ChemicalBook > CAS DataBase List > 1-Boc-4-Propylaminopiperidine

1-Boc-4-Propylaminopiperidine

Product Name
1-Boc-4-Propylaminopiperidine
CAS No.
301225-58-1
Chemical Name
1-Boc-4-Propylaminopiperidine
Synonyms
4-Propylamino-1-Boc;1-BOC-4-PROPYLAMINOPIPERIDINE;N-Boc-4-propylaminopiperidine;4-PROPYLAMINO-1-BOC-PIPERIDINE;tert-butyl 4-(propylamino)piperidine-1-carboxylate;4-(Prop-1-ylamino)piperidine, N1-BOC protected 97%;4-PROPYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-Piperidinecarboxylic acid, 4-(propylamino)-, 1,1-dimethylethyl ester
CBNumber
CB3270611
Molecular Formula
C13H26N2O2
Formula Weight
242.36
MOL File
301225-58-1.mol
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1-Boc-4-Propylaminopiperidine Property

Boiling point:
322.6±35.0 °C(Predicted)
Density 
0.99±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
10.25±0.20(Predicted)
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B662063
Product name
1-Boc-4-Propylaminopiperidine
Packaging
50mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
V5013
Product name
1-Boc-4-propylaminopiperidine
Packaging
10g
Price
$173
Updated
2021/12/16
SynQuest Laboratories
Product number
4H51-1-0U
Product name
4-(Prop-1-ylamino)piperidine, N1-Boc protected
Packaging
10g
Price
$322
Updated
2021/12/16
SynQuest Laboratories
Product number
4H51-1-0U
Product name
4-(Prop-1-ylamino)piperidine, N1-Boc protected
Packaging
5G
Price
$216
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0002642
Product name
4-(PROP-1-YLAMINO)PIPERIDINE, N1-BOC PROTECTED
Purity
95.00%
Packaging
25G
Price
$1916.15
Updated
2021/12/16
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1-Boc-4-Propylaminopiperidine Chemical Properties,Usage,Production

Synthesis

107-10-8

79099-07-3

301225-58-1

Step A: N-tert-butoxycarbonyl-4-piperidone (5 g, 25 mmol), n-propylamine (3.69 mL, 45 mmol), acetic acid (1.43 mL, 25 mmol), and sodium triacetoxyborohydride (7.95 g, 37.5 mmol) were dissolved in dichloromethane (100 mL) and the reaction was stirred for 16 h at room temperature. After completion of the reaction, the reaction mixture was washed with deionized water (50 mL) and then with saturated sodium bicarbonate solution. The aqueous phase was back-extracted with dichloromethane (20 mL), and all organic phases were combined, dried with anhydrous magnesium sulfate, and concentrated under reduced pressure to give 1-N-Boc-4-propylaminopiperidine 6 g in 95% yield.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 18, p. 2475 - 2479
[2] Patent: US6498161, 2002, B1
[3] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 1, p. 336 - 343

1-Boc-4-Propylaminopiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Boc-4-Propylaminopiperidine Suppliers

Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Chengdu Forest Science and Technology Development Co., Ltd.
Tel
18030648795
Fax
028-61777050
Email
sales@cdforestchem.com
Country
China
ProdList
1998
Advantage
58
Wuhan TCASChem Technology Co., Ltd.
Tel
027-86697669 13986148687
Fax
86-027-86697669
Email
sales@tcaschem.com
Country
China
ProdList
3991
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Xingui Biotechnology Co., Ltd.
Tel
15121041756
Email
xingui2022@126.com
Country
China
ProdList
9979
Advantage
58
Tianjing Geneston Bio-tech Co.,Ltd.
Tel
022-60131465 18920720807
Fax
022-58558581
Email
zishan_1986@163.com
Country
China
ProdList
743
Advantage
58
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12000
Advantage
58
Chengdu J&B Technology Co., Ltd.
Tel
028-61186694 15608078506
Fax
028-61186694
Email
609128801@qq.com
Country
China
ProdList
837
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
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View Lastest Price from 1-Boc-4-Propylaminopiperidine manufacturers

Career Henan Chemical Co
Product
1-Boc-4-Propylaminopiperidine 301225-58-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10 tons
Release date
2020-01-10