[(S,S)-Teth-TsDpen RuCl] Property

Melting point:

260-268℃

storage temp. 

2-8°C

form 

Powder

color 

orange

optical activity

[α]22/D +339°, c = 0.5% in chloroform

Sensitive 

Air & Moisture Sensitive

Safety

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

[(S,S)-Teth-TsDpen RuCl] Chemical Properties,Usage,Production

Uses

Catalyst for the asymmetric transfer hydrogenation of ketones

Uses

Chloro[N-[(1S,2S)-1,2-diphenyl-2-[(R)-[3-(η6-phenyl)propyl]amino-κN]ethyl]-4-methylbenzenesulfonamidato-κN]ruthenium StereoisomerC30 H31ClN2O2RuS is a catalyst for Asymmetric Transfer Hydrogenations of Ketones.

Uses

[(S,S)-Teth-TsDpen RuCl] is a catalyst for the asymmetric hydrogenation of ketones. It can be used as a catalyst:

• In the reduction of a ketone intermediate for the synthesis of esketamine.
• In asymmetric hydrogenation of acetylenic ketones.
• For the preparation of (3S,6S)-1,8-diphenylocta-1,7-diyne-3,6-diol starting from 1,8-diphenylocta-1,7-diyne-3,6-dione.

Reactions

Catalyst used for asymmetric -transfer hydrogenation.