Advantage
50
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5917
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9767
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Quzhou Rundong Chemical (Technology) Co.
Tel
0570-8789886 18892685668
Fax
0570-8789985
Email
info@rundongchemical.com
Country
China
ProdList
3985
Advantage
60
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7978
Advantage
55
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9030
Advantage
60
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9638
Advantage
58
ATK CHEMICAL COMPANY LIMITED
Tel
3429815786 13301662590
Fax
+86-21-51619052
Email
sales@atkchemical.com
Country
China
ProdList
10004
Advantage
55
Nanjing XiLang Chemical Products Co., Ltd.
Tel
025-5276156 18936048580
Email
chemxilang@163.com
Country
China
ProdList
4003
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9934
Advantage
55
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9604
Advantage
55
Radiant Pharma & Tech. Co., Ltd
Tel
T:15050866711
Fax
QQ:2677337387
Email
wanglin.chen@radiant-pharma.com
Country
China
ProdList
466
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8019
Advantage
62
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131980
Advantage
58
Nanjing Klender Bio-Technology Co., Ltd.
Tel
025-52343882 18112933882
Fax
025-52343882
Email
sales@kldbio.com
Country
China
ProdList
2019
Advantage
55
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7580
Advantage
55
Jinan Winwind Biological Technology Co., Ltd
Tel
15153166971
Email
win-wind@hotmail.com
Country
China
ProdList
97
Advantage
58
Wuhan Netcom Electronic Commerce Limited
Tel
18064670521
Fax
0757-88210752
Email
2355935187@ycphar.com
Country
China
ProdList
4887
Advantage
58
BIO-PHARMACY (Wuhan) Co., Ltd.
Tel
0711-5919292 15307133740
Fax
0711-5919292
Email
3451683016@qq.com
Country
China
ProdList
1070
Advantage
58
Capot Chemical Co.,Ltd.
Tel
571-85586718 +8613336195806
Fax
+86-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
29797
Advantage
60
Aikon International Limited
Tel
025-66028182 18112977050
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15820
Advantage
58
More
Less

View Lastest Price from 3-HYDROXYPHTHALIC ANHYDRIDE manufacturers

Asia Chem I and E (Jiangsu) Co Ltd
Product
3-Hydroxyphthalic anhydride 37418-88-5
Price
US $125.58/Kg/Drum
Min. Order
25Kg/Drum
Purity
98.00%HPLC
Supply Ability
1ton/month
Release date
2021-09-17
Hebei Guanlang Biotechnology Co., Ltd.
Product
3-HYDROXYPHTHALIC ANHYDRIDE 37418-88-5
Price
US $10.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2021-05-17
Hebei Mojin Biotechnology Co., Ltd
Product
3-HYDROXYPHTHALIC ANHYDRIDE 37418-88-5
Price
US $100.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000KG
Release date
2023-08-24

37418-88-5, 3-HYDROXYPHTHALIC ANHYDRIDERelated Search:

3-AMINOPHTHALIC ACID HYDROCHLORIDE 3-IODOPHTHALIC ACID 1-Methyl-3-nitrophthalate 3-Oxocyclopentanecarboxylic acid 4-Hydroxyphthalic acid 3-AMINOPHTHALIC ACID 3-BOC-AMINO-2,6-DIOXOPIPERIDINE Luminol 3-HYDROXYPHTHALIC ANHYDRIDE 4-HYDROXYPHTHALIC ANHYDRIDE 3,6-DIACETOXYPHTHALIC ACID ANHYDRIDE AKOS 200-04 AKOS 220-67 AKOS 237-82 4,7-DIHYDROXY-2-BENZOFURAN-1,3-DIONE AKOS 215-94 AKOS 243-37 AKOS 212-66

  • 4-HYDROXY-ISOBENZOFURAN-1,3-DIONE
  • 3-HYDROXYPHTHALIC ACID ANHYDRIDE
  • 3-HYDROXYPHTHALIC ANHYDRIDE
  • 3-hydroxy-phthalicanhydrid
  • 4-hydroxy-3-isobenzofurandione
  • 1,3-Isobenzofurandione, 4-hydroxy-
  • Brn 0135783
  • Nsc 80858
  • Phthalic anhydride, 3-hydroxy-
  • 4-hydroxy-1,3-dihydro-2-benzofuran-1,3-dione
  • 4-Hydroxy-2-benzofuran-1,3-dione
  • 3-HYDROXYPHTHALIC ANHYDRIDE 97+%
  • 4-Hydroxy-1,3-isobenzofurandione
  • 3-HydroxyphthaL
  • 3-hydroxyphtalic anhydride
  • 3-HYDROXYPHTHALIC ANHYDRIDE ISO 9001：2015 REACH
  • 3-Hydroxyphthalic anhydride 4-Chlorophthalic anhydride
  • 37418-88-5
  • Organic Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Building Blocks
  • Anhydride Monomers
  • Monomers
  • Polymer Science
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Organic Building Blocks
  • Phthalic Acids, Esters and Derivatives
  • 37418-88-5