RG-7388

Product Name: RG-7388
CAS No.: 1229705-06-9
Chemical Name: RG-7388
Synonyms: Idasanutlin;RG7388;Pexidartinib Hydrochloride;RG-7388;RG 7388;Ro 5503781;RG-7388 USP/EP/BP;RG-7388, Idasanutlin;Idasanutlin (RG-7388);RG 7388; RG-7388; RG7388
CBNumber: CB32666681
Molecular Formula: C31H29Cl2F2N3O4
Formula Weight: 616.48
MOL File: 1229705-06-9.mol

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RG-7388 Property

Melting point:: >261° (dec.)
Boiling point:: 737.3±60.0 °C(Predicted)
Density: 1.40±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 4.11±0.10(Predicted)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 21532
Product name: RG7388
Purity: ≥98%
Packaging: 1mg
Price: $47
Updated: 2024/03/01

Cayman Chemical

Product number: 21532
Product name: RG7388
Purity: ≥98%
Packaging: 5mg
Price: $206
Updated: 2024/03/01

Cayman Chemical

Product number: 21532
Product name: RG7388
Purity: ≥98%
Packaging: 10mg
Price: $339
Updated: 2024/03/01

Cayman Chemical

Product number: 21532
Product name: RG7388
Purity: ≥98%
Packaging: 25mg
Price: $564
Updated: 2024/03/01

Tocris

Product number: 6904
Product name: Idasanutlin
Purity: ≥98%(HPLC)
Packaging: 50
Price: $609
Updated: 2021/12/16

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RG-7388 Chemical Properties,Usage,Production

Description

Potent MDM2 inhibitor with an IC50 = 6 nM in binding assay and 30 nM in cancer cell proliferation assay. Induces p53 stabilisation, cell cycle arrest and apoptosis in cancer cells expression wildtype p53. Displays inhibition of tumor growth in the SJSA1 tumor xenograft model. Also inhibits MDR-1 at high concentrations.

Uses

Idasanutlin is an MDM2 inihibtor, blocking the p53 protein-protein interaction and may be used in anti-cancer treatments.

storage

Store at -20°C

RG-7388 Preparation Products And Raw materials

Raw materials

Preparation Products

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RG-7388 Suppliers

China 122 India 4 United States 13 Global 139

Changzhou Chenhong Biotechnology Co., Ltd.

Tel: 0519-85788828 13775037613
Email: sales@chemrenpharm.com
Country: China
ProdList: 3553
Advantage: 58

Shanghai Chaolan Chemical Technology Center

Tel: QQ:65489617 15618227136
Fax: 21-5161 9052
Email: info@SuperLan-chem.com
Country: China
ProdList: 9445
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

Tongchuang Pharma(Suzhou). Co., Ltd.

Tel: 0512-63263366 18912765016
Fax: 0512-6326 3366
Email: tongtf110@sina.com
Country: China
ProdList: 997
Advantage: 62

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4647
Advantage: 58

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1494
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2784
Advantage: 58

TargetMol Chemicals Inc.

Tel: 021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7934
Advantage: 58

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View Lastest Price from RG-7388 manufacturers

Career Henan Chemical Co

Product: RG-7388 1229705-06-9
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100g , 1kg, 5kg , 50kg
Release date: 2020-01-07

1229705-06-9, RG-7388Related Search:

PD 0325901 Nutlin 3a PD184352 (CI-1040) 7-hydroxy-4-Methyl-2-oxo-2H-1-Benzopyran-8-carboxaldehyde Ponatinib BEZ235 (NVP-BEZ235, Dactolisib)

Idasanutlin

4-[[[(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl]carbonyl]amino]-3-methoxybenzoic acid

RG 7388

RG7388

RG-7388

RG-7388, Idasanutlin

Idasanutlin (RG-7388)

RG 7388; RG-7388; RG7388

Pexidartinib Hydrochloride

4-[[(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimet

4-{[(2R,3S,4R,5S)-4-(4-Chloro-2-fluoro-phenyl)-3-(3-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoic acid

Ro 5503781

Benzoic acid, 4-[[[(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl]carbonyl]amino]-3-methoxy-

4-{[(3s,4r,5s)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-D-prolyl]amino}-3-methoxybenzoic acid

RG-7388 USP/EP/BP

4-[(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-amido]-3-methoxybenzoic acid

4-((2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamido)-3-methoxybenzoic acid

4-{(3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(2-fluoro-4-chlorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-D-prolylamino}-3-methoxy-benzoic acid

1229705-06-9

C31H29Cl2F2N3O4

Inhibitors