1-Boc-4-Propylaminopiperidine
- Product Name
- 1-Boc-4-Propylaminopiperidine
- CAS No.
- 301225-58-1
- Chemical Name
- 1-Boc-4-Propylaminopiperidine
- Synonyms
- 4-Propylamino-1-Boc;1-BOC-4-PROPYLAMINOPIPERIDINE;N-Boc-4-propylaminopiperidine;4-PROPYLAMINO-1-BOC-PIPERIDINE;tert-butyl 4-(propylamino)piperidine-1-carboxylate;4-(Prop-1-ylamino)piperidine, N1-BOC protected 97%;4-PROPYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-Piperidinecarboxylic acid, 4-(propylamino)-, 1,1-dimethylethyl ester
- CBNumber
- CB3270611
- Molecular Formula
- C13H26N2O2
- Formula Weight
- 242.36
- MOL File
- 301225-58-1.mol
1-Boc-4-Propylaminopiperidine Property
- Boiling point:
- 322.6±35.0 °C(Predicted)
- Density
- 0.99±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 10.25±0.20(Predicted)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B662063
- Product name
- 1-Boc-4-Propylaminopiperidine
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- V5013
- Product name
- 1-Boc-4-propylaminopiperidine
- Packaging
- 10g
- Price
- $173
- Updated
- 2021/12/16
- Product number
- 4H51-1-0U
- Product name
- 4-(Prop-1-ylamino)piperidine, N1-Boc protected
- Packaging
- 10g
- Price
- $322
- Updated
- 2021/12/16
- Product number
- 4H51-1-0U
- Product name
- 4-(Prop-1-ylamino)piperidine, N1-Boc protected
- Packaging
- 5G
- Price
- $216
- Updated
- 2021/12/16
- Product number
- CHM0002642
- Product name
- 4-(PROP-1-YLAMINO)PIPERIDINE, N1-BOC PROTECTED
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $1916.15
- Updated
- 2021/12/16
1-Boc-4-Propylaminopiperidine Chemical Properties,Usage,Production
Synthesis
107-10-8
79099-07-3
301225-58-1
Step A: N-tert-butoxycarbonyl-4-piperidone (5 g, 25 mmol), n-propylamine (3.69 mL, 45 mmol), acetic acid (1.43 mL, 25 mmol), and sodium triacetoxyborohydride (7.95 g, 37.5 mmol) were dissolved in dichloromethane (100 mL) and the reaction was stirred for 16 h at room temperature. After completion of the reaction, the reaction mixture was washed with deionized water (50 mL) and then with saturated sodium bicarbonate solution. The aqueous phase was back-extracted with dichloromethane (20 mL), and all organic phases were combined, dried with anhydrous magnesium sulfate, and concentrated under reduced pressure to give 1-N-Boc-4-propylaminopiperidine 6 g in 95% yield.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 18, p. 2475 - 2479
[2] Patent: US6498161, 2002, B1
[3] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 1, p. 336 - 343
1-Boc-4-Propylaminopiperidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-Boc-4-Propylaminopiperidine manufacturers
- Product
- 1-Boc-4-Propylaminopiperidine 301225-58-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10 tons
- Release date
- 2020-01-10