ChemicalBook > CAS DataBase List > PTC-209 (hydrobroMide)

PTC-209 (hydrobroMide)

Product Name
PTC-209 (hydrobroMide)
CAS No.
1217022-63-3
Chemical Name
PTC-209 (hydrobroMide)
Synonyms
CS-1314;PTC-209HBR;PTC-209 HBr ,S7539;PTC-209 (hydrobroMide);N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-1,3-thiazol-2-amine;2-Thiazolamine, N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-, hydrobromide
CBNumber
CB32705094
Molecular Formula
C17H14Br3N5OS
Formula Weight
576.10296
MOL File
1217022-63-3.mol
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PTC-209 (hydrobroMide) Property

storage temp. 
Store at -20°C
solubility 
≥ 22.9mg/mL in DMSO with gentle warming
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P839850
Product name
PTC-209Hydrobromide
Packaging
25mg
Price
$415
Updated
2021/12/16
ApexBio Technology
Product number
B4971
Product name
PTC209HBr
Packaging
2mg
Price
$89
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
48442
Product name
PTC-209HBr
Packaging
5mg
Price
$610
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
48442
Product name
PTC-209HBr
Packaging
25mg
Price
$875
Updated
2021/12/16
Crysdot
Product number
CD31004245
Product name
PTC-209hydrobromide
Purity
98+%
Packaging
5mg
Price
$72
Updated
2021/12/16
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PTC-209 (hydrobroMide) Chemical Properties,Usage,Production

Uses

PTC-209 is a potent and selective BMI-1 inhibitor. It results in irreversible reduction of cancer-initiating cells (CICs).

in vivo

PTC-209 (60 mg/kg body weight; subcutaneously; once a day for 11 days) significantly reduces tumor volume[2].

Animal Model:Nude mice (male, aged 8-10 weeks, HCT1116 cell-derived tumor)[1]
Dosage:60 mg/kg body weight
Administration:Subcutaneously; once a day for 11 days
Result:Significantly reduced tumor volume.

PTC-209 (hydrobroMide) Preparation Products And Raw materials

Raw materials

Preparation Products

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1217022-63-3, PTC-209 (hydrobroMide)Related Search:


  • PTC-209 (hydrobroMide)
  • PTC-209HBR
  • 2-Thiazolamine, N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-, hydrobromide
  • CS-1314
  • N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-1,3-thiazol-2-amine
  • PTC-209 HBr ,S7539
  • 1217022-63-3
  • C17H13Br2N5OSHBr
  • C17H14Br3N5OS
  • Inhibitors