ChemicalBook > CAS DataBase List > Shz-1

Shz-1

Product Name
Shz-1
CAS No.
326886-05-9
Chemical Name
Shz-1
Synonyms
Shz-1;(E)-N-(5-bromo-2-hydroxybenzylidene)benzenesulfonohydrazide;Benzenesulfonic acid [(5-bromo-2-hydroxyphenyl)methylene]hydrazide;2-[(5-BroMo-2-hydroxyphenyl)Methylene]hydrazide Benzenesulfonic Acid;Benzenesulfonic acid, 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide;sarcomeric tropomyosin,Shz 1,inhibit,cardiac-specific,Shz1,Inhibitor,Nkx2.5 expression,cardiogenic molecule,Shz-1
CBNumber
CB32677984
Molecular Formula
C13H11BrN2O3S
Formula Weight
355.21
MOL File
326886-05-9.mol
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Shz-1 Property

Boiling point:
503.9±60.0 °C(Predicted)
Density 
1.58±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble10mg/mL, clear
form 
powder
pka
7.79±0.48(Predicted)
color 
white to beige
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
36/37/39
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
15211
Product name
Shz-1
Purity
≥98%
Packaging
1mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
15211
Product name
Shz-1
Purity
≥98%
Packaging
5mg
Price
$107
Updated
2024/03/01
Cayman Chemical
Product number
15211
Product name
Shz-1
Purity
≥98%
Packaging
10mg
Price
$144
Updated
2024/03/01
Cayman Chemical
Product number
15211
Product name
Shz-1
Purity
≥98%
Packaging
50mg
Price
$595
Updated
2024/03/01
TRC
Product number
B685180
Product name
2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazideBenzenesulfonicAcid
Packaging
25mg
Price
$265
Updated
2021/12/16
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Shz-1 Chemical Properties,Usage,Production

Description

SHZ-1 (326886-05-9) triggers cardiac mRNA and protein expression in a variety of embryonic and adult stem/progenitor cells including human mobilized peripheral blood mononuclear cells (M-PBMC).1?A lead compound for the discovery of drugs which promote myocardial repair/regeneration by activating cardiac differentiation in M-PBMC. Cell permeable.

Uses

2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide Benzenesulfonic Acid, is a sulfonylhydrazone that activates cardiac differentiation, inducing the expression of early cardiac genes in mouse pluripotent and embryonic stem cells in vitro at low micromolar concentrations.

References

1) Sadek?et al. (2008),?Cardiogenic small molecules that enhanced myocardial repair by stem cells; Proc. Natl. Acad. Sci. USA,?105?6063

Shz-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Shz-1 Suppliers

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326886-05-9, Shz-1Related Search:

(+/-)-Verapamil hydrochloride MITOQ Dofetilide Nicardipine hydrochloride Sodium isethionate

  • Shz-1
  • 2-[(5-BroMo-2-hydroxyphenyl)Methylene]hydrazide Benzenesulfonic Acid
  • Benzenesulfonic acid [(5-bromo-2-hydroxyphenyl)methylene]hydrazide
  • (E)-N-(5-bromo-2-hydroxybenzylidene)benzenesulfonohydrazide
  • sarcomeric tropomyosin,Shz 1,inhibit,cardiac-specific,Shz1,Inhibitor,Nkx2.5 expression,cardiogenic molecule,Shz-1
  • Benzenesulfonic acid, 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide
  • 326886-05-9
  • Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds