ChemicalBook > CAS DataBase List > Methotrexate α-Methyl Ester

Methotrexate α-Methyl Ester

Product Name
Methotrexate α-Methyl Ester
CAS No.
66147-29-3
Chemical Name
Methotrexate α-Methyl Ester
Synonyms
Methotrexate Impurity I;Methotrexate EP Impurity I;JYFDQHNTJJOKAS-AWEZNQCLSA-N;Methotrexate-a-Methyl Ester;Methotrexate Impurity 9(EP-I);Methotrexate-1-monomethyl ester;Methotrexate alpha-methyl ester;Methotrexate related compound I;Methotrexate α-Methyl Ester (Impurity I);Methotrexate α-Methyl Ester (Impurity I)
CBNumber
CB32695971
Molecular Formula
C21H24N8O5
Formula Weight
468.47
MOL File
66147-29-3.mol
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Methotrexate α-Methyl Ester Property

solubility 
Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
form 
Solid
color 
Light Yellow to Dark Orange
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
IM71454
Product name
Methotrexate-1-monomethyl ester
Packaging
10mg
Price
$650
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
52129
Product name
Methotrexateα-MethylEster
Packaging
10mg
Price
$650
Updated
2021/12/16
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Methotrexate α-Methyl Ester Chemical Properties,Usage,Production

Uses

Methotrexate α-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.

Methotrexate α-Methyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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66147-29-3, Methotrexate α-Methyl EsterRelated Search:

L-Glutamic acid, N-[N-[N-[N-[4-[[(2, 4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-.gamma.-gluta myl]-L-.gamma.-glutamyl]-L-.gamma.-glutamyl]- L-Glutamic acid, N-(N-(4-(((2,4-diamino-6-pteridinyl)methyl)methyl- methotrexate-gamma-dimethylamide 7-HYDROXY METHOTREXATE Methotrexate impurity 4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID Methotrexate γ-Methyl Ester METHOTREXATE-D3 Aminopterin L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- D(-)-AMETHOPTERIN Methotrexate Related Compound E (50 mg) (4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoic acid, hemihydrochloride) 2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINE N-(4-(METHYLAMINO)BENZOYL)-L-GLUTAMIC ACID L-Glutamic acid der. 4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid Methotrexate METHOTREXATE DIMETHYL ESTER

  • JYFDQHNTJJOKAS-AWEZNQCLSA-N
  • Methotrexate EP Impurity I
  • Methotrexate Impurity 9(EP-I)
  • Methotrexate α-Methyl Ester (Impurity I)
  • Methotrexate EP Impurity I（Amethopterin EP Impurity I）
  • (4S)-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
  • Methotrexate EP Impurity I/Methotrexate 1-Methyl Ester/Methotrexate α-Methyl Ester/(4S)-4-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
  • Methotrexate EP Impurity I (Methotrexate-1-Monomethyl Ester)
  • Methotrexate-1-monomethyl ester
  • Methotrexate Impurity I
  • L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 1-methyl ester
  • (S)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-methoxy-5-oxopentanoic acid
  • Methotrexate Impurity 9（Methotrexate EP Impurity I）
  • Methotrexate α-Methyl Ester，(S)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-methoxy-5-oxopentanoic acid
  • Methotrexate-a-Methyl Ester
  • Methotrexate α-Methyl Ester (Impurity I)
  • Methotrexate alpha-methyl ester
  • Methotrexate related compound I
  • 66147-29-3
  • Aromatics, Chiral Reagents, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals