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beta-Cyclodextrin hydrate

Product Name
beta-Cyclodextrin hydrate
CAS No.
68168-23-0
Chemical Name
beta-Cyclodextrin hydrate
Synonyms
CD;GRD4;ALPS5;β-CycL;IDDM12;CELIAC3;U in HNO3 1%;odextrin hydrate;CYCLOHEPTAAMYLOSE;10ug/l each of Ba
CBNumber
CB3270383
Molecular Formula
C42H70O35
Formula Weight
1134.98
MOL File
68168-23-0.mol
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beta-Cyclodextrin hydrate Property

Melting point:
>260 °C (dec.)(lit.)
alpha 
161 º (c=1, H2O 25 ºC)
storage temp. 
Refrigerator
solubility 
Water (Slightly)
form 
Crystalline Powder
color 
White
optical activity
[α]20/D +142°, c = 1 in H2O (Dry basis)
Water Solubility 
18.5 g/L (25 ºC)
Merck 
14,2718
BRN 
5915513
InChIKey
WHGYBXFWUBPSRW-JXMPPWEANA-N
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Safety

Safety Statements 
24/25
WGK Germany 
2
RTECS 
GU2293000
TSCA 
Yes
HS Code 
35051000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
856088
Product name
β-Cyclodextrin hydrate
Purity
99%
Packaging
5g
Price
$39.7
Updated
2025/07/31
Sigma-Aldrich
Product number
856088
Product name
β-Cyclodextrin hydrate
Purity
99%
Packaging
25g
Price
$63.5
Updated
2025/07/31
Cayman Chemical
Product number
23387
Product name
β-Cyclodextrin (hydrate)
Packaging
25g
Price
$48
Updated
2024/03/01
Cayman Chemical
Product number
23387
Product name
β-Cyclodextrin (hydrate)
Packaging
50g
Price
$89
Updated
2024/03/01
Sigma-Aldrich
Product number
856088
Product name
β-Cyclodextrin hydrate
Purity
99%
Packaging
100g
Price
$193
Updated
2025/07/31
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beta-Cyclodextrin hydrate Chemical Properties,Usage,Production

Description

β-Cyclodextrin (β-CD) is a cyclic oligosaccharide that contains seven D-(+)-glucopyranose units and has been used to improve the aqueous solubility of various compounds, especially those containing a phenyl group. The circular arrangement of its glucose units produces a torus-shaped ring configuration in which the CH2 groups and ether linkages of the molecule face the hollow interior, resulting in a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. When combined in solution with other compounds, the nonpolar aromatic portions of that compound interact with the nonpolar interior of the β-CD molecule, thus isolating the aromatic portion of the molecule from the water and thereby increasing its aqueous solubility.

Chemical Properties

white crystalline powder

Uses

beta-Cyclodextrin hydrate forms clathrates. Produces a water-soluble complex with dansyl chloride for the fluorescent labeling of proteins. It is used in pharmaceutical research, as pharmaceutical intermediates and also as chemical reagents.

General Description

β-cyclodextrin (β-CD), a well-known macrocyclic oligosaccharide member of the CD family, is composed of seven D-glucose units connected via α(1→4) glycosidic bonds. Its ability to form several inclusion complexes with organic as well as inorganic compounds makes it a potential candidate in solid and solution state determinations.

Purification Methods

Recrystallise β-cyclodextrin from water and dry it for 12hours in a vacuum at 110o, or 24hours in a vacuum at 70o. The purity is assessed by TLC on cellulose containing a fluorescent indicator. [Taguchi, J Am Chem Soc 108 2705 1986, Tabushi et al. J Am Chem Soc 108 4514 1986, Orstam & Ross J Phys Chem 91 2739 1987.] [Beilstein 19 IV 6287, 19/12 V 801.]

References

[1] HOFFMAN T. Book Review: The Nicholas Effect: A Boy’s Gift to the World[J]. Journal of transplant coordination?: official publication of the North American Transplant Coordinators Organization (NATCO), 1999, 9 1: 281-281. DOI: 10.1177/090591999900900414
[2] G B WILLIAMSON  J D W. Bacterial degradation of juglone?: Evidence against allelopathy?[J]. Journal of Chemical Ecology, 1990, 16 5: 1739-1742. DOI: 10.1007/bf01014105
[3] VENKATRAMANA M. RAO . Co-solubilization of poorly soluble drugs by micellization and complexation[J]. International Journal of Pharmaceutics, 2006, 319 1: Pages 98-106. DOI: 10.1016/j.ijpharm.2006.03.042

beta-Cyclodextrin hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from beta-Cyclodextrin hydrate manufacturers

Shijiazhuang Byine Trading Co.,ltd
Product
Beta Cyclodextrin Hydrate 68168-23-0
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2025-11-25
Hebei Chuanghai Biotechnology Co., Ltd
Product
beta-Cyclodextrin hydrate 68168-23-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-29
airuikechemical co., ltd.
Product
Beta-Cyclodextrin hydrate 68168-23-0
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200 tons
Release date
2024-04-07

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