Chemical properties Toxicity Application Preparation Category Flammability and Hazardous characteristics Storage characteristics warehouse Fire extinguishing agent
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Phosphorus oxybromide

Chemical properties Toxicity Application Preparation Category Flammability and Hazardous characteristics Storage characteristics warehouse Fire extinguishing agent
Product Name
Phosphorus oxybromide
CAS No.
7789-59-5
Chemical Name
Phosphorus oxybromide
Synonyms
POBr3;phosphorus(v) oxybromide;Phosphoryl tribromide;PHOSPHOROUS OXYBROMIDE;PHOSPHORYL BROMIDE;phosphoryltribromide;AURORA KA-1088;Formylmelphalan;Phosphorictribromide;Phosphorus(V) oxybro
CBNumber
CB5377198
Molecular Formula
Br3OP
Formula Weight
286.69
MOL File
7789-59-5.mol
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Phosphorus oxybromide Property

Melting point:
56 °C(lit.)
Boiling point:
192 °C(lit.)
Density 
2.82 g/mL at 25 °C(lit.)
Flash point:
189°C
storage temp. 
Store below +30°C.
solubility 
reacts with H2O; soluble in benzene, ethyl ether,chloroform
form 
Lump
Specific Gravity
2.822
color 
White to yellow
Water Solubility 
decomposes
Sensitive 
Moisture Sensitive
Merck 
14,7348
InChIKey
UXCDUFKZSUBXGM-UHFFFAOYSA-N
CAS DataBase Reference
7789-59-5(CAS DataBase Reference)
NIST Chemistry Reference
Phosphorus tribromide oxide(7789-59-5)
EPA Substance Registry System
Phosphoric tribromide (7789-59-5)
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Safety

Hazard Codes 
C
Risk Statements 
14-34-37
Safety Statements 
26-36/37/39-43-45-7/8-Neverusewater.
RIDADR 
UN 1939 8/PG 2
WGK Germany 
3
10-21
Hazard Note 
Corrosive
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
28129090
Hazardous Substances Data
7789-59-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.21026
Product name
Phosphoryl bromide
Purity
for synthesis
Packaging
25g
Price
$237
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21026
Product name
Phosphoryl bromide
Purity
for synthesis
Packaging
100g
Price
$378
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21026
Product name
Phosphoryl bromide
Purity
for synthesis
Packaging
1kg
Price
$1160
Updated
2024/03/01
Sigma-Aldrich
Product number
376949
Product name
Phosphorus(V) oxybromide
Purity
>95%
Packaging
25g
Price
$228
Updated
2024/03/01
Alfa Aesar
Product number
056135
Product name
Phosphorus(V) oxybromide, 98% min
Packaging
5g
Price
$45.9
Updated
2024/03/01
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Phosphorus oxybromide Chemical Properties,Usage,Production

Chemical properties

It appears as colorless or pale orange crystal with irritating odor. It has a relative density of 2.822, melting temperature of 56 °C, the boiling point of 191.7 ℃ and the evaporation heat of 38 Kj/mol. It is soluble in ether, benzene, chloroform, carbon disulfide, concentrated sulfuric acid. It can be slowly hydrolyzed to phosphoric acid and HBr in water.

Toxicity

It has similar toxicity to the phosphorus oxychloride. It can react with water, emitting a white smoke-like, irritant and corrosive hydrogen bromide gas which has strong irritation to the eyes, mucous membranes and skin. The patients having inhaled of the vapor or smoke should be sent away from the contaminated area for rest and keeping warm. If eyes are irritated, rinse with water. Upon severe cases, send for medical treatment. Upon skin contact, first rinse with water, and then thoroughly wash with soap. If burned, go for medical treatment. Upon mistakenly administration, immediately gargle and immediately go to the hospital for treatment.

Application

During the chemical process, it can be used as an intermediate and used as the raw materials for manufacturing the bromine flame retardant.

