(R,R,R)-Aprepitant

Product Name: (R,R,R)-Aprepitant
CAS No.: 1148113-53-4
Chemical Name: (R,R,R)-Aprepitant
Synonyms: Aprepitant A;(R,R,R)-Aprepitant;(1R,2R,3R)-Aprepitant;"1R,2R,2R Aprepitant";Aprepitant impurity 04;Aprepitant EP Impurity E;Aprepitant Related CoMpound A;Aprepitant trans-1-enantiomer;Aprepitant USP RC A (R,R,R-Diasteromer);Aprepitant EP Impurity E/ (R,R,R)-Aprepitant
CBNumber: CB32557888
Molecular Formula: C23H21F7N4O3
Formula Weight: 534.43
MOL File: 1148113-53-4.mol

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(R,R,R)-Aprepitant Property

Density: 1.51±0.1 g/cm3(Predicted)
pka: 8.06±0.20(Predicted)

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Safety

HS Code: 2934990002

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1041915
Product name: Aprepitant Related Compound A
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 10MG
Price: $1300
Updated: 2024/03/01

TRC

Product number: A729785
Product name: (R,R,R)-Aprepitant
Packaging: 25mg
Price: $5095
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0027120
Product name: APREPITANT RELATED COMPOUND A
Purity: 95.00%
Packaging: 5MG
Price: $504.12
Updated: 2021/12/16

AK Scientific

Product number: 6464EM
Product name: (R,R,R)-Aprepitant
Packaging: 2mg
Price: $590
Updated: 2021/12/16

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(R,R,R)-Aprepitant Chemical Properties,Usage,Production

Uses

(R,R,R)-Aprepitant (Aprepitant EP Impurity E) is the (R,R,R)-enantiomer of Aprepitant (A729800), the key intermediate of Aprepitant in bulk drug and formulation samples of Aprepitant.

Application

(R,R,R)-Aprepitant (Aprepitant Related Compound A) is a USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

(R,R,R)-Aprepitant Preparation Products And Raw materials

Raw materials

Preparation Products

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(R,R,R)-Aprepitant Suppliers

Canada 1 China 60 India 5 United Kingdom 1 United States 7 Global 74

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1148113-53-4, (R,R,R)-AprepitantRelated Search:

Aprepitant Aprepitant Atorvastatin Related Compound D (20 mg) (Epoxide impurity, or 3-(4-Fluorobenzoyl)-2-isobutyryl-3-phenyl-oxirane-2- carboxylic acid phenylamide) Atorvastatin Ethyl Ester Atorvastatin Related Compound C Atorvastatin Methyl Ester Atorvastatin Epoxy Tetrahydrofuran IMpurity Atorvastatin Acetonide Atenolol 2-[4-(2,3-DIHYDROXYPROPOXY)PHENYL]ACETAMIDE Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide Atorvastatin tert-Butyl Ester 2,3-Dehydroxy Atorvastatin Sodium Salt 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt O-Methyl Atorvastatin Calcium Salt 5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one Aprepitant Impurity 11 HCl Aprepitant Impurity 2

(R,R,R)-Aprepitant

Aprepitant trans-1-enantiomer

Aprepitant Related Compound A (10 mg) (3-[[(2R,3R)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholino]methyl]-1H-1,2,4-triazol-5(4H)-one)

5-[[(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one

Aprepitant Related CoMpound A

Aprepitant EP Impurity E

Aprepitant A

Aprepitant USP RC A (R,R,R-Diasteromer)

(1R,2R,3R)-Aprepitant

3-(((2R,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one

Aprepitant impurity 5/Aprepitant EP Impurity E

Aripitant related substance A reference substance

3H-1,2,4-Triazol-3-one, 5-[[(2R,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-

5-(((2R,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

Aprepitant EP Impurity E/ (R,R,R)-Aprepitant

"1R,2R,2R Aprepitant"

Aprepitant Related Compound A (3-[[(2R,3R)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fl (1041915)

Aprepitant(R,R,R)-Isomer（Azilsartan Impurity 41）

Aprepitant impurity 04

Aprepitant RRR isomer (diastearomer)-(5-(((2R,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl) ethoxy)-3-(4-fluorophenyl) morpholino)methyl)-1,2-dihydro-1,2,4-triazol-3-one)

1148113-53-4

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