AMT HYDROCHLORIDE
- Product Name
- AMT HYDROCHLORIDE
- CAS No.
- 21463-31-0
- Chemical Name
- AMT HYDROCHLORIDE
- Synonyms
- 4H-1;AMT HCL;AMT HYDROCHLORIDE;2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HCL;2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HYDROCHLORIDE;5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZIN-2-AMINE, HYDROCHLORIDE
- CBNumber
- CB3266443
- Molecular Formula
- C5H11ClN2S
- Formula Weight
- 166.67
- MOL File
- 21463-31-0.mol
AMT HYDROCHLORIDE Property
- Melting point:
- 146-150°C
- storage temp.
- 0-6°C
- solubility
- DMF: >8 mg/ml; DMSO: >16 mg/ml; Ethanol: >25 mg/ml; Water: >25 mg/ml
- form
- A crystalline solid
- Water Solubility
- Soluble to 10 mM in water
Safety
- HS Code
- 29309099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 81010
- Product name
- AMT (hydrochloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 81010
- Product name
- AMT (hydrochloride)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- 81010
- Product name
- AMT (hydrochloride)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $448
- Updated
- 2024/03/01
- Product number
- 81010
- Product name
- AMT (hydrochloride)
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $711
- Updated
- 2024/03/01
- Product number
- 0871
- Product name
- AMThydrochloride
- Packaging
- 50
- Price
- $527
- Updated
- 2021/12/16
AMT HYDROCHLORIDE Chemical Properties,Usage,Production
Description
AMT is a potent, relatively selective inhibitor of iNOS with a Ki of 4.2 nM in mouse macrophages. It inhibits other isoforms of NOS, but at higher concentrations; the IC50 values for rat nNOS and bovine eNOS are 34 and 150 nM, respectively.
Chemical Properties
white to off-white powder
Uses
AMT Hydrochloride is a potent and selective inhibitors of inducible nitric oxide synthase, which may lead to therapeutic applications in the treatment of inflammatory and autoimmune diseases.
Biological Activity
Potent, selective and reversible inhibitor of iNOS (IC 50 = 3.6 nM; approximately 30 and 40 times selective over nNOS and eNOS respectively).
storage
Desiccate at +4°C