4SC-201
- Product Name
- 4SC-201
- CAS No.
- 864814-88-0
- Chemical Name
- 4SC-201
- Synonyms
- CS-304;RAS2410;4SC-201;ResMinostat;ResMinostat(4SC-201);ResMinostat (RAS2410);RESMINOSTAT; 4SC-201; RAS2410;4SC-201(resminostat,BYK408740);RAS2410;4SC-201;RAS 2410;RAS-2410;(E)-3-[1-[4-[(dimethylamino)methyl]phenyl]sulfonylpyrrol-3-yl]-N-hydroxyprop-2-enamide
- CBNumber
- CB32582958
- Molecular Formula
- C16H19N3O4S
- Formula Weight
- 349.4
- MOL File
- 864814-88-0.mol
4SC-201 Property
- Density
- 1.28±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Powder
- pka
- 8.68±0.23(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A4108
- Product name
- Resminostat(RAS2410)
- Packaging
- 5mg
- Price
- $173
- Updated
- 2021/12/16
- Product number
- A4108
- Product name
- Resminostat(RAS2410)
- Packaging
- 10mg
- Price
- $284
- Updated
- 2021/12/16
- Product number
- orb611518
- Product name
- Resminostat
- Packaging
- 100mg
- Price
- $690.2
- Updated
- 2021/12/16
- Product number
- A4108
- Product name
- Resminostat(RAS2410)
- Packaging
- 50mg
- Price
- $1010
- Updated
- 2021/12/16
- Product number
- orb611518
- Product name
- Resminostat
- Packaging
- 250mg
- Price
- $1208.7
- Updated
- 2021/12/16
4SC-201 Chemical Properties,Usage,Production
Uses
Resminostat is an oral histone deacetylase (HDAC) inhibitor. It inhibits proliferation and induces apoptosis in multiple myeloma (MM) cells.
Biological Activity
resminostat, also known as ras2410, is a potent inhibitor of histone deacetylase (hdac) classes i and ii (including hdac1, hdac3 and hdac6) with 50% inhibition concentration ic50 values ranging from 43 to 72 nmol/l. resminostate has the potential to be used for the treatment of multiple myeloma (mm) due to its ability to induce histone h4 hyperacetylation, and apoptosis (ic50 ranging from 2.5 to 3 μmol/l) in mm cells. recent study results have shown that, in mm cell lines, resminostat abrogates cell growth, suppresses proliferation and induce g0/g1 cell cycle arrest as well as interfering with akt signaling pathway by decreasing phosphorylation of 4e-bp1 and p70s6k.mandl-weber s, meinel fg, jankowsky r, oduncu f, schmidmaier r, baumann p. the novel inhibitor of histone deacetylase resminostat (ras2410) inhibits proliferation and induces apoptosis in multiple myeloma (mm) cells. br j haematol. 2010; 149(4):518-528.
4SC-201 Preparation Products And Raw materials
Raw materials
Preparation Products
4SC-201 Suppliers
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View Lastest Price from 4SC-201 manufacturers
- Product
- Resminostat 864814-88-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- Min98% HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2019-12-30