Azido-peg4-pfp ester
- Product Name
- Azido-peg4-pfp ester
- CAS No.
- 1353012-00-6
- Chemical Name
- Azido-peg4-pfp ester
- Synonyms
- N3-PEG4-PFP;N3-PEG4-OPFP;N3-PEG4-PFP ESTER;N3-PEG4-CH2CH2COOPFP;Azido-PEG5-PFP ester;Azido-peg4-pfp ester;N3-PEG4-C2-Pfp ester;perfluorophenyl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate
- CBNumber
- CB32680054
- Molecular Formula
- C17H20F5N3O6
- Formula Weight
- 457.35
- MOL File
- 1353012-00-6.mol
Azido-peg4-pfp ester Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
Safety
- HS Code
- 2942000090
N-Bromosuccinimide Price
- Product number
- A847510
- Product name
- Azido-peg4-pfpester
- Packaging
- 10mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- A847510
- Product name
- Azido-peg4-pfpester
- Packaging
- 25mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- BP-20556
- Product name
- Azido-PEG4-PFPester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- POL0002364
- Product name
- AZIDO-PEG4-PFP ESTER
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.02
- Updated
- 2021/12/16
- Product number
- BIPG1165
- Product name
- Azido-PEG5-PFPester
- Packaging
- 100mg
- Price
- $544
- Updated
- 2021/12/16
Azido-peg4-pfp ester Chemical Properties,Usage,Production
Description
Azido-PEG4-PFP ester is a click reagent containing an azide group and a PFP moiety. The azide group enables Click Chemistry. The PFP ester is can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules, comparing with NHS ester, PFP ester is more stable.. The hydrophilic PEG spacer adds to the water solubility of this reagent.
Uses
N3-PEG4-C2-Pfp ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-Pfp ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
Non-cleavable Linker
Azido-peg4-pfp ester Preparation Products And Raw materials
Raw materials
Preparation Products
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