isofebrifugin
- Product Name
- isofebrifugin
- CAS No.
- 32434-44-9
- Chemical Name
- isofebrifugin
- Synonyms
- NSC 290495;isoferifugine;isofebrifugin;Isofebrifugine;cis-Febrifugine;alpha-Dichroine;ISOFEBRIFUGINE (B604866K055);Isofebrifugine, 10 mM in DMSO;3-[[(3aS,7aS)-Octahydro-2-hydroxyfuro[3,2-b]pyridin-2-yl]methyl]-4(3H)-quinazolinone;3-[(3aS,7aS)-2-Hydroxyperhydrofuro[3,2-b]pyridin-2-ylmethyl]-3,4-dihydroquinazolin-4-one
- CBNumber
- CB32715446
- Molecular Formula
- C16H19N3O3
- Formula Weight
- 301.34
- MOL File
- 32434-44-9.mol
isofebrifugin Property
- Melting point:
- 129-130 °C
- Boiling point:
- 519.8±58.0 °C(Predicted)
- Density
- 1.48±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 12.01±0.20(Predicted)
- color
- White to off-white
- InChI
- InChI=1S/C16H19N3O3/c20-15-11-4-1-2-5-12(11)18-10-19(15)9-16(21)8-13-14(22-16)6-3-7-17-13/h1-2,4-5,10,13-14,17,21H,3,6-9H2/t13-,14-,16-/m0/s1
- InChIKey
- YLYLCQRQSRDSQR-DZKIICNBSA-N
- SMILES
- N1C2=C(C=CC=C2)C(=O)N(C[C@@]2(O)O[C@@]3([H])CCCN[C@@]3([H])C2)C=1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 300478
- Product name
- ISOFEBRIFUGINE
- Packaging
- 20mg
- Price
- $665
- Updated
- 2021/12/16
- Product number
- orb259322
- Product name
- ISOFEBRIFUGINE (B604866K055)
- Purity
- 98%
- Packaging
- 20mg
- Price
- $666.4
- Updated
- 2021/12/16
- Product number
- CS-0032113
- Product name
- Isofebrifugine
- Packaging
- 5mg
- Price
- $336
- Updated
- 2021/12/16
- Product number
- orb259322
- Product name
- ISOFEBRIFUGINE (B604866K055)
- Purity
- 98%
- Packaging
- 10mg
- Price
- $513.4
- Updated
- 2021/12/16
- Product number
- CS-0032113
- Product name
- Isofebrifugine
- Packaging
- 10mg
- Price
- $571
- Updated
- 2021/12/16
isofebrifugin Chemical Properties,Usage,Production
Chemical Properties
White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dried root of Dichroa febrifuga Lour.
Uses
Isofebrifugine is a natural quinazolinone alkaloid with important physiological activities and good pharmacological effects. Antimalarial effect[1].
References
[1] Kobayashi S, et al. Catalytic Asymmetric Synthesis of Antimalarial Alkaloids Febrifugine and Isofebrifugine and Their Biological Activity.J Org Chem. 1999 Sep 3;64(18):6833-6841. DOI:10.1021/jo990877k
isofebrifugin Preparation Products And Raw materials
Raw materials
Preparation Products
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