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tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate

Product Name
tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate
CAS No.
452339-71-8
Chemical Name
tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate
Synonyms
BNKY020-VT02;Vilanterol Impurity 37;Vilanterol Impurity 30;tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl;tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoeth...;tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamate;Tert-butyl 2- (2,2-dimethyl-4H-1,3-benzodoxin-6-yl) -2-oxoethylcarbamate;tert-Butyl N-(2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl)carbamate;tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate;Tert - butyl 2-(2,2- dimethyl -4H-1,3- benzodioxin -6- yl )-2- Oxoethylcarb - N -amate
CBNumber
CB32716160
Molecular Formula
C17H23NO5
Formula Weight
321.37
MOL File
452339-71-8.mol
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tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate Property

Boiling point:
489.1±45.0 °C(Predicted)
Density 
1.134±0.06 g/cm3(Predicted)
pka
10.92±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

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tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate Chemical Properties,Usage,Production

Uses

Tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate is a Vilanterol impurity. Vilanterol is a novel and selective agonist of β2-ar.

Synthesis

Trifluoroacetic acid (10.2 mL) was added to di-(tert-butyl)2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl) -2-oxoethyliminodicarbonic acid at 20°C (46.37 g) in a stirred solution of dichloromethane (500 mL) and stirred for 4 hours. Aqueous sodium hydroxide solution (0.5 M, 400 mL) was added to the reaction solution, stirred for half an hour, and separated. The organic layer was washed with water (500 mL), dried, concentrated, and recrystallized from ether to obtain tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate 15.15g, yield 43 %.

tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate Suppliers

China 72 India 1 Global 73
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View Lastest Price from tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamate 452339-71-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
100tons
Release date
2023-09-13
Anhui Yiao New Material Technology Co., Ltd
Product
tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl 452339-71-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1 ton
Release date
2023-11-02
Anhui Yiao New Material Technology Co., Ltd
Product
tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl 452339-71-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1 ton
Release date
2023-11-02

452339-71-8, tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamateRelated Search:

(R)-2-Amino-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)ethanol A-1-(AMINOMETHYL)-4-HYDROXY-1,3-BENZENDIMETHANOL Ethanone, 2-bromo-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)- Ethanol, 2-[(2,6-dichlorophenyl)Methoxy]- Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro 21ξ-morpholino-23,24-dinor-chola-4,20-dien-3-one Androstenone hydrazone 17-Iodoandrosta-5,16-dien-3beta-ol BISNORCHOLENALDEHYDE CarbaMic acid, [(2R)-2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]-, 1,1-diMethylethyl ester 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)- N-(1-Cyclohexen-1-yl)morpholine Vilanterol Impurity 45 Vilanterol Impurity 25 di-(tert-butyl)2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyliMinodicarbonate Vilanterol Impurity 10 Vilanterol Impurity 14 Vilanterol Impurity 11

  • CarbaMic acid, [2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]-, 1,1-diMethylethyl ester
  • tert-Butyl N-(2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl)carbamate
  • tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamate
  • tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl
  • tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate
  • BNKY020-VT02
  • Carbamic acid, [2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]-, 1,1-dimethylethyl ester (9CI)
  • Vilanterol Impurity 37
  • Carbamic acid, N-[2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]-, 1,1-dimethylethyl ester
  • tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoeth...
  • tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamateQ: What is tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamate Q: What is the CAS Number of tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamate
  • Tert - butyl 2-(2,2- dimethyl -4H-1,3- benzodioxin -6- yl )-2- Oxoethylcarb - N -amate
  • Tert-butyl 2- (2,2-dimethyl-4H-1,3-benzodoxin-6-yl) -2-oxoethylcarbamate
  • Vilanterol Impurity 30
  • 452339-71-8
  • Intermediate