ChemicalBook > CAS DataBase List > Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro

Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro

Product Name
Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro
CAS No.
503070-57-3
Chemical Name
Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro
Synonyms
BNKY020-VT06;CAS 503070-57-3;ethoxymethyl]​Bromohexyloxy)​Vilanterol Impurity 28;Vilanterol Impurity 80;Vilanterol intermediate;BROMOHEXYL-OXY- ETHOXYMETHYLCHLOROBENZENE;2-((2-((6-bromohexyl)oxy)methyl)-1,3-dichlorobenzene;2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro
CBNumber
CB62563268
Molecular Formula
C15H21BrCl2O2
Formula Weight
384.14
MOL File
503070-57-3.mol
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Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Property

Boiling point:
420.8±45.0 °C(Predicted)
Density 
1.335±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Oil
color 
Colourless
InChI
InChI=1S/C15H21BrCl2O2/c16-8-3-1-2-4-9-19-10-11-20-12-13-14(17)6-5-7-15(13)18/h5-7H,1-4,8-12H2
InChIKey
AKLUHFHHUBIDQA-UHFFFAOYSA-N
SMILES
C1(Cl)=CC=CC(Cl)=C1COCCOCCCCCCBr
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B683630
Product name
2-[2-(6-Bromohexyloxy)ethoxymethyl]-1,3-dichlorobenzene
Packaging
1g
Price
$55
Updated
2021/12/16
TRC
Product number
B683630
Product name
2-[2-(6-Bromohexyloxy)ethoxymethyl]-1,3-dichlorobenzene
Packaging
5g
Price
$95
Updated
2021/12/16
TRC
Product number
B683630
Product name
2-[2-(6-Bromohexyloxy)ethoxymethyl]-1,3-dichlorobenzene
Packaging
10g
Price
$155
Updated
2021/12/16
TRC
Product number
B683630
Product name
2-[2-(6-Bromohexyloxy)ethoxymethyl]-1,3-dichlorobenzene
Packaging
25g
Price
$370
Updated
2021/12/16
AK Scientific
Product number
1435DT
Product name
2-((2-((6-Bromohexyl)oxy)ethoxy)methyl)-1,3-dichlorobenzene
Packaging
5g
Price
$126
Updated
2021/12/16
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Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Chemical Properties,Usage,Production

Uses

2-[2-(6-Bromohexyloxy)ethoxymethyl]-1,3-dichlorobenzene is an intermediate in the synthesis of Vilanterol Trifenatate-d4 (V260002). Vilanterol Trifenatate (V260000) is a long-acting β2 adrenergic receptor Agonist. It demonstrates prolonged bronchodilation in subjects with asthma and COPD.

Synthesis

100mL single-necked flask, under a nitrogen atmosphere, 2-((2,6-dichlorobenzyl)oxy)ethan-1-ol (3 g, 13.5 mmol) was dissolved in 1,6-dibromo hexane (9.7 g, 40.5 mmol) tetrabutylammonium bromide (432 mg, 1.35mmol) and 50% sodium hydroxide solution (2.5g, 62.1 mmol) was added and reacted at room temperature for 16 hours. Dichloromethane (50 mL), washed successively with water (50 mL) and saturated brine (50 mL), dried over the organic phase, filtered, concentrated and purified on a silica gel column (ethyl acetate/petroleum ether = 1/12) to give a pale yellow oil Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro.

Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Suppliers

China 154 India 5 United States 3 Global 162
Shenzhen HwaGen Pharmaceutical Co.,Ltd
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View Lastest Price from Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro 503070-57-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-30
Anhui Dexinjia Biopharm Co., Ltd
Product
Benzene, 2-[[2-[(6-bromohexyl)oxy]ethoxy]methyl]-1,3-dichloro 503070-57-3
Price
US $1000.00/KG
Min. Order
0.1KG
Purity
98%
Supply Ability
500kg per month
Release date
2020-06-10
Hebei Yanxi Chemical Co., Ltd.
Product
Benzene, 2-[[2-[(6-bromohexyl)oxy]ethoxy]methyl]-1,3-dichloro- 503070-57-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
100tons
Release date
2023-09-15

503070-57-3, Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloroRelated Search:

Cyclopropyl bromide Phosphorus oxybromide OXITROPIUM BROMIDE Ethanone, 2-bromo-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)- Ethanol, 2-[(2,6-dichlorophenyl)Methoxy]- 21ξ-morpholino-23,24-dinor-chola-4,20-dien-3-one Androstenone hydrazone 17-Iodoandrosta-5,16-dien-3beta-ol BISNORCHOLENALDEHYDE tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate CarbaMic acid, [(2R)-2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]-, 1,1-diMethylethyl ester 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)- N-(1-Cyclohexen-1-yl)morpholine Abiraterone

  • Vilanterol Impurity 28
  • Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro
  • 2-[2-(6-BroMohexyloxy)ethoxyMethyl]-1,3-dichlorobenzene
  • Vilanterol intermediate
  • 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro
  • BNKY020-VT06
  • CAS 503070-57-3
  • BROMOHEXYL-OXY- ETHOXYMETHYLCHLOROBENZENE
  • 2- [2- (6-bromohexaoxy) ethoxymethyl] -1,3-dichlorobenzene
  • 2-((2-((6-bromohexyl)oxy)methyl)-1,3-dichlorobenzene
  • Bromohexyloxy)&#8203
  • ethoxymethyl]&#8203
  • Vilanterol Impurity 80
  • 503070-57-3
  • 503070-53-0
  • C15H21BrCl2O2
  • Intermediate
  • 503070-57-3