ChemicalBook > CAS DataBase List > 4-Cyanopyridine

4-Cyanopyridine

Product Name
4-Cyanopyridine
CAS No.
100-48-1
Chemical Name
4-Cyanopyridine
Synonyms
ISONICOTINONITRILE;4-PYRIDINECARBONITRILE;Pyridine-4-carbonitrile;4-cyanopyridin;4-CYANOPYRIDINE;Cyanopyridine,4-;AKOS BBS-00004486;4-Pyridinenitrile;Isonicotinonitril;TIMTEC-BB SBB008923
CBNumber
CB0688145
Molecular Formula
C6H4N2
Formula Weight
104.11
MOL File
100-48-1.mol
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4-Cyanopyridine Property

Melting point:
76-79 °C(lit.)
Boiling point:
196 °C
Density 
1.1145 (rough estimate)
vapor pressure 
41.9Pa at 25℃
refractive index 
1.5242 (estimate)
Flash point:
88 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
40g/l
pka
pK1:1.90(+1) (25°C)
form 
Crystals or Powder
color 
White to off-white
Water Solubility 
3.2 g/100ml (16.4 ºC)
BRN 
107712
Exposure limits
NIOSH: IDLH 25 mg/m3
Stability:
Stable. Incompatible with strong bases, strong oxidizing agents, strong acids.
InChIKey
GPHQHTOMRSGBNZ-UHFFFAOYSA-N
LogP
0.46 at 25℃
CAS DataBase Reference
100-48-1(CAS DataBase Reference)
NIST Chemistry Reference
4-Pyridinecarbonitrile(100-48-1)
EPA Substance Registry System
4-Pyridinecarbonitrile (100-48-1)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
36/37-24/25
RIDADR 
3276
WGK Germany 
3
TSCA 
Yes
PackingGroup 
III
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C95005
Product name
4-Pyridinecarbonitrile
Purity
98%
Packaging
100g
Price
$23.7
Updated
2023/01/07
TCI Chemical
Product number
C0457
Product name
4-Cyanopyridine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$14
Updated
2023/01/07
TCI Chemical
Product number
C0457
Product name
4-Cyanopyridine
Purity
>98.0%(GC)(T)
Packaging
100g
Price
$35
Updated
2023/01/07
Alfa Aesar
Product number
A10286
Product name
4-Cyanopyridine, 98%
Packaging
100g
Price
$21.4
Updated
2021/12/16
Alfa Aesar
Product number
A10286
Product name
4-Cyanopyridine, 98%
Packaging
10g
Price
$18
Updated
2021/12/16
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4-Cyanopyridine Chemical Properties,Usage,Production

Chemical Properties

beige solid

Chemical Properties

The cyanopyridines are as follows: 2-cyano-: A white to tan liquid or solid. Almond odor. Boiling point=2213℃ ; freezing/melting point=27℃ ; flash point=89℃ . 3-cyano-: a colorless liquid or gray crystal- line solid.

Uses

4-Cyanopyridine is used as an intermediate in organic synthesis and pharmaceutical substances like isonicotinylhydrazide, which is used in the treatment of tuberculosis. It is used as a precursor for the preparation of isonicotinic acid and 4-diemthylaminopyridine (DMAP). It is involved in the synthesis of 6-methyl-2-pyridin-4-yl-pyrimidin-4-ylamine by reacting with acetonitrile.

Potential Exposure

Limits in Air NIOSH IDLH525 mg/m3 NIOSH REL: (nitriles) 2 ppm, Ceiling Concentration, not to be exceeded in any 15-minute work period.

Shipping

UN3276 Nitriles, liquid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required, Potential Inhalation Hazard (Special Provision 5).

Incompatibilities

Oxidizing agents, such as perchlorates, peroxides, and permanganates. Nitriles may polymerize in the presence of metals and some metal compounds. They are incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions. Nitriles are generally incompatible with other oxidizing agents such as peroxides and epoxides. The combination of bases and nitriles can produce hydrogen cyanide. Nitriles are hydrolyzed in both aqueous acid and base to give car- boxylic acids (or salts of carboxylic acids). These reactions generate heat. Peroxides convert nitriles to amides. Nitriles can react vigorously with reducing agents. Acetonitrile and propionitrile are soluble in water, but nitriles higher than propionitrile have low aqueous solubility. They are also insoluble in aqueous acids .

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4-Cyanopyridine Suppliers

Shanghai Xinyue Chemical Co., Ltd.
Tel
18116267768
Email
645908973@qq.com
Country
China
ProdList
70
Advantage
58
Shandong Tianshili Biological Technology Co. LTD
Tel
18663779269 18765889670
Fax
18663779269
Email
TSL15098984171@163.com
Country
China
ProdList
180
Advantage
58
Weifang QianJin Fine Chemical Co., Ltd.
Tel
18753684562
Fax
0536-8897109
Email
1577399715@qq.com
Country
China
ProdList
1941
Advantage
55
Shandong Xinhe new material co.,ltd
Tel
15662672320
Email
2360124261@qq.com
Country
China
ProdList
302
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40242
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15861
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30133
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
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View Lastest Price from 4-Cyanopyridine manufacturers

Hebei Duling International Trade Co. LTD
Product
4-Cyanopyridine 100-48-1
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000tons
Release date
2022-10-15
Hebei Guanlang Biotechnology Co., Ltd.
Product
4-Cyanopyridine 100-48-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-11-04
Baoji Guokang Bio-Technology Co., Ltd.
Product
4-Cyanopyridine 100-48-1
Price
US $68.00/Kg/Bag
Min. Order
1KG
Purity
98%
Supply Ability
10T
Release date
2021-06-04

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