Description References
ChemicalBook > CAS DataBase List > Pyridazine, 3-bromo- (9CI)

Pyridazine, 3-bromo- (9CI)

Description References
Product Name
Pyridazine, 3-bromo- (9CI)
CAS No.
88491-61-6
Chemical Name
Pyridazine, 3-bromo- (9CI)
Synonyms
3-bromopyridazine;3-bromo- (9CI);Pyridazine, 3-broMo-;3-Bromopyridazine ,97%;Pyridazine, 3-bromo- (9CI);3-broMopyridazine hydrobroMide;Pyridazine, 3-bromo- (9CI) ISO 9001:2015 REACH
CBNumber
CB11044310
Molecular Formula
C4H3BrN2
Formula Weight
158.98
MOL File
88491-61-6.mol
More
Less

Pyridazine, 3-bromo- (9CI) Property

Melting point:
73-74 °C
Boiling point:
270.0±13.0 °C(Predicted)
Density 
1.726±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
form 
solid
pka
0.99±0.10(Predicted)
color 
Yellow to reddish brown
CAS DataBase Reference
88491-61-6
More
Less

Safety

HS Code 
2933998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B695863
Product name
3-Bromopyridazine
Packaging
100mg
Price
$45
Updated
2021/12/16
ChemScene
Product number
CS-W004020
Product name
3-Bromopyridazine
Purity
99.83%
Packaging
1g
Price
$55
Updated
2021/12/16
Oakwood
Product number
078228
Product name
3-Bromopyridazine
Packaging
250mg
Price
$26
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB72022
Product name
3-Bromopyridazine
Packaging
250mg
Price
$65
Updated
2021/12/16
Oakwood
Product number
078228
Product name
3-Bromopyridazine
Packaging
1g
Price
$76
Updated
2021/12/16
More
Less

Pyridazine, 3-bromo- (9CI) Chemical Properties,Usage,Production

Description

3-Bromopyridine can undergo lithiation with LDA at low temperatures in the 4-position: Heterocycles, involved in formation of the Grignard by Mg exchange with i-PrMgCl and in transmetallation of the lithiated derivative with zinc chloride followed by treatment with an electrophile as a route to 4-substituted 3-bromopyridines1-4. 3-Bromopyridine is also used as an intermediate in the synthesis of Active Pharmaceutical Ingredients especially Abiraterone acetate (an antiandrogen medication which is used in the treatment of prostate cancer) and Zimelidine (selective serotonin reuptake inhibitor (SSRI) antidepressants)5.

References

  1. Jennifer A. Love Dr.; John P. Morgan.;Tina M. Trnka.;Robert H. Grubbs Prof. A Practical and Highly Active Ruthenium-Based Catalyst that Effects the Cross Metathesis of Acrylonitrile. Angewandte Chemie International Edition. 2002, 41 (21), 4035-4037.
  2. Wenjie Li.; Dorian P. Nelson.; Mark S. Jensen.; R. Scott Hoerrner.; Dongwei Cai.; Robert D. Larsen.; Paul J. Reider. An Improved Protocol for the Preparation of 3-Pyridyland Some Arylboronic Acids. J. Org. Chem. 2002, 57 (16), 5394-5397.
  3. https://www.alfa.com/en/catalog/A12894/
  4. Cai, Dongwei, R. D. Larsen, and P. J. Reider. "Effective lithiation of 3-bromopyridine: synthesis of 3-pyridine boronic acid and variously 3-substituted pyridines." Cheminform 33.38(2002):4285-4287.
  5. www.jubl.com/uploads/files/48msds_msds-3-bromopyridine.pdf

Pyridazine, 3-bromo- (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Pyridazine, 3-bromo- (9CI) Suppliers

SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
668
Advantage
55
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17939
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Jinan Trio PharmaTech Co., Ltd.
Tel
+86 (531) 88811783
Fax
+86 (531) 55696010 QQ 1762738062
Email
sales@trio-pharmatech.com (International market)
Country
China
ProdList
1856
Advantage
62
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
More
Less

View Lastest Price from Pyridazine, 3-bromo- (9CI) manufacturers

Henan Fengda Chemical Co., Ltd
Product
3-Bromopyridazine 88491-61-6
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-02
Shaanxi Dideu Medichem Co. Ltd
Product
Pyridazine, 3-bromo- (9CI) 88491-61-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-04-29
Shanghai Rlavie Technology Co ltd
Product
3-bromopyridazine 88491-61-6
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
100kgs/month
Release date
2021-11-27