Preparation

Phosphorus oxychloride method: take phosphorus oxychloride as raw material and aluminum trichloride as the catalyst, upon heating at about 80 ℃, introduce hydrogen bromide gas for reaction, generating tribromo phosphorus. The reaction is:
POC13 + 3HBr → POBr3 + 3HCl ↑
The produced hydrogen chloride gas during the reaction, after being absorbed by water, can produce dilute hydrochloric acid.
Phosphorus tribromide method: to a round bottom flask equipped with a reflow condenser, add the mixture of phosphorus pentabromide and phosphorus pentoxide (250 g of PBr5/about 30 g of P2O5) and heat slowly to 150 ° C. Phosphorus pentoxide is a bit more than the phosphorus pentabromide in stoichiometry. At this time, one the one hand, pay attention to expel the bromine out; on the other hand, make sure that the reaction is completed within 5h.
Then, 10 g of bromine and equivalent amount of phosphorus pentoxide were added to the melt and refluxed at 150 ° C for several hours. This is because it takes time for the intermediate product, phosphorus tribromide, to be oxidized to phosphorus pentabromide and transited to tribromonic phosphorus. The resultant was subjected to vacuum distillation under reduced pressure. After removing the initial distillate and the phosphorus tribromide contained therein, the trapping was carried out. The receiver is cooled with ice brine to generate tribromo phosphorus. Its reaction is:
3PBr5 + P2O5 → 5POBr3

Category

corrosive items

Flammability and Hazardous characteristics

It is subject to decomposition upon coming across water, generating toxic hydrogen bromide gas.

Storage characteristics warehouse

ventilated, low temperature and dry; it should be stored separately from combustible product.

Fire extinguishing agent

Dry powder

Chemical Properties

colorless to grey-brown crystals or fused mass

Uses

Phosphorus(V) Oxybromide is a reagent used in the preparation of phosphoryl halide for N-protection of amino acids using group assisted purification (GAP). Phosphorus(V) Oxybromide is a brominating agent.

Uses

Phosphorus(V) oxybromide may be used as brominating reagent in the synthesis of 2,4,6-tribromopyrimidine. It may be used in the preparation of bromoheterocyclic compounds.

General Description

A colorless crystalline solid or liquid if heated above 133° F with a pungent odor. Phosphorus oxybromide is commonly heated and shipped in a molten state. Soluble in water, but, decomposed by water to hydrobromic and phosphoric acid with evolution of heat. Reacts with organic materials to cause fire. Evolves highly toxic and corrosive gases when exposed to fire. Corrosive to metals and tissue. Used to make other chemicals.

Reactivity Profile

Phosphorus oxybromide is incompatible with water, strong oxidizing agents, alcohols, bases, including amines. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Health Hazard

CORROSIVE and/or TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Fire will produce irritating, corrosive and/or toxic gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

EXCEPT FOR ACETIC ANHYDRIDE (UN1715), THAT IS FLAMMABLE, some of these materials may burn, but none ignite readily. May ignite combustibles (wood, paper, oil, clothing, etc.). Substance will react with water (some violently), releasing corrosive and/or toxic gases and runoff. Flammable/toxic gases may accumulate in confined areas (basement, tanks, hopper/tank cars, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water. Substance may be transported in a molten form.

Safety Profile

Poison by ingestion, inhalation, and shin contact. A corrosive irritant to skin, eyes, and mucous membranes. A corrosive material. Reacts with steam, water to produce much heat with toxic fumes. When heated to decomposition it emits very toxic fumes of Brand POx. See also BROMIDES.

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Phosphorus oxybromide Suppliers

Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Nanjing Xiezun Chemical Co., Ltd.
Tel
025-85629050 13912997845
Fax
025-85620080
Email
179109486@qq.com
Country
China
ProdList
25
Advantage
60
Shaanxi Dideu Medichem Co. Ltd
Tel
029-81024372 15029046529
Fax
029-88380327
Email
1027@dideu.com
Country
China
ProdList
10009
Advantage
58
shanghaidelaikekejiyouxiangongsi
Tel
17351445187
Email
3528434302@qq.com
Country
China
ProdList
282
Advantage
58
Jinan Junhe Pharmaceutical Co., Ltd
Tel
13475558980
Email
644535754@qq.com
Country
China
ProdList
299
Advantage
58
Shandong YingLang Chemical Co.,Ltd
Tel
188-88295188 15265310975
Fax
+86-531-88999750
Email
chen@chemwww.com
Country
China
ProdList
4635
Advantage
58
zibofeifanhuagong
Tel
0533-18678146875 18678146875
Email
ziwenrong@163.com
Country
China
ProdList
10
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from Phosphorus oxybromide manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Phosphorus oxybromide 7789-59-5
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50ton
Release date
2020-05-20
Career Henan Chemical Co
Product
Phosphorus oxybromide 7789-59-5
Price
US $1.00/KG
Min. Order
1G
Purity
99%
Supply Ability
100kg
Release date
2018-08-12

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