Lansoprazole (sodiuM)

Product Name: Lansoprazole (sodiuM)
CAS No.: 226904-00-3
Chemical Name: Lansoprazole (sodiuM)
Synonyms: AG-1749 sodium;Lansoprazole (sodiuM);Lansoprazole (sodiuM) USP/EP/BP;2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]benzimidazol-1-ide;sodium,2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]benzimidazol-1-ide
CBNumber: CB32677070
Molecular Formula: C16H13F3N3NaO2S
Formula Weight: 393.36
MOL File: 226904-00-3.mol

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Lansoprazole (sodiuM) Property

storage temp.: Store at -20°C
solubility: insoluble in H2O; ≥15.05 mg/mL in EtOH; ≥58.9 mg/mL in DMSO
form: solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ApexBio Technology

Product number: B1290
Product name: Lansoprazolesodium
Packaging: 10mM(in 1mL Ethanol)
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-1848
Product name: Lansoprazolesodium
Packaging: 500mg
Price: $50
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0014457
Product name: LANSOPRAZOLE SODIUM
Purity: 95.00%
Packaging: 1G
Price: $195.3
Updated: 2021/12/16

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Lansoprazole (sodiuM) Chemical Properties,Usage,Production

Biological Activity

lansoprazole sodium is a proton-pump inhibitor (ppi) and also can inhibit cytochrome p450 [1].lansoprazole sodium is a substituted benzimidazole and has been widely used as acid inhibitory agent for treatment of disorders related to gastric acid secretion. lansoprazole sodium has been exhibited to inhibit stomach acid by blocking the h+/k+atpase system at the secretory surface of gastric parietal cells. as the human p450 enzymes including cyp2c9,2c19, 2d6 and 3a4, in addition, lansoprazole sodium has been reported to have the competitively inhibitory effect on the activity of cyp2c9 in hlm with a ki value of 21μm. lansoprazole sodium has been found to be potent cyp2c19 inhibitor with a ki value of about 1μm in both hlm and rcyp2c19 tests. besides, lansoprazole sodium has been revealed to inhibit the activities if cyp2d6 and cyp3a4 with ic50 values of both>200μm [1].

References

[1] li xq1, andersson tb, ahlström m, weidolf l.comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome p450 activities. drug metab dispos. 2004 aug;32(8):821-7.

Lansoprazole (sodiuM) Preparation Products And Raw materials

Raw materials

Preparation Products

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Lansoprazole (sodiuM) Suppliers

China 31 India 4 United States 6 Global 41

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View Lastest Price from Lansoprazole (sodiuM) manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Lansoprazole sodium 226904-00-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Lansoprazole sodium 226904-00-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

226904-00-3, Lansoprazole (sodiuM)Related Search:

Lansoprazole Lansoprazole Impurity I Standard Lansoprazole Impurity G(5-Hydroxy Lansoprazole) Lansoprazole Impurity 3 2-(((3-Methyl-4-nitropyridin-2-yl)Methyl)sulfinyl)-1H- benzo[d]iMidazole Lansoprazole IMpurity I Lansoprazole Sulfone N-Oxide 2-(3-methyl -4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methylthio-1h-benzimidazole (Lansoprazole sulfide) 2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole 2-[[[4-(2,2,2-Trifluoroethoxy)-3-Methyl-1-oxopyridin-2-yl]Methyl]sulfanyl]-1H-benziMidazole lansoprazole Impurity 29 lansoprazole Impurity 23 Lansoprazole pellet's LANSOPRAZOLE SULFONE LANSOPRAZOLE-D4 1-Methyl-12-thioxopyrido[1',2':3,4] Lansoprazole 99% Lansoprazole IMpurity H

2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]benzimidazol-1-ide

Lansoprazole (sodiuM)

Lansoprazole (sodiuM) USP/EP/BP

sodium,2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]benzimidazol-1-ide

AG-1749 sodium

226904-00-3

C16H13F3N3NaO2S