ChemicalBook > CAS DataBase List > PTC-209 (hydrobroMide)
PTC-209 (hydrobroMide)
- Product Name
- PTC-209 (hydrobroMide)
- CAS No.
- 1217022-63-3
- Chemical Name
- PTC-209 (hydrobroMide)
- Synonyms
- CS-1314;PTC-209HBR;PTC-209 HBr ,S7539;PTC-209 (hydrobroMide);N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-1,3-thiazol-2-amine;2-Thiazolamine, N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-, hydrobromide
- CBNumber
- CB32705094
- Molecular Formula
- C17H14Br3N5OS
- Formula Weight
- 576.10296
- MOL File
- 1217022-63-3.mol
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PTC-209 (hydrobroMide) Property
- storage temp.
- Store at -20°C
- solubility
- ≥ 22.9mg/mL in DMSO with gentle warming
- form
- Solid
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
TRC
- Product number
- P839850
- Product name
- PTC-209Hydrobromide
- Packaging
- 25mg
- Price
- $415
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B4971
- Product name
- PTC209HBr
- Packaging
- 2mg
- Price
- $89
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 48442
- Product name
- PTC-209HBr
- Packaging
- 5mg
- Price
- $610
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 48442
- Product name
- PTC-209HBr
- Packaging
- 25mg
- Price
- $875
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31004245
- Product name
- PTC-209hydrobromide
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $72
- Updated
- 2021/12/16
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PTC-209 (hydrobroMide) Chemical Properties,Usage,Production
Uses
PTC-209 is a potent and selective BMI-1 inhibitor. It results in irreversible reduction of cancer-initiating cells (CICs).
in vivo
PTC-209 (60 mg/kg body weight; subcutaneously; once a day for 11 days) significantly reduces tumor volume[2].
| Animal Model: | Nude mice (male, aged 8-10 weeks, HCT1116 cell-derived tumor)[1] |
| Dosage: | 60 mg/kg body weight |
| Administration: | Subcutaneously; once a day for 11 days |
| Result: | Significantly reduced tumor volume. |
PTC-209 (hydrobroMide) Preparation Products And Raw materials
Raw materials
Preparation Products
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