(R)-2-(methoxycarbonylamino)-2-phenylacetic acid
- Product Name
- (R)-2-(methoxycarbonylamino)-2-phenylacetic acid
- CAS No.
- 50890-96-5
- Chemical Name
- (R)-2-(methoxycarbonylamino)-2-phenylacetic acid
- Synonyms
- Moc-D-Phg;Moc-D-Phg-OH;Velpatasvir Impurity 28;MOC-D-phenylglycine acid;(R)-2-(methoxycarbonylamino)-2-phenyl;(R)-2-(methoxycarbonylamino)-2-phenylaceticaci;(R)-2-(methoxycarbonylamino)-2-phenylacetic acid;(αR)-α-[(Methoxycarbonyl)amino]benzeneacetic acid;(R)-2-(Methoxycarbonylamino)-2-phenylethanoic acid;(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetic acid
- CBNumber
- CB32681677
- Molecular Formula
- C10H11NO4
- Formula Weight
- 209.2
- MOL File
- 50890-96-5.mol
(R)-2-(methoxycarbonylamino)-2-phenylacetic acid Property
- Melting point:
- 120 °C
- Boiling point:
- 391.3±35.0 °C(Predicted)
- Density
- 1.283±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 3.96±0.10(Predicted)
- color
- White to Almost white
- optical activity
- Consistent with structure
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M3293
- Product name
- N-Methoxycarbonyl-D-phenylglycine
- Packaging
- 25G
- Price
- $25
- Updated
- 2025/07/31
- Product number
- M3293
- Product name
- N-Methoxycarbonyl-D-phenylglycine
- Packaging
- 100G
- Price
- $68
- Updated
- 2025/07/31
- Product number
- M342968
- Product name
- (R)-2-((Methoxycarbonyl)amino)-2-phenylaceticAcid
- Packaging
- 50mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- CS-0036426
- Product name
- (R)-2-((Methoxycarbonyl)amino)-2-phenylaceticacid
- Purity
- >97.0%
- Packaging
- 100g
- Price
- $56
- Updated
- 2021/12/16
- Product number
- CS-0036426
- Product name
- (R)-2-((Methoxycarbonyl)amino)-2-phenylaceticacid
- Purity
- >97.0%
- Packaging
- 500g
- Price
- $167
- Updated
- 2021/12/16
(R)-2-(methoxycarbonylamino)-2-phenylacetic acid Chemical Properties,Usage,Production
Uses
(R)-2-((Methoxycarbonyl)amino)-2-phenylacetic acid is a Glycine.html" class="link-product" target="_blank">Glycine (HY-Y0966) derivative[1].
Synthesis
875-74-1
79-22-1
50890-96-5
D-Phenylglycine (10.0 g, 66.1 mmol) and sodium hydroxide (21.2 g, 265 mmol) were dissolved in water (60 mL) at 0°C and stirred until completely dissolved. Subsequently, methyl chloroformate (10.2 mL, 133 mmol) was added slowly and dropwise over 20 minutes. The reaction mixture was continued to be stirred at 0°C for 1 hour. Upon completion of the reaction, it was acidified with concentrated hydrochloric acid (25 mL, 300 mmol) to pH < 2. The acidic aqueous phase was extracted with ethyl acetate (3 x 100 mL), the organic phases were combined and dried over anhydrous magnesium sulfate. After filtration to remove the desiccant, the organic phase was concentrated under reduced pressure to afford N-methoxycarbonyl-D-phenylglycine (Int-2a, 12.6 g, 91% yield), which could be used for subsequent reactions without further purification.
References
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368
(R)-2-(methoxycarbonylamino)-2-phenylacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-2-(methoxycarbonylamino)-2-phenylacetic acid Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from (R)-2-(methoxycarbonylamino)-2-phenylacetic acid manufacturers
- Product
- (R)-2-(methoxycarbonylamino)-2-phenylacetic acid 50890-96-5
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-22
- Product
- (R)-2-(methoxycarbonylamino)-2-phenylacetic acid 50890-96-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 97%
- Supply Ability
- 100kg
- Release date
- 2023-06-30
- Product
- Moc-D-phenylglycine 50890-96-5
- Price
- US $48.00-40.00/KG
- Min. Order
- 1化验
- Purity
- 99%
- Supply Ability
- 2tons
- Release date
- 2021-06-04