Lansoprazole (sodiuM)
- Product Name
- Lansoprazole (sodiuM)
- CAS No.
- 226904-00-3
- Chemical Name
- Lansoprazole (sodiuM)
- Synonyms
- AG-1749 sodium;Lansoprazole (sodiuM);Lansoprazole (sodiuM) USP/EP/BP;2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]benzimidazol-1-ide;sodium,2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]benzimidazol-1-ide
- CBNumber
- CB32677070
- Molecular Formula
- C16H13F3N3NaO2S
- Formula Weight
- 393.36
- MOL File
- 226904-00-3.mol
Lansoprazole (sodiuM) Property
- storage temp.
- Store at -20°C
- solubility
- insoluble in H2O; ≥15.05 mg/mL in EtOH; ≥58.9 mg/mL in DMSO
- form
- solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B1290
- Product name
- Lansoprazolesodium
- Packaging
- 10mM(in 1mL Ethanol)
- Price
- $50
- Updated
- 2021/12/16
- Product number
- CS-1848
- Product name
- Lansoprazolesodium
- Packaging
- 500mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- API0014457
- Product name
- LANSOPRAZOLE SODIUM
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $195.3
- Updated
- 2021/12/16
Lansoprazole (sodiuM) Chemical Properties,Usage,Production
Biological Activity
lansoprazole sodium is a proton-pump inhibitor (ppi) and also can inhibit cytochrome p450 [1].lansoprazole sodium is a substituted benzimidazole and has been widely used as acid inhibitory agent for treatment of disorders related to gastric acid secretion. lansoprazole sodium has been exhibited to inhibit stomach acid by blocking the h+/k+atpase system at the secretory surface of gastric parietal cells. as the human p450 enzymes including cyp2c9,2c19, 2d6 and 3a4, in addition, lansoprazole sodium has been reported to have the competitively inhibitory effect on the activity of cyp2c9 in hlm with a ki value of 21μm. lansoprazole sodium has been found to be potent cyp2c19 inhibitor with a ki value of about 1μm in both hlm and rcyp2c19 tests. besides, lansoprazole sodium has been revealed to inhibit the activities if cyp2d6 and cyp3a4 with ic50 values of both>200μm [1].
References
[1] li xq1, andersson tb, ahlström m, weidolf l.comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome p450 activities. drug metab dispos. 2004 aug;32(8):821-7.
Lansoprazole (sodiuM) Preparation Products And Raw materials
Raw materials
Preparation Products
Lansoprazole (sodiuM) Suppliers
View Lastest Price from Lansoprazole (sodiuM) manufacturers
- Product
- Lansoprazole sodium 226904-00-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Lansoprazole sodium 226904-00-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09