ChemicalBook > CAS DataBase List > XL-388

XL-388

Product Name
XL-388
CAS No.
1251156-08-7
Chemical Name
XL-388
Synonyms
XL388;XL-388;CS-772;XL 388;XL388, >=98%;XL-388;XL 388;XL-388 USP/EP/BP;Carbamazepine 298-46-4 three units, HPLC Purity : XL388;inhibit,XL388,XL 388,Mammalian target of Rapamycin,Inhibitor,mTOR,XL-388;(7-(6-Aminopyridin-3-yl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)(3-fluoro-2-methyl-4-(methy
CBNumber
CB32666702
Molecular Formula
C23H22FN3O4S
Formula Weight
455.5
MOL File
1251156-08-7.mol
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XL-388 Property

Melting point:
>188oC (dec.)
Boiling point:
738.6±60.0 °C(Predicted)
Density 
1.354±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
6.22±0.13(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1239
Product name
XL388
Purity
≥98% (HPLC)
Packaging
5MG
Price
$58.4
Updated
2024/03/01
Cayman Chemical
Product number
20237
Product name
XL388
Purity
≥98%
Packaging
5mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
20237
Product name
XL388
Purity
≥98%
Packaging
10mg
Price
$230
Updated
2024/03/01
Cayman Chemical
Product number
20237
Product name
XL388
Purity
≥98%
Packaging
25mg
Price
$505
Updated
2024/03/01
Cayman Chemical
Product number
20237
Product name
XL388
Purity
≥98%
Packaging
50mg
Price
$903
Updated
2024/03/01
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XL-388 Chemical Properties,Usage,Production

Uses

XL388 is a highly potent, orally bioavailable, selective, ATP-competitive mammalian target of rapamycin (mTOR) inhibitor. XL388 has shown significant and dose-dependent antitumor activity in athymic nude mice implanted with human tumor xenografts.

XL-388 Preparation Products And Raw materials

Raw materials

Preparation Products

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XL-388 Suppliers

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1251156-08-7, XL-388Related Search:

XL-765,SAR245409 Foretinib (GSK1363089) 5-Bromo-4-chloro-3-indolyl-beta-D-galactoside XL147 1,1-Cyclopropanedicarboxamide, N-(4-fluorophenyl)-N'-[4-[[7-methoxy-6-[(methylamino)carbonyl]-4-quinolinyl]oxy]phenyl]- 4-Cyanopyridine 2-Amino-4-(trifluoromethyl)pyridine DI-2-PYRIDYL KETONE XL413 (BMS-863233) BMS-852927 2-methoxyethyl 4-((4-(4-chlorophenoxy)-3,5-difluorophenyl)sulfonyl)-3-(hydroxycarbamoyl)piperazine-1-carboxylate XL888 XL019 XL 228 AZD-8055 OSI-027 Cediranib Ribociclib

  • Methanone, [7-(6-amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-
  • [7-(6-Amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone XL388
  • XL388, >=98%
  • (7-(6-Aminopyridin-3-yl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)(3-fluoro-2-methyl-4-(methy
  • XL 388
  • XL388
  • XL-388
  • [7-(6-Amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone
  • Carbamazepine 298-46-4 three units, HPLC Purity : XL388
  • XL-388;XL 388
  • CS-772
  • XL-388 USP/EP/BP
  • (7-(6-Aminopyridin-3-yl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)(3-fluoro-2-methyl-4-(methylsulfonyl)phenyl)methanone
  • inhibit,XL388,XL 388,Mammalian target of Rapamycin,Inhibitor,mTOR,XL-388
  • 1251156-08-7
  • PI3K/Akt/mTOR
  • Akt
  • mTOR
  • PI3K
  • Inhibitors