1,7-NAPHTHYRIDIN-8-AMINE

Product Name: 1,7-NAPHTHYRIDIN-8-AMINE
CAS No.: 17965-82-1
Chemical Name: 1,7-NAPHTHYRIDIN-8-AMINE
Synonyms: 1,7phthyridin-8-ylamine;1,7-NAPHTHYRIDIN-8-AMINE;8-AMINO-1,7-NAPHTHYRIDINE;8-amino-1,7-naphthypridine;[1,7]Naphthyridin-8-ylaMine;8-Amino-1,7-naphthyridine 95+%;1,7-Naphthyridin-8-amine, 8-Amino-1,7-diazanaphthalene
CBNumber: CB3265183
Molecular Formula: C8H7N3
Formula Weight: 145.16
MOL File: 17965-82-1.mol

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1,7-NAPHTHYRIDIN-8-AMINE Property

Melting point:: 167-170°C
Boiling point:: 343.3±27.0 °C(Predicted)
Density: 1.292±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 5.54±0.30(Predicted)
form: solid
color: Yellow
CAS DataBase Reference: 17965-82-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,T
Risk Statements: 36/37/38-36-25
Safety Statements: 26-36/37/39-45
Hazard Note: Irritant
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: N373490
Product name: 1,7-Naphthyridin-8-amine
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: N373490
Product name: 1,7-Naphthyridin-8-amine
Packaging: 250mg
Price: $90
Updated: 2021/12/16

Apolloscientific

Product number: OR0830
Product name: 8-Amino-1,7-naphthyridine
Purity: 95%
Packaging: 250mg
Price: $54
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-1-W6
Product name: 8-Amino-1,7-naphthyridine
Packaging: 250mg
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: V3881
Product name: 1,7-Naphthyridin-8-amine
Packaging: 250mg
Price: $104
Updated: 2021/12/16

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1,7-NAPHTHYRIDIN-8-AMINE Chemical Properties,Usage,Production

Uses

1,7-Naphthyridin-8-amine is a useful chemical in organic synthesis.

Synthesis

452-58-4

56-81-5

17965-82-1

a. A mixture of 2,3-diaminopyridine (5.0 g, 45.9 mmol), glycerol (21.1 g, 229 mmol), sodium 3-nitrobenzenesulfonate (20.6 g, 91.7 mmol), and sulfuric acid (20 mL) was added to water (30 mL), and the reaction was stirred for 16 hours at 135°C. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently slowly poured into an ice-water mixture (150 g). After adjusting the pH of the mixture to neutral with base, it was extracted with ethyl acetate (3 x 100 mL). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography using petroleum ether/ethyl acetate (2:1, v/v) as eluent to afford 1,7-naphthyridin-8-amine as a yellow solid (2.6 g, 39% yield). eSI MS: m/z 146.1 [M + H]+.

References

[1] Patent: US2012/178748, 2012, A1. Location in patent: Page/Page column 47
[2] Patent: WO2017/14323, 2017, A1. Location in patent: Paragraph 0278

1,7-NAPHTHYRIDIN-8-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,7-NAPHTHYRIDIN-8-AMINE Suppliers

China 83 France 1 Germany 3 India 3 United Kingdom 10 United States 10 Global 110

Alchem Pharmtech,Inc.

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View Lastest Price from 1,7-NAPHTHYRIDIN-8-AMINE manufacturers

Career Henan Chemical Co

Product: 1,7-NAPHTHYRIDIN-8-AMINE 17965-82-1
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-01-30

17965-82-1, 1,7-NAPHTHYRIDIN-8-AMINERelated Search:

1,5-NAPHTHYRIDIN-4-AMINE Hemp seed protein 5,6,7,8-TETRAHYDRO-6-(PHEHYLMETHYL)-1,6-NAPHTHYRIDIN-3-AMINE 4-(1,7-NAPHTHYRIDIN-8-YLAMINO)-4-OXOBUTANOICACID 1,7-NAPHTHYRIDIN-8-AMINE 7-chloro-1,8-naphthyridin-2-amine N-PIPERIDIN-4-YL-2-(TRIFLUOROMETHYL)-1,6-NAPHTHYRIDIN-5-AMINE HYDROCHLORIDE MONOHYDRATE 1,6-NAPHTHYRIDIN-2-AMINE PEAKDALE 1018772 N-(1,7-NAPHTHYRIDIN-8-YL)-N'-[2-(TRIFLUOROMETHYL)PHENYL]UREA N-[(4-METHYLPHENYL)SULPHONYL]-N'-(1,7-NAPHTHYRIDIN-8-YL)UREA N,N-DIBENZOYL-1,7-NAPHTHYRIDIN-8-AMINE 5-(4-FLUOROPHENYL)-8-(4-[4-(METHYLSULFONYL)BENZOYL]PIPERAZIN-1-YL)-1,7-NAPHTHYRIDINE 8-[4-(2,4-DIFLUOROBENZOYL)PIPERAZIN-1-YL]-5-(3-THIENYL)-1,7-NAPHTHYRIDINE PEAKDALE 1018780 N-[4-(TRIFLUOROMETHYL)BENZOYL]-1,7-NAPHTHYRIDIN-8-AMINE 5-(4-FLUOROPHENYL)-8-[4-(MORPHOLIN-4-YLCARBONYL)PIPERAZIN-1-YL]-1,7-NAPHTHYRIDINE N,N-DI[3-(TRIFLUOROMETHYL)BENZOYL]-1,7-NAPHTHYRIDIN-8-AMINE

8-AMINO-1,7-NAPHTHYRIDINE

1,7-NAPHTHYRIDIN-8-AMINE

1,7phthyridin-8-ylamine

[1,7]Naphthyridin-8-ylaMine

1,7-Naphthyridin-8-amine, 8-Amino-1,7-diazanaphthalene

8-amino-1,7-naphthypridine

8-Amino-1,7-naphthyridine 95+%

17965-82-1

C8H7N3