ChemicalBook > CAS DataBase List > 1-Boc-4-Propylaminopiperidine

1-Boc-4-Propylaminopiperidine

Product Name
1-Boc-4-Propylaminopiperidine
CAS No.
301225-58-1
Chemical Name
1-Boc-4-Propylaminopiperidine
Synonyms
4-Propylamino-1-Boc;1-BOC-4-PROPYLAMINOPIPERIDINE;N-Boc-4-propylaminopiperidine;4-PROPYLAMINO-1-BOC-PIPERIDINE;tert-butyl 4-(propylamino)piperidine-1-carboxylate;4-(Prop-1-ylamino)piperidine, N1-BOC protected 97%;4-PROPYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-Piperidinecarboxylic acid, 4-(propylamino)-, 1,1-dimethylethyl ester
CBNumber
CB3270611
Molecular Formula
C13H26N2O2
Formula Weight
242.36
MOL File
301225-58-1.mol
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1-Boc-4-Propylaminopiperidine Property

Boiling point:
322.6±35.0 °C(Predicted)
Density 
0.99±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
10.25±0.20(Predicted)
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B662063
Product name
1-Boc-4-Propylaminopiperidine
Packaging
50mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
V5013
Product name
1-Boc-4-propylaminopiperidine
Packaging
10g
Price
$173
Updated
2021/12/16
SynQuest Laboratories
Product number
4H51-1-0U
Product name
4-(Prop-1-ylamino)piperidine, N1-Boc protected
Packaging
5G
Price
$216
Updated
2021/12/16
SynQuest Laboratories
Product number
4H51-1-0U
Product name
4-(Prop-1-ylamino)piperidine, N1-Boc protected
Packaging
10g
Price
$322
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0002642
Product name
4-(PROP-1-YLAMINO)PIPERIDINE, N1-BOC PROTECTED
Purity
95.00%
Packaging
25G
Price
$1916.15
Updated
2021/12/16
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1-Boc-4-Propylaminopiperidine Chemical Properties,Usage,Production

Synthesis

107-10-8

79099-07-3

301225-58-1

Step A: N-tert-butoxycarbonyl-4-piperidone (5 g, 25 mmol), n-propylamine (3.69 mL, 45 mmol), acetic acid (1.43 mL, 25 mmol), and sodium triacetoxyborohydride (7.95 g, 37.5 mmol) were dissolved in dichloromethane (100 mL) and the reaction was stirred for 16 h at room temperature. After completion of the reaction, the reaction mixture was washed with deionized water (50 mL) and then with saturated sodium bicarbonate solution. The aqueous phase was back-extracted with dichloromethane (20 mL), and all organic phases were combined, dried with anhydrous magnesium sulfate, and concentrated under reduced pressure to give 1-N-Boc-4-propylaminopiperidine 6 g in 95% yield.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 18, p. 2475 - 2479
[2] Patent: US6498161, 2002, B1
[3] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 1, p. 336 - 343

1-Boc-4-Propylaminopiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Boc-4-Propylaminopiperidine Suppliers

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View Lastest Price from 1-Boc-4-Propylaminopiperidine manufacturers

Career Henan Chemical Co
Product
1-Boc-4-Propylaminopiperidine 301225-58-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10 tons
Release date
2020-01-10